Hermann Nabi, PhD, HDR, is a regular researcher in the Oncology division at CHU de Québec-Université Laval Research Center and Assistant Professor of Epidemiology at the Department of Social and Preventive Medicine at the Faculty of Medicine of Université Laval. Prior to joining the Center and Université Laval in 2016, Dr. Nabi headed the Research Department of Social and Human Sciences, Epidemiology, Public Health at the Institut National du Cancer(INCa) and was a regular researcher at l’Institut National de la Santé et de la Recherche Médicale(INSERM U.1018) in France.

His team’s work focuses on precision medicine, this emerging medical approach for disease prevention and treatment that takes into account individual differences in genes, environment and lifestyle for each person. With advances in genomics and the advent of new molecular biology technologies, precision medicine is attracting a lot of attention and has become an area of ​​strong international competition. However, despite the large volume and unprecedented rate of gene or biomarker discoveries, relatively few have reached the bedside or contributed to improving the health of populations. This relative poor performance could be explained by the fact that only a small proportion (about 3%) of all published global research addresses issues related to the integration of genomics innovations into health and disease prevention. For this reason, the ultimate goal of Dr. Nabi’s team is to generate evidence to facilitate a successful and responsible integration of precision medicine innovations into health care and prevention, particularly for cancer.

To achieve this goal, his work is organized around three main objectives:

1) Characterize the mechanisms and organizational implications of the progressive adoption of innovations in precision medicine in oncology,

2) Evaluate the impact of diagnostic and therapeutic innovations in precision medicine on the quality of life and clinical outcomes of cancer patients and the effectiveness for the health system,

3) Develop and evaluate intervention methods to support the integration of innovations, which takes into account patients and populations’ preferences, economic, accessibility and impact issues, in a knowledge transfer perspective.

The originality of this research program lies in its interdisciplinary approach, which combines a variety of skills and methodological tools to answer questions that are at the interface of several scientific fields. This approach proposes a new way of approaching translational research (the transfer of discoveries from laboratory to bedside), through the use of concepts, models and methods  the human and social sciences, epidemiology, public health, health services research and implementation science.

Hôpital Saint-Sacrement
1050, Chemin Ste-Foy
J0-01
Québec, Qc
Canada G1S 4L8

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Nabi H, Dorval M, Chiquette J, Simard J

Increased Use of BRCA Mutation Test in Unaffected Women Over the Period 2004-2014 in the U.S.: Further Evidence of the "Angelina Jolie Effect"?

Journal Article

Am J Prev Med, 53 (5), pp. e195-e196, 2017, ISSN: 0749-3797.

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Lemogne C, Meneton P, Wiernik E, Quesnot A, Consoli SM, Ducimetiere P, Nabi H, Empana JP, Hoertel N, Limosin F, Goldberg M, Zins M

When Blue-Collars Feel Blue: Depression and Low Occupational Grade as Synergistic Predictors of Incident Cardiac Events in Middle-Aged Working Individuals.

Journal Article

Circ Cardiovasc Qual Outcomes, 10 (2), 2017, ISSN: 1941-7713.

Abstract | Links:

Wiernik E, Lemogne C, Thomas F, Perier MC, Guibout C, Nabi H, Laurent S, Pannier B, Boutouyrie P, Jouven X, Empana JP

Perceived stress, common carotid intima media thickness and occupational status: The Paris Prospective Study III.

Journal Article

Int J Cardiol, 221 , pp. 1025-30, 2016, ISSN: 0167-5273.

Abstract | Links:

Azevedo Da Silva M, Balkau B, Roussel R, Tichet J, Fumeron F, Fagherazzi G, Nabi H, D.E.S.I.R. study group

Longitudinal association of antidepressant medication use with metabolic syndrome: Results of a 9-year follow-up of the D.E.S.I.R. cohort study.

Journal Article

Psychoneuroendocrinology, 74 , pp. 34-45, 2016, ISSN: 0306-4530.

Abstract | Links:

Berthet N, Berling C, Nabi H, Woto Gaye G, Toure Kane C, Diop-Ndiaye H, Koumakpayi IH, Engohan Aloghe C, Bisvigou U, Didi Coulibaly J, Faye Kette H, Koffi E, Ekra D, Moussavou Boundzanga P, Labouba I, NJouom R, Tebeu PM, Sandjong I, Atangana PA, N'Kegoum B, Rakoto-Andrianarivelo M, Rakotomalala FA, Randrianjafisamindrakotroka N, Andriamampionona TF, Ratovohery A, Sastre-Garau X, Diop M

COFAC-Col: A Cervical Cancer Control Networking Initiative in Five French-Speaking African Countries.

