Dr. Louise Provencher is a surgeon-oncologist at the CHU de Québec-Laval University. She is also a clinical researcher at the Research Center of the CHU de Québec-Laval University, and clinical professor at the Laval University School of Medicine. Dr. Provencher is part of the research group of the Centre des Maladies du Sein of CHU de Québec-Laval University.

Dr. Provencher is a scientific committee member at the McPeak-Sirois research group and the CHU de Quebec leader for the National Surgical Adjuvant Breast and Bowel Project.

Using structured breast cancer data

The Centre des Maladies du Sein research team has a comprehensive database of all cancers diagnosed since 1974; more than 12,000 patients are listed. A database of biopsy data from 1999 is also available; data on more than 34,000 biopsies are listed. These databases allow quality publications that modify the management and follow-up of cancers and benign breast diseases.

Offer innovative treatments

The Centre des Maladies du Sein of CHU de Québec-Laval University research group is one of the largest in Canada offering innovative treatments for breast cancer. More than 50 clinical trials are active at all times and are offered to patients who consult at the clinic or are referred by clinics/hospitals in the area. These clinical trials provide access to innovative experimental medications and develop the expertise of our world-renowned oncologists.

Supporting quality of life

The Centre des Maladies du Sein of CHU de Québec-University research group is a pioneer in quality of life studies in breast cancer, from total mastectomy to partial mastectomy, to the use of the cooling cap to counteract hair loss, promoting physical activity to improve survivorship, including optimal preservation of the axillary lymph nodes. The research group is at the forefront of studies promoting quality of life despite the adverse effects of the disease on an individual’s life.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
Centre des maladies du sein Deschênes-Fabia
Québec, Québec
Canada G1S 4L8
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Nabi H, Provencher L, Diorio C

RE: Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424).

Journal Article

J Natl Cancer Inst, 2018, ISSN: 0027-8874.

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Poirier E, Desbiens C, Poirier B, Boudreau D, Jacob S, Lemieux J, Doyle C, Diorio C, Hogue JC, Provencher L

In response to: Long-term overall survival of patients diagnosed with pure tubular carcinoma of the breast might be affected by increased co-morbidities.

Journal Article

J Surg Oncol, 2018, ISSN: 0022-4790.

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Poirier E, Desbiens C, Poirier B, Boudreau D, Jacob S, Lemieux J, Doyle C, Diorio C, Hogue JC, Provencher L

Characteristics and long-term survival of patients diagnosed with pure tubular carcinoma of the breast.

Journal Article

J Surg Oncol, 2017, ISSN: 0022-4790.

Abstract | Links:

Furrer D, Jacob S, Michaud A, Provencher L, Lemieux J, Diorio C

Association of Tobacco Use, Alcohol Consumption and HER2 Polymorphisms With Response to Trastuzumab in HER2-Positive Breast Cancer Patients.

Journal Article

Clin Breast Cancer, 2017, ISSN: 1526-8209.

Abstract | Links:

Tremblay-LeMay R, Hogue JC, Provencher L, Poirier B, Poirier E, Laberge S, Diorio C, Desbiens C

How Wide Should Margins Be for Phyllodes Tumors of the Breast?

Journal Article

Breast J, 23 (3), pp. 315-322, 2017, ISSN: 1075-122X.

Abstract | Links:

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Active projects

  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Centre hospitalier universitaire de Québec - CHU de Québec-Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2020-06-30
  • Soutien aux femmes nouvellement métastatiques d'un cancer du sein, Subvention, Fondation du cancer du sein du Québec, from 2015-06-01 to 2018-05-31

Recently finished projects

  • A phase II randomized study evaluating the biological and clinical effects of the combination of palbociclib with letrozole as neoadjuvant therapy in women with estrogen receptor-positive primary breast cancer, Subvention, National Surgical Adjuvant Breast and Bowel Projects, from 2016-03-30 to 2017-03-31
  • A rando, placebo-contr, dble-blind ph. 3 study eval. safety and efficacy of the addition of velaparib + carboplatin vs the addition of carboplatin to standard neoadjuvant chemotherapy in subjects with early stage triple neg. breast cancer, Subvention, National Surgical Adjuvant Breast and Bowel Projects, from 2015-09-17 to 2017-03-31
  • Creating meaning following advanced cancer : A cognitive - existential telephone intervention to improve existential and global quality of life, Subvention, L'Institut de recherche de la Société canadienne du cancer, Subventions de recherche sur l’amélioration de la qualité de vie, from 2014-02-01 to 2017-01-31
  • Développement d'une base de données sur les biopsies pour l'évaluation des cancers du sein., Subvention, Fondation du CHU de Québec, from 2017-04-03 to 2018-03-31
  • Développement d'une intervention offerte en pharmacie communautaire visant à favoriser l'adhésion à l'hormonothérapie adjuvante chez les femmes ayant eu un cancer du sein, Subvention, Fondation de l'Université Laval, from 2017-02-01 to 2018-03-31
  • DNA methylation in normal breast tissue associated to risk of second contralateral breast cancer., Subvention, L'Institut de recherche de la Société canadienne du cancer, Subventions pour l'innovation, from 2014-02-01 to 2018-01-30
  • Enhancing adherence to adjuvant endocrine therapy among breast cancer survivors: Pilot study of the S.O.I.E. program, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-04-01 to 2018-04-30
  • MA-12: Étude randomisée à double insu visant à comparer le tamoxifène avec un placebo chez les patientes atteintes d'un cancer du sein étendu aux ganglions lymphatiques et qui ont complété une chimiothérapie adjuvante ..., Subvention, L'Institut de recherche de la Société canadienne du cancer, Subvention de recherche, from 1997-04-01 to 2017-03-31
  • Mise à jour de la base de données des biopsies percutanées du sein., Subvention, Fondation du CHU de Québec, from 2016-05-02 to 2017-03-31
  • NSABP Breast Cancer Treatment Protocols, Subvention, National Institute of Health (USA), Subvention de recherche, from 1997-02-01 to 2017-01-31
  • Phase III study evaluating palbociclib (PD-0332991) a cyclin-dependent kinase(CDK) 4/6 inhibitor in patients with hormone-receptor-positive, HER2- normal primary breast cancer with high relapse risk after neoadjuvant chemotherapy (PENELOPE), Subvention, National Surgical Adjuvant Breast and Bowel Projects, from 2015-04-29 to 2017-03-31
  • Soutien de projets de recherche sur les maladies du sein., Subvention, Fondation du CHU de Québec, from 2015-09-23 to 2016-09-22
  • Support aux essais cliniques en cancer du sein., Subvention, Fondation du CHU de Québec, from 2017-04-03 to 2018-03-31
  • Towards better outcomes for young women with breast cancer : A pan-canadian collaborative - Reducing the bUrden of Breast cancer in Young women (RUBY), Subvention, Women's College Hospital, from 2016-03-10 to 2017-03-31
Data provided by the Université Laval research projects registery