Dr. Line Guénette is a researcher within the Population Health and Health Best Practices Axis of the CHU of Quebec-Laval University Research Centre, as well as an Associate Professor in the Faculty of Pharmacy at Laval University. She is also a clinical pharmacist within the CIUSSS de la Capitale-Nationale. Her research program aims to identify and better understand the issues of drug use, particularly in people with diabetes and the elderly. She is also working to find efficient ways to optimize the use of medicines and to transform professional practices.

She is the recipient of a clinical investigator-junior 1 fellowship from the Fonds de la recherche Québec-Santé (FRQ-S) and of the FRQ-S/Société québécoise d’hypertension artérielle (SQHA) Jacques-de-Champlain Scholarship.

Towards a better understanding of the problems of drug use

Although there are now several effective and well-tolerated drugs to control several chronic diseases and reduce associated complications, problems of poor control are still too common. One of the most important barriers to optimal treatment of chronic diseases is the non-optimal use of drugs by patients and health professionals. The first step to optimize the use of medicines is to better understand the determinants of misuse. Dr. Guénette and her team are achieving this by using large databases of administrative data or surveys of patients and health professionals.

Optimizing the use of medicines

According to recent literature reviews, studies that evaluate the effectiveness of interventions to optimize drug use often have important methodological shortcomings. Moreover, very few of them describe in detail the applied interventions, the targeted determinants and the design of the interventions. It is therefore essential to improve research on the best ways to intervene and on the interventions most likely to be implemented in the Quebec context. It is also crucial to work towards reducing inappropriate practices and implementing new knowledge and activities with proven benefits. To achieve this, Dr. Guénette works closely with clinicians and decision-makers in clinical settings. A project to implement and evaluate the impact of pharmacists’ new activities under Bill 41 is currently underway.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
Québec, Québec
Canada G1S 4L8

Latest news

46 entries « 1 of 10 »

Chartrand M, Lalonde L, Cantin A, Lahaie A, Odobasic B, Tremblay MP, Wazzan D, Gagnon MM, Martin E, Dorais M, Berbiche D, Guenette L

Anticoagulation management services in community pharmacy: Feasibility of implementing a quality improvement programme through a practice-based research network.

Journal Article

J Clin Pharm Ther, 43 (6), pp. 877-887, 2018, ISSN: 0269-4727.

Abstract | Links:

Hudon C, Chouinard MC, Aubrey-Bassler K, Burge F, Doucet S, Ramsden VR, Brodeur M, Bush PL, Couturier Y, Dubois MF, Guenette L, Legare F, Morin P, Poder TG, Poitras ME, Roberge P, Valaitis R, Bighead S, Campbell C, Couture M, Davis B, Deschenes E, Edwards L, Gander S, Gauthier G, Gauthier P, Gibson RJ, Godbout J, Landry G, Longjohn C, Rabbitskin N, Roy DA, Roy J, Sabourin V, Sampalli T, Saulnier A, Spence C, Splane J, Warren M, Young J, Pluye P

Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: an implementation and realist evaluation protocol.

Journal Article

BMJ Open, 8 (11), pp. e026433, 2018.

Abstract | Links:

Leclerc J, Blais C, Rochette L, Hamel D, Guenette L, Poirier P

Trends in Hospital Visits for Generic and Brand-Name Warfarin Users in Québec, Canada: A Population-Based Time Series Analysis.

Journal Article

Am J Cardiovasc Drugs, 2018, ISSN: 1175-3277.

Abstract | Links:

Mercer K, Burns C, Guirguis L, Chin J, Dogba MJ, Dolovich L, Guenette L, Jenkins L, Legare F, McKinnon A, McMurray J, Waked K, Grindrod KA

Physician and Pharmacist Medication Decision-Making in the Time of Electronic Health Records: Mixed-Methods Study.

Journal Article

JMIR Hum Factors, 5 (3), pp. e24, 2018, ISSN: 2292-9495.

Abstract | Links:

Zongo A, Gregoire JP, Moisan J, Guenette L

Measuring adherence to oral antidiabetic multi-drug treatment: Comparative validity of prescription claims-based adherence measures against hospitalization.

Journal Article

Res Social Adm Pharm, 2018, ISSN: 1551-7411.

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Active projects

  • Centre hospitalier universitaire de Québec - CHU de Québec-Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Coûts des maladies cardiovasculaires et des problèmes de santé mentale attribuables aux contraintes psychosociales au travail : Une étude longitudinale de 22 ans auprès de 9 000 cols blancs., Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2020-06-30
  • Réseau-1 Québec (Réseau de recherche en soins et services de santé de première ligne), Subvention, Fonds de recherche du Québec - Santé, Réseau de connaissances du FRQ-S, from 2013-07-01 to 2019-06-30
  • Subvention de fonctionnement 2017-2018, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2017-08-22 to 2020-08-21

Recently finished projects

  • Effet des contraintes psychosociales au travail sur le diabète de type 2: élaboration d'un protocole de recherche pour réaliser une revue systématique de la littérature, Subvention, Centre de recherche sur les soins et les services de première ligne de l'Université Laval, from 2016-07-04 to 2018-01-30
  • Enhancing adherence to adjuvant endocrine therapy among breast cancer survivors: Pilot study of the S.O.I.E. program, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-04-01 to 2018-04-30
  • Evidence-based tools for community pharmacists to detect and intervene on medication non-adherence, Subvention, Fondation Canadienne pour la pharmacie, from 2016-11-12 to 2017-11-01
  • L'adhésion au traitement chez les personnes souffrant de maladies chroniques : étude des facteurs causant la non-adhésion et des interventions pour améliorer l'adhésion chez les diabétiques de type 2, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2014-07-01 to 2018-06-30
  • L'adhésion au traitement chez les personnes souffrant de maladies chroniques : étude des facteurs causant la non-adhésion et des interventions pour améliorer l'adhésion chez les diabétiques de type 2, Subvention, Fonds de recherche du Québec - Santé, Établissement de jeunes chercheurs - Juniors 1, from 2014-10-01 to 2017-09-30
  • PEPS : Projet d'évaluation de la personnalisation des soins pharmaceutiques en soins de longue durée (SLD), Subvention, Fondation Hôpital de Baie-Saint-Paul, from 2017-06-07 to 2018-03-31
  • Projet PEPS – Projet d’évaluation de la personnalisation des soins pharmaceutiques en soins de longue durée (SLD), Subvention, Centre de recherche sur les soins et les services de première ligne de l'Université Laval, from 2017-07-01 to 2018-06-30
  • Recherche pour un vieillissement actif dans la dignité (PEPS), Subvention, Fondation pour les Aînés et l’Innovation Sociale, from 2017-07-06 to 2018-03-31
Data provided by the Université Laval research projects registery