Dr. Guy Boivin is a professor in the Department of Microbiology-Immunology and Infectious Diseases of the Faculty of Medicine at Laval University. He holds the Canada Research Chair in Emerging Viruses and Antiviral Resistance, as well as a “Foundation” grant from the Canadian Institutes of Health Research (CIHR). He is also co-principal investigator of major grants, such as the FPQIS ($ 12M), for the development of new generation influenza vaccine in the elderly.

Dr. Boivin is the author or co-author of 300 scientific publications and 350 presentations at various international conferences and symposia. He has also contributed to the creation of 9 patents and is co-founder of the company Signia Therapeutics, specializing in the repositioning of drugs to counter viral respiratory infections. He is also the director of an NC3 laboratory that will be operational in 2018, which will expand the various research projects to highly pathogenic respiratory viruses, such as avian influenza viruses (H5N1, H7N9) and other emerging respiratory viruses. (MERS-CoV).

His research program focuses on the diagnosis, pathogenesis, and treatment of viral infections. He studies herpetic and respiratory viruses, including those causing the flu (including avian flu). More recently, he has also been interested in the Zika virus. He uses cell and molecular biology technologies, as well as different animal models to develop rapid diagnostic tests, evaluate new antiviral molecules, elucidate mechanisms of resistance to antiviral agents, and generate new vaccines. He has developed several multicenter studies to assess the clinical and epidemiological impact of emerging respiratory viruses. He collaborates with several fundamental and clinical research groups as well as various pharmaceutical companies. His work will have a significant impact on the diagnosis, treatment, and prevention of frequent and potentially life-threatening viral infections in certain groups of individuals.

CHUL
2705, boulevard Laurier
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Québec, Québec
Canada G1V 4G2
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Jones ST, Cagno V, Janecek M, Ortiz D, Gasilova N, Piret J, Gasbarri M, Constant DA, Han Y, Vukovic L, Kral P, Kaiser L, Huang S, Constant S, Kirkegaard K, Boivin G, Stellacci F, Tapparel C

Modified cyclodextrins as broad-spectrum antivirals.

Journal Article

Sci Adv, 6 (5), pp. eaax9318, 2020, ISSN: 2375-2548.

Abstract | Links:

Abed Y, Fage C, Checkmahomed L, Venable MC, Boivin G

Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice.

Journal Article

Antiviral Res, 179 , pp. 104807, 2020, ISSN: 0166-3542.

Abstract | Links:

Enlow W, Piret J, Boivin G

Droplet Digital PCR and Immunohistochemistry Techniques to Detect Zika Virus in the Central Nervous System of Mice.

Journal Article

Methods Mol Biol, 2142 , pp. 41-57, 2020, ISSN: 1064-3745.

Abstract | Links:

Boivin G, Rosa-Calatrava M, Lina B

Novel antiviral compounds and combination therapy for influenza viruses.

Journal Article

Virologie, 23 (6), pp. 325-328, 2019, ISSN: 1267-8694.

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Boivin G, Rosa-Calatrava M, Lina B

Novel antiviral compounds and combination therapy for influenza viruses.

Journal Article

Virologie, 23 (6), pp. 32-35, 2019, ISSN: 1267-8694.

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Baz M, M'hamdi Z, Carbonneau J, Lavigne S, Couture C, Abed Y, Boivin G

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus.

Journal Article

Sci Rep, 9 (1), pp. 16616, 2019, ISSN: 2045-2322.

Abstract | Links:

Dubois J, Pizzorno A, Cavanagh MH, Padey B, Nicolas de Lamballerie C, Uyar O, Venable MC, Carbonneau J, Traversier A, Julien T, Lavigne S, Couture C, Lina B, Hamelin ME, Terrier O, Rosa-Calatrava M, Boivin G

Strain-Dependent Impact of G and SH Deletions Provide New Insights for Live-Attenuated HMPV Vaccine Development.

Journal Article

Vaccines (Basel), 7 (4), 2019, ISSN: 2076-393X.

Abstract | Links:

Ramendra R, Isnard S, Lin J, Fombuena B, Ouyang J, Mehraj V, Zhang Y, Finkelman M, Costiniuk C, Lebouche B, Chartrand-Lefebvre C, Durand M, Tremblay C, Ancuta P, Boivin G, Routy JP

CMV seropositivity is associated with increased microbial translocation in people living with HIV and uninfected controls.

Journal Article

Clin Infect Dis, 2019, ISSN: 1058-4838.

Abstract | Links:

Boivin G, Lina B

Influenza virus epidemiology: a permanent vaccine challenge.

Journal Article

Virologie, 23 (5), pp. 271-276, 2019, ISSN: 1267-8694.

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Piret J, Schibler M, Pham VD, Hantz S, Giannotti F, Masouridi-Levrat S, Kaiser L, Goyette N, Alain S, Shi R, Boivin G

Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis.

Journal Article

J Infect Dis, 220 (8), pp. 1302-1306, 2019, ISSN: 0022-1899.

Abstract | Links:

338 entries « 2 of 34 »
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Active projects

  • A research program on the pathogenesis, treatment and prevention of respiratory and herpes viruses, Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2016-07-01 to 2023-06-30
  • Canadian Immunization Research Network, Subvention, Instituts de recherche en santé du Canada, Réseau canadien de recherche sur l’immunisation, from 2014-06-01 to 2021-12-31
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche en infectiologie, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2024-11-06
  • How to better manage infectious diseases in ER by triage with molecular mini-panels for the rapid detection of highly transmissible pathogens, Subvention, Consortium québécois sur la découverte du médicament, from 2018-10-01 to 2022-09-30
  • Innovative therapeutic approaches for the 2019-novel coronavirus, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Possibilité de financement canadienne pour une intervention de recherche rapide contre la maladie à coronavirus 2019 (COVID-19), from 2020-02-01 to 2022-01-31
  • Sentinel surveillance, viral shedding, clinical characteristics and outcomes of confirmed and suspected hospitalized cases of COVID-19/SARS-CoV-2 infection in the Canadian Immunization Research Network (CIRN), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Possibilité de financement pour une intervention de recherche rapide contre la COVID-19, from 2020-04-01 to 2021-03-31
  • Sex as a Biological Variable Supplement - Innovative therapeutic approaches for the 2019-novel coronavirus, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Financement supplémentaire pour l’intégration du sexe comme variable biologique dans l’intervention de recherche rapide contre la COVID-19, from 2020-05-01 to 2021-03-31

Recently finished projects

  • Chaire de recherche du Canada sur les virus en émergence et la résistance aux antiviraux, Subvention, Secrétariat des Chaires de recherche du Canada, Chaires de recherche du Canada - Fonctionnement, from 2013-07-01 to 2020-06-30
Data provided by the Université Laval research projects registery