Hermann Nabi, PhD, HDR, is a regular researcher in the Oncology division at CHU de Québec-Université Laval Research Center and Assistant Professor of Epidemiology at the Department of Social and Preventive Medicine at the Faculty of Medicine of Université Laval. Prior to joining the Center and Université Laval in 2016, Dr. Nabi headed the Research Department of Social and Human Sciences, Epidemiology, Public Health at the Institut National du Cancer(INCa) and was a regular researcher at l’Institut National de la Santé et de la Recherche Médicale(INSERM U.1018) in France.

His team’s work focuses on precision medicine, this emerging medical approach for disease prevention and treatment that takes into account individual differences in genes, environment and lifestyle for each person. With advances in genomics and the advent of new molecular biology technologies, precision medicine is attracting a lot of attention and has become an area of ​​strong international competition. However, despite the large volume and unprecedented rate of gene or biomarker discoveries, relatively few have reached the bedside or contributed to improving the health of populations. This relative poor performance could be explained by the fact that only a small proportion (about 3%) of all published global research addresses issues related to the integration of genomics innovations into health and disease prevention. For this reason, the ultimate goal of Dr. Nabi’s team is to generate evidence to facilitate a successful and responsible integration of precision medicine innovations into health care and prevention, particularly for cancer.

To achieve this goal, his work is organized around three main objectives:

1) Characterize the mechanisms and organizational implications of the progressive adoption of innovations in precision medicine in oncology,

2) Evaluate the impact of diagnostic and therapeutic innovations in precision medicine on the quality of life and clinical outcomes of cancer patients and the effectiveness for the health system,

3) Develop and evaluate intervention methods to support the integration of innovations, which takes into account patients and populations’ preferences, economic, accessibility and impact issues, in a knowledge transfer perspective.

The originality of this research program lies in its interdisciplinary approach, which combines a variety of skills and methodological tools to answer questions that are at the interface of several scientific fields. This approach proposes a new way of approaching translational research (the transfer of discoveries from laboratory to bedside), through the use of concepts, models and methods  the human and social sciences, epidemiology, public health, health services research and implementation science.

Hôpital Saint-Sacrement
1050, Chemin Ste-Foy
J0-01
Québec, Qc
Canada G1S 4L8

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83 entries « 1 of 9 »

Cleophat JE, Marin A, Pelletier S, Joly Y, Gagnon P, Dery A, Chiquette J, Gagnon B, Roy L, Bitzas V, Nabi H, Dorval M

What do cancer patients' relatives think about addressing cancer family history and performing genetic testing in palliative care?

Journal Article

Eur J Hum Genet, 2019, ISSN: 1018-4813.

Abstract | Links:

Oudanonh T, Nabi H, Ennour-Idrissi K, Lemieux J, Diorio C

Progesterone receptor status modifies the association between body mass index and prognosis in women diagnosed with estrogen receptor positive breast cancer.

Journal Article

Int J Cancer, 2019, ISSN: 0020-7136.

Abstract | Links:

Cleophat JE, Pelletier S, Joly Y, Gagnon P, Dery A, Marin A, Chiquette J, Gagnon B, Roy L, Bitzas V, Nabi H, Dorval M

Addressing cancer family history at the end of life: How frequent, relevant, and feasible is it? A survey of palliative care providers.

Journal Article

Palliat Med, 33 (7), pp. 856-858, 2019, ISSN: 0269-2163.

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Antoniou A, Anton-Culver H, Borowsky A, Broeders M, Brooks J, Chiarelli A, Chiquette J, Cuzick J, Delaloge S, Devilee P, Dorval M, Easton D, Eisen A, Eklund M, Eloy L, Esserman L, Garcia-Closas M, Goldgar D, Hall P, Knoppers BM, Kraft P, La Croix A, Madalensky L, Mavaddat N, Mittman N, Nabi H, Olopade O, Pashayan N, Schmidt M, Shieh Y, Simard J, Stover-Fiscallini A, Tice JA, Van't Veer L, Wenger N, Wolfson M, Yau C, Ziv E

A response to "Personalised medicine and population health: breast and ovarian cancer".

