Dr. Michou completed her medical studies at l’Université d’Angers, her Rheumatology residency at l’Université Denis-Diderot-Paris VII and her PhD in Human Genetics at l’Université René-Descartes-Paris V (France). She had in parallel completed a two-year clinical fellowship in fragility bone diseases at the centre Viggo Petersen, Rheumatology department, Lariboisière hospital, Assistance publique-Hôpitaux de Paris, France.

Dr Michou is a clinical investigator at the Centre de Recherche du CHU de Québec-Laval University, rheumatologist at the CHUL, and associate professor at Laval University’s School of Medicine, Quebec. Dr Michou is the principal investigator of several academic research projects in the field of rheumatic diseases, mainly funded by the Fonds de recherche du Québec-Santé, Canadian Institutes of Health research, the Arthritis Society, and the CHU de Québec foundation. She supervises master and PhD students, as well as the clinical research projects of rheumatology and internal medicine residents.

She is the author or coauthor of 53 scientific refereed articles, over  100 oral or poster communications in scientific congresses, and approximately 30 articles of continuing medical education for rheumatologists or family doctors.

Dr. Michou’s research interests are human genetics of bone and joint diseases, particularly Paget’s disease of the bone, rare bone diseases, osteoporosis, Dupuytren’s disease and rheumatoid arthritis. She is the manager of the Biobank and Bank of Data for the Study of Heritable Musculoskeletal Diseases and co-manager of the Biobank and Repository Data for Systemic Autoimmune Rheumatic Diseases.

CHUL
2705, boulevard Laurier
T-R-83
Québec, Québec
Canada G1V 4G2
+1 418-525-4444
+1 418-654-2142
Laetitia.Michou@crchudequ...

Latest news

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Michou L, Orcel P

Has Paget's bone disease become rare?

Journal Article

Joint Bone Spine, 86 (5), pp. 538-541, 2019, ISSN: 1297-319X.

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Nadon V, Molto A, Etcheto A, Bessette L, Michou L, D'Agostino MA, Claudepierre P, Wendling D, Haraoui P, Dougados M

Clinical peripheral enthesitis in the DESIR prospective longitudinal axial spondyloarthritis cohort.

Journal Article

Clin Exp Rheumatol, 37 (4), pp. 561-565, 2019, ISSN: 0392-856X.

Abstract | Links:

Turcotte AF, Grenier-Larouche T, Ung RV, Simonyan D, Carreau AM, Carpentier AC, Mac-Way F, Michou L, Tchernof A, Biertho L, Lebel S, Marceau S, Gagnon C

Effects of Biliopancreatic Diversion on Bone Turnover Markers and Association with Hormonal Factors in Patients with Severe Obesity.

Journal Article

Obes Surg, 29 (3), pp. 990-998, 2019, ISSN: 0960-8923.

Abstract | Links:

Leclerc JT, Michou L, Vaillancourt F, Pelet S, Simonyan D, Belzile EL

Prevalence and Characteristics of Atypical Periprosthetic Femoral Fractures.

Journal Article

J Bone Miner Res, 34 (1), pp. 83-92, 2019, ISSN: 0884-0431.

Abstract | Links:

Numan MS, Jean S, Dessay M, Gagnon E, Amiable N, Brown JP, Michou L

Gene-environment interactions in Paget's disease of bone.

Journal Article

Joint Bone Spine, 86 (3), pp. 373-380, 2019, ISSN: 1297-319X.

Abstract | Links:

Veyssiere M, Perea J, Michou L, Boland A, Caloustian C, Olaso R, Deleuze JF, Cornelis F, Petit-Teixeira E, Chaudru V

A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families.

Journal Article

PLoS ONE, 14 (3), pp. e0213387, 2019.

Abstract | Links:

Silva IAL, Conceicao N, Gagnon E, Caiado H, Brown JP, Gianfrancesco F, Michou L, Leonor Cancela M

Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone.

Journal Article

Biochim Biophys Acta, 1864 (1), pp. 143-151, 2018, ISSN: 0006-3002.

Abstract | Links:

Nguyen P, Julien AS, Bessette L, Fortin PR, Michou L

Sharing Ongoing Care with Primary Care Physicians Opens Up Opportunity for Timelier and Earlier Care by Rheumatologists for Patients with New Inflammatory Polyarthritis.

Journal Article

J Rheumatol, 45 (2), pp. 266-273, 2018, ISSN: 0315-162X.

Abstract | Links:

Michou L

Epigenetics of bone diseases.

Journal Article

Joint Bone Spine, 85 (6), pp. 701-707, 2018, ISSN: 1297-319X.

Abstract | Links:

Paccou J, Michou L, Kolta S, Debiais F, Cortet B, Guggenbuhl P

High bone mass in adults.

Journal Article

Joint Bone Spine, 85 (6), pp. 693-699, 2018, ISSN: 1297-319X.

Abstract | Links:

60 entries « ‹ 1 of 6 › »
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Active projects

  • Caractérisation de biomarqueurs pour une médecine de précision en rhumatologie, Subvention, Fonds de recherche du Québec - Santé, Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, from 2017-07-01 to 2021-06-30
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Clinical validity and clinical utility of a screening test for Paget's disease of bone, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-03-01 to 2020-03-31

Recently finished projects

  • Caractérisation de biomarqueurs génétiques dans les formes familiales de la maladie de Dupuytren, un collaboration Québec-France, Subvention, Société Française de Rhumatologie (France), from 2017-05-01 to 2019-04-30
  • Centre de recherche en endocrinologie, métabolisme et inflammation, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2018-04-30
  • Clinical and molecular heterogeneity of Paget's disease of bone., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2013-10-01 to 2018-09-30
  • Explorations clinique et moléculaire des fractures de stress d'origine génétique, incluant les fractures atypiques des fémurs, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-08-01 to 2019-03-31
  • Mechanisms of osteocytes dysfunction in CKD-minerals and bones desorders, Subvention, Fondation canadienne du rein, Subvention de soutien à la recherche biomédicale, from 2016-07-01 to 2019-06-30
  • Support of Rheumatic Health Units Competition, Subvention, La société d'arthrite, from 2016-09-01 to 2019-08-01
Data provided by the Université Laval research projects registery