Dr. Gauthier is Assistant Professor of Palliative Care in the Department of Family Medicine and Emergency Medicine of the Faculty of Medicine at Laval University. She is also a regular researcher in the oncology axis of the CHU of Quebec-Laval University Research Centre, as well as in the Michel-Sarrazin Research Team in Psychosocial Oncology and Palliative Care (ERMOS). She is also co-director of the Axis 1 of the Quebec Research Network in Palliative and End-of-Life Care (RQSPAL) and a regular member of the Quebec Pain Research Network. She completed her PhD at the School of Kinesiology and Health Sciences at York University in Toronto in 2013 and her postdoctoral at the Princess Margaret Cancer Center in 2016. Her research goals are at the intersection of pain and aging. Her main objective is to improve the assessment and management of pain during adulthood, particularly in the elderly population. Dr. Gauthier aims to deepen our understanding of pain, its management, as well as to identify ways to improve it in order to reduce patients’ suffering.

The overall impact of chemotherapy-induced peripheral neuropathies

Women using taxane-based chemotherapy to treat breast cancer may experience persistent side effects from these treatments, such as chemically-induced peripheral neuropathy (CIPN). These symptoms include weakness, pain, numbness, altered sensitivity, tingling, or burning sensations in the hands and feet. These symptoms can cause temperature-related injuries, balance problems, falls, and a deterioration in the quality of life. Unfortunately, our knowledge of CIPN and the best way to measure it are limited. As part of her research projects, Dr. Gauthier is interested in examining the psychometric properties of measures used to evaluate chemically-induced peripheral neuropathy, in order to improve our understanding of the development, trajectory, biopsychosocial risk factors, and impacts of CIPN by age. Additionally, by comparing the validity of existing measures used in evaluating acute and chronic CIPNs, it will be possible to better determine which of the measures has the best validity and should serve as basis for the development of a new measure, if necessary.

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Gagliese L, Gauthier LR, Narain N, Freedman T

Pain, aging and dementia: Towards a biopsychosocial model.

Journal Article

Prog Neuropsychopharmacol Biol Psychiatry, 87 (Pt B), pp. 207-215, 2018, ISSN: 0278-5846.

Abstract | Links:

Gewandter JS, Brell J, Cavaletti G, Dougherty PM, Evans S, Howie L, McDermott MP, O'Mara A, Smith AG, Dastros-Pitei D, Gauthier LR, Haroutounian S, Jarpe M, Katz NP, Loprinzi C, Richardson P, Lavoie-Smith EM, Wen PY, Turk DC, Dworkin RH, Freeman R

Trial designs for chemotherapy-induced peripheral neuropathy prevention: ACTTION recommendations.

Journal Article

Neurology, 91 (9), pp. 403-413, 2018, ISSN: 0028-3878.

Abstract | Links:

Gauthier LR, Dworkin RH, Warr D, Pillai Riddell R, Macpherson AK, Rodin G, Zimmermann C, Lawrence Librach S, Moore M, Shepherd FA, Gagliese L

Age-Related Patterns in Cancer Pain and Its Psychosocial Impact: Investigating the Role of Variability in Physical and Mental Health Quality of Life.

Journal Article

Pain Med, 19 (4), pp. 658-676, 2018, ISSN: 1526-2375.

Abstract | Links:

Mah K, Tran KT, Gauthier LR, Rodin G, Zimmermann C, Warr D, Librach SL, Moore M, Shepherd FA, Gagliese L

Do Correlates of Pain-Related Stoicism and Cautiousness Differ in Younger and Older People With Advanced Cancer?

Journal Article

J Pain, 19 (3), pp. 301-316, 2018, ISSN: 1526-5900.

Abstract | Links:

St-Pierre D, Bouchard K, Gauthier L, Chiquette J, Dorval M, Centre ROSE

Perspectives of Women Considering Bilateral Prophylactic Mastectomy and their Peers towards a Telephone-Based Peer Support Intervention.

Journal Article

J Genet Couns, 27 (1), pp. 274-288, 2018, ISSN: 1059-7700.

Abstract | Links:

Gewandter JS, Freeman R, Kitt RA, Cavaletti G, Gauthier LR, McDermott MP, Mohile NA, Mohlie SG, Smith AG, Tejani MA, Turk DC, Dworkin RH

Chemotherapy-induced peripheral neuropathy clinical trials: Review and recommendations.

