Dr. Line Guénette is a researcher within the Population Health and Health Best Practices Axis of the CHU of Quebec-Laval University Research Centre, as well as an Associate Professor in the Faculty of Pharmacy at Laval University. She is also a clinical pharmacist within the CIUSSS de la Capitale-Nationale. Her research program aims to identify and better understand the issues of drug use, particularly in people with diabetes and the elderly. She is also working to find efficient ways to optimize the use of medicines and to transform professional practices.

She is the recipient of a clinical investigator-junior 1 fellowship from the Fonds de la recherche Québec-Santé (FRQ-S) and of the FRQ-S/Société québécoise d’hypertension artérielle (SQHA) Jacques-de-Champlain Scholarship.

Towards a better understanding of the problems of drug use

Although there are now several effective and well-tolerated drugs to control several chronic diseases and reduce associated complications, problems of poor control are still too common. One of the most important barriers to optimal treatment of chronic diseases is the non-optimal use of drugs by patients and health professionals. The first step to optimize the use of medicines is to better understand the determinants of misuse. Dr. Guénette and her team are achieving this by using large databases of administrative data or surveys of patients and health professionals.

Optimizing the use of medicines

According to recent literature reviews, studies that evaluate the effectiveness of interventions to optimize drug use often have important methodological shortcomings. Moreover, very few of them describe in detail the applied interventions, the targeted determinants and the design of the interventions. It is therefore essential to improve research on the best ways to intervene and on the interventions most likely to be implemented in the Quebec context. It is also crucial to work towards reducing inappropriate practices and implementing new knowledge and activities with proven benefits. To achieve this, Dr. Guénette works closely with clinicians and decision-makers in clinical settings. A project to implement and evaluate the impact of pharmacists’ new activities under Bill 41 is currently underway.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
J1-08
Québec, Québec
Canada G1S 4L8
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Guenette L, Chagnon A, Turcotte V

User experience with the Ask Your Pharmacist teleconsultation platform.

Journal Article

Can Pharm J (Ott), 154 (3), 2021.

Abstract | Links:

Garland CT, Guenette L, Kroger E, Carmichael PH, Rouleau R, Sirois C

A New Care Model Reduces Polypharmacy and Potentially Inappropriate Medications in Long-Term Care.

Journal Article

J Am Med Dir Assoc, 22 (1), 2021.

Abstract | Links:

Fenelon-Dimanche R, Guenette L, Trudel-Bourgault F, Yousif A, Lalonde G, Beauchesne MF, Collin J, Blais L

Development of an electronic tool (e-AdPharm) to address unmet needs and barriers of community pharmacists to provide medication adherence support to patients.

Journal Article

Res Social Adm Pharm, 17 (3), 2021.

Abstract | Links:

Lacasse A, Gagnon V, Nguena Nguefack HL, Gosselin M, Page MG, Blais L, Guenette L

Chronic pain patients' willingness to share personal identifiers on the web for the linkage of medico-administrative claims and patient-reported data: The chronic pain treatment cohort.

Journal Article

Pharmacoepidemiol Drug Saf, 30 (8), 2021.

Abstract | Links:

Lunghi C, Zongo A, Tardif I, Demers E, Guenette L, Diendéré JDR

Depression but not non-persistence to antidiabetic drugs is associated with mortality in type 2 diabetes: A nested case-control study.

Journal Article

Diabetes Res Clin Pract, 171 , 2021.

Abstract | Links:

Poirier C, Martel MO, Bérubé M, Boulanger A, Gélinas C, Guénette L, Lacasse A, Lussier D, Tousignant-Laflamme Y, Pagé MG

French-Canadian translation of a self-report questionnaire to monitor opioid therapy for chronic pain: The Opioid Compliance Checklist (OCC-FC).

Journal Article

Can J Pain, 4 (1), 2020.

Abstract | Links:

Leclerc J, Blais C, Rochette L, Hamel D, Guenette L, Beaudoin C, Poirier P

Public Health Outcomes May Differ After Switching from Brand-Name to Generic Angiotensin II Receptor Blockers.

Journal Article

Drugs R D, 20 (2), 2020.

Abstract | Links:

Samir Abdin M, Grenier-Gosselin L, Guenette L

Impact of pharmacists' interventions on the pharmacotherapy of patients with complex needs monitored in multidisciplinary primary care teams.

Journal Article

Int J Pharm Pract, 28 (1), 2020.

Abstract | Links:

Fenelon-Dimanche R, Guenette L, Yousif A, Lalonde G, Beauchesne MF, Collin J, Blais L

Monitoring and managing medication adherence in community pharmacies in Quebec, Canada.

Journal Article

Can Pharm J (Ott), 153 (2), 2020.

Abstract | Links:

Hudon C, Chouinard MC, Aubrey-Bassler K, Muhajarine N, Burge F, Bush PL, Danish A, Ramsden VR, Legare F, Guenette L, Morin P, Lambert M, Fick F, Cleary O, Sabourin V, Warren M, Pluye P

Case Management in Primary Care for Frequent Users of Health Care Services: A Realist Synthesis.

Journal Article

Ann Fam Med, 18 (3), 2020.

Abstract | Links:

64 entries « 1 of 7 »
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Active projects

  • Adhésion aux recommandations nutritionnelles et à la pharmacothérapie dans le traitement du diabète de type 2 : les deux font la paire ?, from 2021-07-08 to 2022-03-31
  • Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: implementation and realist evaluations, from 2018-01-01 to 2021-12-31
  • Development of Interdisciplinary Strategies to Prevent Chronic Opioid Use in Adult Trauma Patients, from 2021-04-01 to 2024-03-31
  • Développement et validation d’une technique pour l’identification et la recommandation d’outils numériques en santé aux patients pour la gestion des maladies chroniques par les pharmaciens communautaires, from 2019-11-01 to 2022-06-30
  • Optimisation de l’usage - Soins pharmaceutiques en première ligne: une communauté de pratique à l'intention des pharmaciens, from 2017-08-22 to 2022-03-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, from 2019-10-01 to 2022-02-28
  • Projet GPS: Évaluation de l'impact de la réorganisation du travail en Groupe de médecine de famille (GMF) sur la Pharmacothérapie et le Soutien à l'autonomie des personnes âgées ayant un trouble neuro-cognitif majeur, from 2019-04-01 to 2022-06-30

Recently finished projects

  • Coûts des maladies cardiovasculaires et des problèmes de santé mentale attribuables aux contraintes psychosociales au travail : Une étude longitudinale de 22 ans auprès de 9 000 cols blancs., from 2016-07-01 to 2021-03-31
  • Définition et validation d'algorithmes de détection des cas de dépression et d'anxiété à l'aide des banques de données médico-administratives (MED-ECHO et RAMQ) du Québec pour les personnes âgées de 65 ans et plus, from 2020-04-01 to 2021-03-31
  • Fonds de soutien sur l'adhésion aux traitements, from 2017-01-01 to 2020-04-30
  • La santé mentale chez des personnes âgées atteintes de diabète de type 2 ou d'hypertension au Québec: dépression, anxiété, déclin cognitif et adhésion aux traitements, from 2019-04-01 to 2021-03-31
  • The Multimorbidity Treatment Burden Questionnaire (MTBQ): translation and validation in French, from 2019-04-01 to 2020-09-30
Data provided by the Université Laval research projects registery