Dr. St-Amand completed his doctoral studies at Laval University, and his postdoctoral studies at the University of British Columbia. In 1998, he optimized the SAGE method in his laboratory located in Japan, at the pharmaceutical company Otsuka. He is currently a full professor in the Department of Molecular Medicine at Laval University, and director of the Functional Genomics Laboratory and SAGE platform at the CHU Research Centre of Quebec. He is an expert in genetic engineering and functional genomics.

Dr. St-Amand’s research program aims to characterize the transcriptomes of several tissues and their regulation through physical exercise, a lipid-rich diet, and steroid hormones, in order to identify, clone and characterize functionally the genes of interest that can be used as therapeutic targets for coronary heart disease, obesity, and cancer. Dr. St-Amand’s laboratory is developing genetic engineering methods and bioinformatics programs, particularly for the analysis of functional genomics results. Dr. St-Amand developed the first SAGE platform in Canada. This powerful strategy makes it possible to compare all transcripts, including new genes, to identify the molecular mechanisms responsible for diseases.

Dr. St-Amand and his team are also studying in vitro cells and knockout mice to characterize the functions of candidate genes. These research projects will identify therapeutic targets to, in turn, develop therapeutic treatments for obesity and cardiovascular disease.

CHUL
2705, boulevard Laurier
R-4720
Québec, Québec
Canada G1V 4G2
CHUL
2705, boulevard Laurier
R-4775
Québec, Québec
Canada G1V 4G2

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St-Amand J, Okamura K, Matsumoto K, Shimizu S, Sogawa Y

Characterization of control and immobilized skeletal muscle: an overview from genetic engineering.

Journal Article

FASEB J, 15 (3), pp. 684-92, 2001, ISSN: 0892-6638.

Abstract | Links:

St-Amand J, Prud'Homme D, Moorjani S, Nadeau A, Tremblay A, Bouchard C, Lupien PJ, Després JP

Apolipoprotein E polymorphism and the relationships of physical fitness to plasma lipoprotein-lipid levels in men and women.

Journal Article

Med Sci Sports Exerc, 31 (5), pp. 692-7, 1999, ISSN: 0195-9131.

Abstract | Links:

St-Amand J, Moorjanit S, Lupien PJ, Prud'homme D, Despres JP

The relation of plasma triglyceride, apolipoprotein B, and high-density lipoprotein cholesterol to postheparin lipoprotein lipase activity is dependent on apolipoprotien E polymorphism.

Journal Article

Metabolism, 45 (2), pp. 261-7, 1996, ISSN: 0026-0495.

Abstract | Links:

St-Amand J, Despres JP, Lemieux S, Lamarche B, Moorjani S, Prud'homme D, Bouchard C, Lupien PJ

Does lipoprotein or hepatic lipase activity explain the protective lipoprotein profile of premenopausal women?

Journal Article

Metabolism, 44 (4), pp. 491-8, 1995, ISSN: 0026-0495.

Abstract | Links:

54 entries « 6 of 6 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Roles of exercise-induced gene, SPARC, against sarcopenia: Link between extracellular matrix and mitochondria., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-04-01 to 2021-03-31
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