Journal Article

Neurology, 89 (8), pp. 859-869, 2017, ISSN: 0028-3878.

Abstract | Links:

Mah K, Tran KT, Gauthier LR, Rodin G, Zimmermann C, Warr D, Librach SL, Moore M, Shepherd FA, Gagliese L

Psychometric Evaluation of the Pain Attitudes Questionnaire-Revised for People With Advanced Cancer.

Journal Article

J Pain, 18 (7), pp. 811-824, 2017, ISSN: 1526-5900.

Abstract | Links:

Gauthier LR, Young A, Dworkin RH, Rodin G, Zimmermann C, Warr D, Librach SL, Moore M, Shepherd FA, Pillai Riddell R, Macpherson A, Melzack R, Gagliese L

Validation of the short-form McGill pain questionnaire-2 in younger and older people with cancer pain.

Journal Article

J Pain, 15 (7), pp. 756-70, 2014, ISSN: 1526-5900.

Abstract | Links:

Gauthier LR, Rodin G, Zimmermann C, Warr D, Librach SL, Moore M, Shepherd FA, Gagliese L

The communal coping model and cancer pain: the roles of catastrophizing and attachment style.

Journal Article

J Pain, 13 (12), pp. 1258-68, 2012, ISSN: 1526-5900.

Abstract | Links:

Gauthier LR, Gagliese L

Bereavement Interventions, End-of-Life Cancer Care, and Spousal Well-Being: A Systematic Review

Journal Article

Clin Psychol (New York), 19 , pp. 72-92, 2012, ISSN: 0969-5893.

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Active projects

  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Centre de recherche sur les soins et les services de première ligne de l'Université Laval (CERSSPL-UL), Subvention, CIUSSS - CN - Centre de recherche sur les soins et les services de première ligne de l'ULaval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre hospitalier universitaire de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • La neuropathie périphérique chimio-induite chez les femmes de différents âges recevant une chimiothérapie à base de taxane pour un cancer du sein, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2018-07-01 to 2022-06-30
  • PainQuILT: A patient-centred e-health solution to empower older adults and improve pain assessment and management, Subvention, Instituts de recherche en santé du Canada, Programme de subvention Catalyseur, from 2017-09-01 to 2019-08-31
  • Programme de soutien aux nouveaux chercheurs, Subvention, Université Laval - démarrage nouveau chercheur, Soutien facultaire aux jeunes chercheurs de la Faculté de médecine, from 2018-07-01 to 2020-06-30
  • Subvention d’établissement de jeune chercheur - Lynn Gauthier, Subvention, Fonds de recherche du Québec - Santé, Établissement de jeunes chercheurs - Juniors 1, from 2018-07-01 to 2022-06-30

Recently finished projects

  • (FRSQ 73914) Soutien de votre projet de recherche sur le cancer du sein, Subvention, Fondation du CHU de Québec, from 2016-05-26 to 2017-05-25
  • (FRSQ 73930) Soutien du projet de recherche en oncologie (Chemotherapy-induced peripheral neuropath: development of a research program to evaluate its measurement, development, chronicity, risk factors, and impact across the adult lifespan), Subvention, Fondation du CHU de Québec, from 2016-07-01 to 2017-06-30
  • (FRSQ 77470) «PainQuILT: Preliminary evaluation of a digital pain assessment and tracking tool in English- and French-speaking older adults with pain», Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2017-01-19 to 2018-03-31
  • (FRSQ 82601)Projet de plateforme de ressources communes minimal dataset, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-05-01 to 2019-03-31
  • Cancer pain in Canada: Mapping the availability of pain management services and charting gaps and disparities in access to care, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-04-01 to 2019-03-31
  • Fonds de démarrage (Chaire en soins palliatifs), Subvention, Fondation de l'Université Laval, from 2016-04-01 to 2019-04-30
  • Measurement of chemotherapy - induced peripheral neuropathy across the adult lifespan, Subvention, Société canadienne pour le traitement de la douleur, 2016 Early Career Investigator Pain Research Grant, from 2016-04-01 to 2017-09-15
Data provided by the Université Laval research projects registery