Dr. St-Amand completed his doctoral studies at Laval University, and his postdoctoral studies at the University of British Columbia. In 1998, he optimized the SAGE method in his laboratory located in Japan, at the pharmaceutical company Otsuka. He is currently a full professor in the Department of Molecular Medicine at Laval University, and director of the Functional Genomics Laboratory and SAGE platform at the CHU Research Centre of Quebec. He is an expert in genetic engineering and functional genomics.

Dr. St-Amand’s research program aims to characterize the transcriptomes of several tissues and their regulation through physical exercise, a lipid-rich diet, and steroid hormones, in order to identify, clone and characterize functionally the genes of interest that can be used as therapeutic targets for coronary heart disease, obesity, and cancer. Dr. St-Amand’s laboratory is developing genetic engineering methods and bioinformatics programs, particularly for the analysis of functional genomics results. Dr. St-Amand developed the first SAGE platform in Canada. This powerful strategy makes it possible to compare all transcripts, including new genes, to identify the molecular mechanisms responsible for diseases.

Dr. St-Amand and his team are also studying in vitro cells and knockout mice to characterize the functions of candidate genes. These research projects will identify therapeutic targets to, in turn, develop therapeutic treatments for obesity and cardiovascular disease.

CHUL
2705, boulevard Laurier
R-4720
Québec, Québec
Canada G1V 4G2
CHUL
2705, boulevard Laurier
R-4775
Québec, Québec
Canada G1V 4G2

Latest news

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66 entries « 1 of 7 »

Ghanemi A, Yoshioka M, St-Amand J

Coronavirus Disease 2019 (COVID-19) Crisis Measures: Health Protective Properties?

Journal Article

Medicines (Basel), 8 (9), 2021.

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Ghanemi A, Yoshioka M, St-Amand J

Coronavirus Disease 2019 (COVID-19) Crisis: Losing Our Immunity When We Need It the Most.

Journal Article

Biology (Basel), 10 (6), 2021.

Abstract | Links:

Ghanemi A, Yoshioka M, St-Amand J

Trefoil Factor Family Member 2: From a High-Fat-Induced Gene to a Potential Obesity Therapy Target.

Journal Article

Metabolites, 11 (8), 2021.

Abstract | Links:

Ghanemi A, Yoshioka M, St-Amand J

High-Fat Diet-Induced Trefoil Factor Family Member 2 (TFF2) to Counteract the Immune-Mediated Damage in Mice.

Journal Article

Animals (Basel), 11 (2), 2021.

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Ghanemi A, Yoshioka M, St-Amand J

Secreted Protein Acidic and Rich in Cysteine as A Regeneration Factor: Beyond the Tissue Repair.

Journal Article

Life (Basel), 11 (1), 2021.

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Ghanemi A, Yoshioka M, St-Amand J

Obese Animals as Models for Numerous Diseases: Advantages and Applications.

Journal Article

Medicina (Kaunas), 57 (5), 2021.

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Ghanemi A, Yoshioka M, St-Amand J

Obesity as a Neuroendocrine Reprogramming.

Journal Article

Medicina (Kaunas), 57 (1), 2021.

Abstract | Links:

Ghanemi A, Melouane A, Yoshioka M, St-Amand J

Exercise Training of Secreted Protein Acidic and Rich in Cysteine (Sparc) KO Mice Suggests That Exercise-Induced Muscle Phenotype Changes Are SPARC-Dependent

Journal Article

Appl Sci (Basel), 10 (24), 2020.

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Ghanemi A, Melouane A, Yoshioka M, St-Amand J

Exercise Training of Secreted Protein Acidic and Rich in Cysteine (Sparc) KO Mice Suggests That Exercise-Induced Muscle Phenotype Changes Are SPARC-Dependent

Journal Article

Appl Sci (Basel), 10 (24), 2020.

Abstract | Links:

Ghanemi A, Yoshioka M, St-Amand J

Regeneration during Obesity: An Impaired Homeostasis.

Journal Article

Animals (Basel), 10 (12), 2020.

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66 entries « 1 of 7 »
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Recently finished projects

  • Roles of exercise-induced gene, SPARC, against sarcopenia: Link between extracellular matrix and mitochondria., from 2014-04-01 to 2021-03-31
Data provided by the Université Laval research projects registery