Dr. Louise Provencher is a surgeon-oncologist at the CHU de Québec-Laval University. She is also a clinical researcher at the Research Center of the CHU de Québec-Laval University, and clinical professor at the Laval University School of Medicine. Dr. Provencher is part of the research group of the Centre des Maladies du Sein of CHU de Québec-Laval University.
Dr. Provencher is a scientific committee member at the McPeak-Sirois research group and the CHU de Quebec leader for the National Surgical Adjuvant Breast and Bowel Project.
Using structured breast cancer data
The Centre des Maladies du Sein research team has a comprehensive database of all cancers diagnosed since 1974; more than 12,000 patients are listed. A database of biopsy data from 1999 is also available; data on more than 34,000 biopsies are listed. These databases allow quality publications that modify the management and follow-up of cancers and benign breast diseases.
Offer innovative treatments
The Centre des Maladies du Sein of CHU de Québec-Laval University research group is one of the largest in Canada offering innovative treatments for breast cancer. More than 50 clinical trials are active at all times and are offered to patients who consult at the clinic or are referred by clinics/hospitals in the area. These clinical trials provide access to innovative experimental medications and develop the expertise of our world-renowned oncologists.
Supporting quality of life
The Centre des Maladies du Sein of CHU de Québec-University research group is a pioneer in quality of life studies in breast cancer, from total mastectomy to partial mastectomy, to the use of the cooling cap to counteract hair loss, promoting physical activity to improve survivorship, including optimal preservation of the axillary lymph nodes. The research group is at the forefront of studies promoting quality of life despite the adverse effects of the disease on an individual’s life.
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Centre des maladies du sein Deschênes-Fabia
Québec, Québec
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The efficacy and safety of enzalutamide with trastuzumab in patients with HER2+ and androgen receptor-positive metastatic or locally advanced breast cancer.
Journal ArticleBreast Cancer Res Treat, 2021, ISSN: 0167-6806.
DNA Methylation and Breast Cancer Risk: An Epigenome-Wide Study of Normal Breast Tissue and Blood.
Journal ArticleCancers (Basel), 12 (11), 2020, ISSN: 2072-6694.
Insomnia, immunity, and infections in cancer patients: Results from a longitudinal study.
Journal ArticleHealth Psychol, 39 (5), pp. 358-369, 2020, ISSN: 0278-6133.
Wage losses among spouses of women with nonmetastatic breast cancer.
Journal ArticleCancer, 126 (5), pp. 1124-1134, 2020, ISSN: 0008-543X.
NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1+ or 2.
Journal ArticleJ Clin Oncol, 38 (5), pp. 444-453, 2020, ISSN: 0732-183X.
Development of a community pharmacy-based intervention to enhance adherence to adjuvant endocrine therapy among breast cancer survivors guided by the Intervention Mapping approach.
Journal ArticleRes Social Adm Pharm, 16 (12), pp. 1724-1736, 2020, ISSN: 1551-7411.
Is contralateral breast ultrasound worthwhile in preoperative staging of breast cancer?
Journal ArticleJ Clin Ultrasound, 47 (4), pp. 195-200, 2019, ISSN: 0091-2751.
Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer.
Journal ArticleN Engl J Med, 380 (7), pp. 617-628, 2019, ISSN: 0028-4793.
Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial.
Journal ArticleJ Clin Oncol, 37 (3), pp. 178-189, 2019, ISSN: 0732-183X.
Evaluating A Multidisciplinary Cancer Conference Checklist: Practice Versus Perceptions.
Journal ArticleJ Multidiscip Healthc, 12 , pp. 883-891, 2019, ISSN: 1178-2390.
Active projects
- Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
- Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
- Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2024-09-30
- Omega-3 fatty acids in the prevention of breast cancer: role of obesity-related markers in breast tissues, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2018-10-01 to 2026-09-30
- Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-10-01 to 2022-02-28
Recently finished projects
- Excellence in advanced cancer clinical trials initiative (the ExACCT Initiavive) , Subvention, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC), Réseau de centres d'excellence (RCE), from 2017-01-18 to 2020-03-31
- MA-12: Étude randomisée à double insu visant à comparer le tamoxifène avec un placebo chez les patientes atteintes d'un cancer du sein étendu aux ganglions lymphatiques et qui ont complété une chimiothérapie adjuvante ..., Subvention, L'Institut de recherche de la Société canadienne du cancer, Subvention de recherche, from 1997-04-01 to 2020-03-31
- Mise à jour des connaissances en cancer du sein, Subvention, Pfizer Canada Inc., from 2018-01-24 to 2020-03-31
- NSABP Breast Cancer Treatment Protocols, Subvention, National Institute of Health (USA), Subvention de recherche, from 1997-02-01 to 2020-01-31
- Towards better outcomes for young women with breast cancer : A pan-canadian collaborative - Reducing the bUrden of Breast cancer in Young women (RUBY), Subvention, Women's College Hospital, from 2016-03-10 to 2020-03-31
- Utilisation de l'intelligence artificielle afin de maintenir automatiquement le registre national de suivi en cancer du sein et du projet de recherche en cancer du sein associé, Subvention, Fondation du cancer du sein du Québec, from 2019-01-01 to 2020-12-31