Dr. Jacques Corbeil focuses on using the latest techniques in bioinformatics and machine learning to assist and facilitate the processes of diagnosis and prognosis determination and to optimize response to treatment. Modern genomic techniques generate a deluge of data that needs to be interpreted using novel bioinformatic approaches. Dr. Corbeil uses state-of-the-art instrumentation and big data analytics to facilitate the interpretation of complex phenotypic data. His research includes investigating how infectious microorganisms interact with their hosts, examining the effects of antibiotics on our microbial flora, exploring how to design small molecules and drugs to interfere with specific microbial functions and integrating omic data in cancer research. Dr. Corbeil operates at the interface of computer and omic sciences.

Dr. Corbeil completed his undergraduate work at Laval University. He obtained his Ph.D. from the University of New South Wales, Sydney, Australia, and received postdoctoral training at the University of California San Diego; continuing on as a faculty member and rising to the rank of Associate Professor until his return to Canada as holder of the Tier 1 Canada Research Chair in Medical Genomics.

CHUL
2705, boulevard Laurier
RC-709
Québec, Québec
Canada G1V 4G2
142 entries « 1 of 15 »

Kpanou R, Osseni MA, Tossou P, Laviolette F, Corbeil J

On the robustness of generalization of drug-drug interaction models.

Journal Article

BMC Bioinformatics, 22 (1), 2021.

Abstract | Links:

Uyar O, Plante PL, Piret J, Venable MC, Carbonneau J, Corbeil J, Boivin G

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis.

Journal Article

Sci Rep, 11 (1), 2021.

Abstract | Links:

Gambino AS, Déraspe M, Álvarez VE, Quiroga MP, Corbeil J, Roy PH, Centrón D

Serratia marcescens SCH909 as reservoir and source of genetic elements related to wide dissemination of antimicrobial resistance mechanisms.

Journal Article

FEMS Microbiol Lett, 368 (14), 2021.

Abstract | Links:

Sirois C, Khoury R, Durand A, Deziel PL, Bukhtiyarova O, Chiu Y, Talbot D, Bureau A, Després P, Gagné C, Laviolette F, Savard AM, Corbeil J, Badard T, Jean S, Simard M

Exploring polypharmacy with artificial intelligence: data analysis protocol.

Journal Article

BMC Med Inform Decis Mak, 21 (1), 2021.

Abstract | Links:

Jungblut AD, Raymond F, Dion MB, Moineau S, Mohit V, Déraspe M, Francovic-Fontaine É, Lovejoy C, Culley AI, Corbeil J, Vincent WF, Nguyen GQ

Genomic diversity and CRISPR-Cas systems in the cyanobacterium Nostoc in the High Arctic.

Journal Article

Environ Microbiol, 23 (6), 2021.

Abstract | Links:

Dion MB, Plante PL, Zufferey E, Shah SA, Corbeil J, Moineau S

Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter.

Journal Article

Nucleic Acids Res, 49 (6), 2021.

Abstract | Links:

Das PS, Gagnon-Turcotte G, Ouazaa K, Bouzid K, Hosseini SN, Bharucha E, Tremblay D, Moineau S, Messaddeq Y, Corbeil J, Gosselin B

The EcoChip 2: An Autonomous Sensor Platform for Multimodal Bio-environmental Monitoring of the Northern Habitat.

Journal Article

Annu Int Conf IEEE Eng Med Biol Soc, 2020 , 2020.

Abstract | Links:

Perkins V, Vignola S, Lessard MH, Plante PL, Corbeil J, Dugat-Bony E, Frenette M, Labrie S

Phenotypic and Genetic Characterization of the Cheese Ripening Yeast .

Journal Article

Front Microbiol, 11 , 2020.

Abstract | Links:

Lemay ML, Otto A, Hamel J, Plante PL, Rousseau GM, Tremblay DM, Shi R, Corbeil J, Gagne SM, Becher D, Moineau S, Maaß S

A Lactococcal Phage Protein Promotes Viral Propagation and Alters the Host Proteomic Response During Infection.

Journal Article

Viruses, 12 (8), 2020.

Abstract | Links:

Kothari C, Osseni MA, Agbo L, Ouellette G, Deraspe M, Laviolette F, Corbeil J, Lambert JP, Diorio C, Durocher F

Machine learning analysis identifies genes differentiating triple negative breast cancers.

Journal Article

Sci Rep, 10 (1), 2020.

Abstract | Links:

142 entries « 1 of 15 »
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Active projects

  • Antimicrobial resistance genes in bioaerosols in Canadian arctic, rural, and urban environments: sources, profiles, transport and fate, from 2019-12-01 to 2023-11-30
  • Calcul Québec, from 2015-04-01 to 2022-03-31
  • Centre de recherche en arthrite (ARThrite), from 2020-11-03 to 2026-04-30
  • Chaire de recherche du Canada en Medical genomics, from 2018-01-01 to 2024-12-31
  • COVID19 persistent symptomatology: an investigation of the metabolomic and proteomic underpinning, from 2021-06-01 to 2022-05-31
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle, from 2020-04-01 to 2023-03-31
  • Développement d'une technologie de contrôle de la qualité des plantes en cours du procédé manufacturier de médicaments en utilisant la spectrométrie de masse à haut débit couplée à des approches en apprentissage automatique , from 2020-03-19 to 2023-03-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3, from 2019-11-01 to 2024-10-31
  • Ecogenomics of mining areas for sustainable Canadian North (GENOSCAN), from 2020-11-01 to 2024-12-31
  • Extreme zooming on intestinal permeability and the western-style diet: Unravelling the role of dietary antigens on the prevalence of cardiometabolic and mental health diseases in the North, from 2020-11-01 to 2024-12-31
  • MAchine learning for diGItal diagnosTICS of antimicrobial resistance, from 2019-10-01 to 2022-09-30
  • Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique, from 2018-04-01 to 2024-03-31
  • Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée, from 2019-04-01 to 2022-03-31
  • UVILUQ: l'utilisation des biopsie liquides pour le monitoring de l'état de santé des écosystèmes marins côtiers, from 2020-07-01 to 2023-06-30

Recently finished projects

  • 3.2 Comprehensive environmental monitoring and valorisation: From molecules to microorganisms, from 2016-04-01 to 2020-03-31
  • Advanced study of unconventional oil behaviour, innovative emergency measures to surface water oil spills: protection of water sources, from 2016-09-30 to 2020-09-29
  • Canada Research Chair in Medical genomics, from 2018-08-01 to 2019-12-31
  • Centre de recherche en arthrite de l'Université Laval, from 2019-01-01 to 2020-01-31
  • Chantier thématique 3: Microbiosmes: Sentinelles de l'environnement et de la santé dans le Nord / 3.0 Budget de coordination du Chantier thématique 3, from 2016-04-01 to 2020-03-31
  • Concert pour la vie, from 2020-11-13 to 2021-03-31
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy, from 2016-07-01 to 2021-06-30
  • La plateforme bio-environnementale EcoChip: Prototypage d'une preuve de concept robuste, from 2020-03-01 to 2021-06-01
  • REinfection in COVid-19 Estimation of Risk (RECOVER), from 2020-06-01 to 2020-09-30
Data provided by the Université Laval research projects registery