Dr. Iwona Rudkowska is an Assistant professor in the Department of Kinesiology at Laval University, and a researcher at the Endocrinology and Nephrology Unit of CHU de Québec Research Center. She completed her university studies in nutrition at McGill University before pursuing postdoctoral training in nutritional genomics at Laval University. Her unique training as a dietitian and researcher, has led her to become a respected young scientist in nutrigenomics, fatty acids, and metabolic health.

Using genomics for the development of personalized nutrition interventions for the prevention and management of type 2 diabetes

Type 2 diabetes is an important public health issue. Several nutritional approaches have already been put in place for the prevention and management of diabetes; nevertheless, a large interindividual variability was observed in response to these interventions. It is therefore essential to understand the genetic architecture of the disease in order to be able to predict the response of an individual to a nutritional therapy. Using the profiles generated by experimental methods such as genetics, transcriptomics and metabolomics, the primary goal of her research is to identify molecular markers of an individual at risk of developing diabetes. This knowledge will allow the development of nutritional interventions adapted to each individual, and thus more effective in the prevention and the management of diabetes.

CHUL
2705, boulevard Laurier
T-4-50
Québec, Québec
Canada G1V 4G2
87 entries « 8 of 9 »

Rudkowska I, Caron-Dorval D, Verreault M, Couture P, Deshaies Y, Barbier O, Vohl MC

PPARalpha L162V polymorphism alters the potential of n-3 fatty acids to increase lipoprotein lipase activity.

Journal Article

Mol Nutr Food Res, 54 (4), pp. 543-50, 2010, ISSN: 1613-4125.

Abstract | Links:

Rudkowska I, Marcotte B, Pilon G, Lavigne C, Marette A, Vohl MC

Fish nutrients decrease expression levels of tumor necrosis factor-alpha in cultured human macrophages.

Journal Article

Physiol Genomics, 40 (3), pp. 189-94, 2010, ISSN: 1094-8341.

Abstract | Links:

Rudkowska I, Vohl MC

Interaction between diets, polymorphisms and plasma lipid levels

Journal Article

Clin Lipidol, 5 (3), pp. 421-438, 2010, ISSN: 1758-4299.

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Rudkowska I, Garenc C, Couture P, Vohl MC

Omega-3 fatty acids regulate gene expression levels differently in subjects carrying the PPARalpha L162V polymorphism.

Journal Article

Genes Nutr, 4 (3), pp. 199-205, 2009, ISSN: 1555-8932.

Abstract | Links:

Rudkowska I

Functional foods for health: focus on diabetes.

Journal Article

Maturitas, 62 (3), pp. 263-9, 2009, ISSN: 0378-5122.

Abstract | Links:

Rudkowska I, Verreault M, Barbier O, Vohl MC

Differences in transcriptional activation by the two allelic (L162V Polymorphic) variants of PPARalpha after Omega-3 fatty acids treatment.

Journal Article

PPAR Res, 2009 , pp. 369602, 2009, ISSN: 1687-4757.

Abstract | Links:

Rudkowska I, Jones PJH

Functional Fats for Weight Control: Conjugated Linoleic Acid, Diacylglycerols, and Medium-Chain Triglycerides

Journal Article

International journal of naturopathic medicine, 4 , pp. 33-38, 2009, ISSN: 1938-0046.

Rudkowska I, AbuMweis SS, Nicolle C, Jones PJ

Cholesterol-lowering efficacy of plant sterols in low-fat yogurt consumed as a snack or with a meal.

Journal Article

J Am Coll Nutr, 27 (5), pp. 588-95, 2008, ISSN: 0731-5724.

Abstract | Links:

Rudkowska I, AbuMweis SS, Nicolle C, Jones PJ

Association between non-responsiveness to plant sterol intervention and polymorphisms in cholesterol metabolism genes: a case-control study.

Journal Article

Appl Physiol Nutr Metab, 33 (4), pp. 728-34, 2008, ISSN: 1715-5312.

Abstract | Links:

Rudkowska I, Jones PJ

Polymorphisms in ABCG5/G8 transporters linked to hypercholesterolemia and gallstone disease.

Journal Article

Nutr Rev, 66 (6), pp. 343-8, 2008, ISSN: 0029-6643.

Abstract | Links:

87 entries « 8 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Dairy bioactive nutrients synergistic effects against inflammation: nutrigenomics and metabolomics approaches., Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2024-03-31
  • Plateforme spécialisée en métabolomique pour les biomarqueurs du risque de diabète associé à la diète, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-08-01 to 2021-07-31
  • Utilisation de profils génomiques pour le développement d'interventions nutritionnelles personnalisées pour le diabète et les facteurs de risques associés, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2019-07-01 to 2024-01-15

Recently finished projects

  • Les maladies cardiométaboliques à l'ère de la révolution numérique, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2020-01-01 to 2020-12-31
Data provided by the Université Laval research projects registery