Jean Bergeron is a physician acting as consultant and clinical scientist at the, Endocrinology and Nephrology Research Unit, Centre de recherche du CHU de Québec – Université Laval, as well as Professor at the Molecular Biology, Medical Biochimistry and Pathology Department, Faculty of Medicine, Laval University. He is member of the Medical Biochimistry Unit (Department of Laboratory Medicine) and chief of the Lipid clinic (Department of Medicine) of the CHU de Québec-Université Laval. He is also Secretary for the Société Québécoise de Lipidologie, Nutrition et Métabolisme (SQLNM), a scientific society from which he received in 2012 a recognition award, Le prix des Fondateurs Jean Davignon et Paul-J. Lupien, for his outstanding contribution in the field of lipidology. As specialist in laboratory medicine and lipidology, he supervises the CHU de Québec – Laval University clinical lipid laboratory performing lipoprotein, lipid and gene analyses.

 

Interest in clinical research

During his career, he has been dedicated to a better understanding of clinical and biological expressions of primary and secondary hyperlipidemia. He has also participated in the development and application of up to date lipid guidelines for clinicians and contributed to the characterization of new metabolic markers related to atherosclerosis and heart disease. He participated to numerous clinical trials using statins and new emergent therapies in lipoprotein metabolism.

 

Actual clinical research

More recently, he is involved in research on statin-generated myopathy, including identification of blood or genetic markers related to statin side effect and development of clinical tools for a better support to patients suffering from this condition. He is involved in the Canadian Familial Hypercholesterolemia registry. Finally, he is principal investigator in several clinical trials using PCSK9 inhibitors, anti-sense oligonucleotides, ANGPTL-3 inhibitors, and in some cases, gene therapy for very severe hypercholesterolemia or patients at very high CV risk for premature atherosclerotic heart disease.

 

CHUL
2705, boulevard Laurier
C-00-224
Québec, Québec
Canada G1V 4G2

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224 entries « 22 of 23 »

Couillard C, Bergeron N, Prud'Homme D, Bergeron J, Tremblay A, Bouchard C, Mauriège P, Després JP

Postprandial triglyceride response in visceral obesity in men.

Journal Article

Diabetes, 47 (6), pp. 953-60, 1998, ISSN: 0012-1797.

Abstract | Links:

Bachvarov DR, Landry M, Pelletier I, Chevrette M, Betard C, Houde I, Bergeron J, Lebel M, Marceau F

Characterization of two polymorphic sites in the human kinin B1 receptor gene: altered frequency of an allele in patients with a history of end-stage renal failure.

Journal Article

J Am Soc Nephrol, 9 (4), pp. 598-604, 1998, ISSN: 1046-6673.

Abstract | Links:

Gaudet D, Vohl MC, Perron P, Tremblay G, Gagné C, Lesiège D, Bergeron J, Moorjani S, Després JP

Relationships of abdominal obesity and hyperinsulinemia to angiographically assessed coronary artery disease in men with known mutations in the LDL receptor gene.

Journal Article

Circulation, 97 (9), pp. 871-7, 1998, ISSN: 0009-7322.

Abstract | Links:

Pérusse L, Rice T, Després JP, Bergeron J, Province MA, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C

Familial resemblance of plasma lipids, lipoproteins and postheparin lipoprotein and hepatic lipases in the HERITAGE Family Study.

Journal Article

Arterioscler Thromb Vasc Biol, 17 (11), pp. 3263-9, 1997, ISSN: 1079-5642.

Abstract | Links:

Echeverry F, Bergeron J, Kaupp W, Guertin C, Arella M

Sequence analysis and expression of the polyhedrin gene of Choristoneura fumiferana cytoplasmic polyhedrosis virus (CfCPV).

Journal Article

Gene, 198 (1-2), pp. 399-406, 1997, ISSN: 0378-1119.

Abstract | Links:

Vohl MC, Moorjani S, Roy M, Gaudet D, Torres AL, Minnich A, Gagné C, Tremblay G, Lambert M, Bergeron J, Couture P, Perron P, Blaichman S, Brun LD, Davignon J, Lupien PJ, Després JP

Geographic distribution of French-Canadian low-density lipoprotein receptor gene mutations in the Province of Quebec.

Journal Article

Clin Genet, 52 (1), pp. 1-6, 1997, ISSN: 0009-9163.

Abstract | Links:

Vohl MC, Gaudet D, Moorjani S, Tremblay G, Perron P, Gagné C, Lesiège D, Bergeron J, Lupien PJ, Després JP

Comparison of the effect of two low-density lipoprotein receptor class mutations on coronary heart disease among French-Canadian patients heterozygous for familial hypercholesterolaemia.

Journal Article

Eur J Clin Invest, 27 (5), pp. 366-73, 1997, ISSN: 0014-2972.

Abstract | Links:

Frank PG, Bergeron J, Emmanuel F, Lavigne JP, Sparks DL, Denèfle P, Rassart E, Marcel YL

Deletion of central alpha-helices in human apolipoprotein A-I: effect on phospholipid association.

Journal Article

Biochemistry, 36 (7), pp. 1798-806, 1997, ISSN: 0006-2960.

Abstract | Links:

Vohl MC, Lamarche B, Bergeron J, Moorjani S, Prud'Homme D, Nadeau A, Tremblay A, Lupien PJ, Bouchard C, Després JP

The MspI polymorphism of the apolipoprotein A-II gene as a modulator of the dyslipidemic state found in visceral obesity.

Journal Article

Atherosclerosis, 128 (2), pp. 183-90, 1997, ISSN: 0021-9150.

Abstract | Links:

Bergeron J, Frank PG, Emmanuel F, Latta M, Zhao Y, Sparks DL, Rassart E, Denèfle P, Marcel YL

Characterization of human apolipoprotein A-I expressed in Escherichia coli.

Journal Article

Biochim Biophys Acta, 1344 (2), pp. 139-52, 1997, ISSN: 0006-3002.

Abstract | Links:

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Recently finished projects

  • Homozygous familial hypercholesterolemia (HoFH) in Canada, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-12-01 to 2020-03-31
Data provided by the Université Laval research projects registery