Journal Article

Cancer Epidemiol Biomarkers Prev, 25 (6), pp. 1004-5, 2016, ISSN: 1055-9965.

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Nabi H, Estaquio C, Auleley GR

Smoking and mortality--beyond established causes.

Journal Article

N Engl J Med, 372 (22), pp. 2169, 2015, ISSN: 0028-4793.

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Azevedo Da Silva M, Lemogne C, Melchior M, Zins M, Van Der Waerden J, Consoli SM, Goldberg M, Elbaz A, Singh-Manoux A, Nabi H

Excess non-psychiatric hospitalizations among employees with mental disorders: a 10-year prospective study of the GAZEL cohort.

Journal Article

Acta Psychiatr Scand, 131 (4), pp. 307-17, 2015, ISSN: 0001-690X.

Abstract | Links:

Hinnouho GM, Czernichow S, Dugravot A, Nabi H, Brunner EJ, Kivimaki M, Singh-Manoux A

Metabolically healthy obesity and the risk of cardiovascular disease and type 2 diabetes: the Whitehall II cohort study.

Journal Article

Eur Heart J, 36 (9), pp. 551-9, 2015, ISSN: 0195-668X.

Abstract | Links:

Lemogne C, Schuster JP, Levenstein S, Melchior M, Nabi H, Ducimetiere P, Limosin F, Goldberg M, Zins M, Consoli SM

Hostility and the risk of peptic ulcer in the GAZEL cohort.

Journal Article

Health Psychol, 34 (2), pp. 181-5, 2015, ISSN: 0278-6133.

Abstract | Links:

Da Silva MA, Dugravot A, Balkau B, Roussel R, Fumeron F, Elbaz A, Canonico M, Singh-Manoux A, Nabi H, D.E.S.I.R. Study Group

Antidepressant medication use and trajectories of fasting plasma glucose, glycated haemoglobin, β-cell function and insulin sensitivity: a 9-year longitudinal study of the D.E.S.I.R. cohort.

Journal Article

Int J Epidemiol, 44 (6), pp. 1927-40, 2015, ISSN: 0300-5771.

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83 entries « 2 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Conseil génétique concernant le risque héréditaire de cancer du sein: Comment améliorer l’offre de services pour préserver la qualité de vie et la satisfaction des femmes potentiellement à risque?, Subvention, Fondation de l'Université Laval, from 2019-01-01 to 2020-03-31
  • Enjeux de l’intégration de la Médecine de Précision en Oncologie : mieux comprendre pour mieux agir (teMPO), Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2018-07-01 to 2022-06-30
  • Personalized Risk Assesment for Prevention and Early Detection of Breast Cancer : Integration and Implementation (PERSPECTIVE II), Subvention, Génome Canada, Projets de recherche appliquée à grande échelle, from 2017-11-01 to 2022-03-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-10-01 to 2022-02-28
  • Programme de soutien aux nouveaux chercheurs, Subvention, Université Laval - démarrage nouveau chercheur, Soutien facultaire aux jeunes chercheurs de la Faculté de médecine, from 2018-07-01 to 2020-06-30

Recently finished projects

  • Enjeux de l'intégration de la médecine de précision en oncologie: mieux comprendre pour mieux agir a été acceptée , Subvention, Fondation du CHU de Québec, from 2019-01-09 to 2019-03-31
  • Fonds de démarrage. Hermann Nabi , Subvention, Fondation du CHU de Québec, from 2018-09-18 to 2019-03-31
  • Inégalités sociales dans les trajectoires d'usage des traitements oraux pour le cancer du sein : Une comparaison France - Québec, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2017-04-01 to 2019-03-31
  • Préférences sociétales concernant la divulgation des découvertes fortuites issues de la génomique clinique : Perspectives de patients atteints de cancer et de la population générale, Subvention, Conseil de recherches en sciences humaines du Canada, Programme Savoir : Subventions de développement Savoir, from 2017-06-01 to 2019-09-30
Data provided by the Université Laval research projects registery