Journal Article

Hum Genet, 138 (3), pp. 287-289, 2019, ISSN: 0340-6717.

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Nabi H, Provencher L, Diorio C

RE: Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424).

Journal Article

J Natl Cancer Inst, 110 (12), pp. 1422-1423, 2018, ISSN: 0027-8874.

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Wiernik E, Meneton P, Empana JP, Siemiatycki J, Hoertel N, Vulser H, Nabi H, Limosin F, Czernichow S, Goldberg M, Ozguler A, Zins M, Lemogne C

Cardiovascular risk goes up as your mood goes down: Interaction of depression and socioeconomic status in determination of cardiovascular risk in the CONSTANCES cohort.

Journal Article

Int J Cardiol, 262 , pp. 99-105, 2018, ISSN: 0167-5273.

Abstract | Links:

Nabi H, Diorio C

Body mass index and clinical outcomes in trastuzumab-treated metastatic breast cancer patients: An alternative explanation for the lack of association.

Journal Article

Breast, 39 , pp. 150-151, 2018, ISSN: 0960-9776.

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Nabi H, Guertin JR, Talbot D, Diorio C

Body-mass index and metastatic melanoma outcomes.

Journal Article

Lancet Oncol, 19 (5), pp. e226, 2018, ISSN: 1470-2045.

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Cleophat JE, Nabi H, Pelletier S, Bouchard K, Dorval M

What characterizes cancer family history collection tools? A critical literature review.

Journal Article

Curr Oncol, 25 (4), pp. e335-e350, 2018, ISSN: 1198-0052.

Abstract | Links:

Kelly DM, Estaquio C, Leon C, Arwidson P, Nabi H

Temporal trend in socioeconomic inequalities in the uptake of cancer screening programmes in France between 2005 and 2010: results from the Cancer Barometer surveys.

Journal Article

BMJ Open, 7 (12), pp. e016941, 2017.

Abstract | Links:

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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Conseil génétique concernant le risque héréditaire de cancer du sein: Comment améliorer l’offre de services pour préserver la qualité de vie et la satisfaction des femmes potentiellement à risque?, Subvention, Fondation de l'Université Laval, from 2019-01-01 to 2020-03-31
  • Enjeux de l’intégration de la Médecine de Précision en Oncologie : mieux comprendre pour mieux agir (teMPO), Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2018-07-01 to 2022-06-30
  • Personalized Risk Assesment for Prevention and Early Detection of Breast Cancer : Integration and Implementation (PERSPECTIVE II), Subvention, Génome Canada, Projets de recherche appliquée à grande échelle, from 2017-11-01 to 2022-03-31
  • Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-10-01 to 2022-02-28
  • Programme de soutien aux nouveaux chercheurs, Subvention, Université Laval - démarrage nouveau chercheur, Soutien facultaire aux jeunes chercheurs de la Faculté de médecine, from 2018-07-01 to 2020-06-30

Recently finished projects

  • Enjeux de l'intégration de la médecine de précision en oncologie: mieux comprendre pour mieux agir a été acceptée , Subvention, Fondation du CHU de Québec, from 2019-01-09 to 2019-03-31
  • Fonds de démarrage. Hermann Nabi , Subvention, Fondation du CHU de Québec, from 2018-09-18 to 2019-03-31
  • Inégalités sociales dans les trajectoires d'usage des traitements oraux pour le cancer du sein : Une comparaison France - Québec, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2017-04-01 to 2019-03-31
  • Préférences sociétales concernant la divulgation des découvertes fortuites issues de la génomique clinique : Perspectives de patients atteints de cancer et de la population générale, Subvention, Conseil de recherches en sciences humaines du Canada, Programme Savoir : Subventions de développement Savoir, from 2017-06-01 to 2019-09-30
Data provided by the Université Laval research projects registery