Dr. Guy Boivin is a professor in the Department of Microbiology-Immunology and Infectious Diseases of the Faculty of Medicine at Laval University. He holds the Canada Research Chair in Emerging Viruses and Antiviral Resistance, as well as a “Foundation” grant from the Canadian Institutes of Health Research (CIHR). He is also co-principal investigator of major grants, such as the FPQIS ($ 12M), for the development of new generation influenza vaccine in the elderly.

Dr. Boivin is the author or co-author of 300 scientific publications and 350 presentations at various international conferences and symposia. He has also contributed to the creation of 9 patents and is co-founder of the company Signia Therapeutics, specializing in the repositioning of drugs to counter viral respiratory infections. He is also the director of an NC3 laboratory that will be operational in 2018, which will expand the various research projects to highly pathogenic respiratory viruses, such as avian influenza viruses (H5N1, H7N9) and other emerging respiratory viruses. (MERS-CoV).

His research program focuses on the diagnosis, pathogenesis, and treatment of viral infections. He studies herpetic and respiratory viruses, including those causing the flu (including avian flu). More recently, he has also been interested in the Zika virus. He uses cell and molecular biology technologies, as well as different animal models to develop rapid diagnostic tests, evaluate new antiviral molecules, elucidate mechanisms of resistance to antiviral agents, and generate new vaccines. He has developed several multicenter studies to assess the clinical and epidemiological impact of emerging respiratory viruses. He collaborates with several fundamental and clinical research groups as well as various pharmaceutical companies. His work will have a significant impact on the diagnosis, treatment, and prevention of frequent and potentially life-threatening viral infections in certain groups of individuals.

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Ramendra R, Isnard S, Lin J, Fombuena B, Ouyang J, Mehraj V, Zhang Y, Finkelman M, Costiniuk C, Lebouche B, Chartrand-Lefebvre C, Durand M, Tremblay C, Ancuta P, Boivin G, Routy JP

Cytomegalovirus Seropositivity Is Associated With Increased Microbial Translocation in People Living With Human Immunodeficiency Virus and Uninfected Controls.

Journal Article

Clin Infect Dis, 71 (6), pp. 1438-1446, 2020, ISSN: 1058-4838.

Abstract | Links:

Nicolas de Lamballerie C, Pizzorno A, Dubois J, Padey B, Julien T, Traversier A, Carbonneau J, Orcel E, Lina B, Hamelin ME, Roche M, Textoris J, Boivin G, Legras-Lachuer C, Terrier O, Rosa-Calatrava M

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples.

Journal Article

J Infect Dis, 2020, ISSN: 0022-1899.

Abstract | Links:

Lees C, Godin J, McElhaney JE, McNeil SA, Loeb M, Hatchette TF, LeBlanc J, Bowie W, Boivin G, McGeer A, Poirier A, Powis J, Semret M, Webster D, Andrew MK

Frailty Hinders Recovery From Influenza and Acute Respiratory Illness in Older Adults.

Journal Article

J Infect Dis, 222 (3), pp. 428-437, 2020, ISSN: 0022-1899.

Abstract | Links:

Zarrouk K, Pham VD, Piret J, Shi R, Boivin G

Hypersusceptibility of Human Cytomegalovirus to Foscarnet Induced by Mutations in Helices K and P of the Viral DNA Polymerase.

Journal Article

Antimicrob Agents Chemother, 64 (4), 2020, ISSN: 0066-4804.

Abstract | Links:

Piret J, Boivin G

Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis.

Journal Article

Clin Microbiol Rev, 33 (2), 2020, ISSN: 0893-8512.

Abstract | Links:

LeBlanc J, ElSherif M, Ye L, MacKinnon-Cameron D, Ambrose A, Hatchette TF, Lang AL, Gillis HD, Martin I, Demczuk WH, LaFerriere C, Andrew MK, Boivin G, Bowie W, Green K, Johnstone J, Loeb M, McCarthy A, McGeer A, Semret M, Trottier S, Valiquette L, Webster D, McNeil SA

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015.

Journal Article

BMJ Open Respir Res, 7 (1), 2020, ISSN: 2052-4439.

Abstract | Links:

Pilaev M, Shen Y, Carbonneau J, Venable MC, Rheaume C, Lavigne S, Couture C, Guarne A, Hamelin ME, Boivin G

Evaluation of pre- and post-fusion Human metapneumovirus F proteins as subunit vaccine candidates in mice.

Journal Article

Vaccine, 38 (9), pp. 2122-2127, 2020, ISSN: 0264-410X.

Abstract | Links:

Ogonczyk Makowska D, Hamelin ME, Boivin G

Engineering of Live Chimeric Vaccines against Human Metapneumovirus.

Journal Article

Pathogens, 9 (2), 2020, ISSN: 2076-0817.

Abstract | Links:

LeBlanc JJ, ElSherif M, Mulpuru S, Warhuus M, Ambrose A, Andrew M, Boivin G, Bowie W, Chit A, Dos Santos G, Green K, Halperin SA, Hatchette TF, Ibarguchi B, Johnstone J, Katz K, Langley JM, Lagace-Wiens P, Loeb M, Lund A, MacKinnon-Cameron D, McCarthy A, McElhaney JE, McGeer A, Poirier A, Powis J, Richardson D, Semret M, Shinde V, Smyth D, Trottier S, Valiquette L, Webster D, Ye L, McNeil SA

Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults.

Journal Article

J Med Microbiol, 69 (2), pp. 256-264, 2020, ISSN: 0022-2615.

Abstract | Links:

Mandon ED, Pizzorno A, Traversier A, Champagne A, Hamelin ME, Lina B, Boivin G, Dejean E, Rosa-Calatrava M, Jawhari A

Novel calixarene-based surfactant enables low dose split inactivated vaccine protection against influenza infection.

Journal Article

Vaccine, 38 (2), pp. 278-287, 2020, ISSN: 0264-410X.

Abstract | Links:

338 entries « 1 of 34 »
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Active projects

  • A research program on the pathogenesis, treatment and prevention of respiratory and herpes viruses, Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2016-07-01 to 2023-06-30
  • Canadian Immunization Research Network, Subvention, Instituts de recherche en santé du Canada, Réseau canadien de recherche sur l’immunisation, from 2014-06-01 to 2021-12-31
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche en infectiologie, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2024-11-06
  • How to better manage infectious diseases in ER by triage with molecular mini-panels for the rapid detection of highly transmissible pathogens, Subvention, Consortium québécois sur la découverte du médicament, from 2018-10-01 to 2022-09-30
  • Innovative therapeutic approaches for the 2019-novel coronavirus, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Possibilité de financement canadienne pour une intervention de recherche rapide contre la maladie à coronavirus 2019 (COVID-19), from 2020-02-01 to 2022-01-31
  • Sentinel surveillance, viral shedding, clinical characteristics and outcomes of confirmed and suspected hospitalized cases of COVID-19/SARS-CoV-2 infection in the Canadian Immunization Research Network (CIRN), Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Possibilité de financement pour une intervention de recherche rapide contre la COVID-19, from 2020-04-01 to 2021-03-31
  • Sex as a Biological Variable Supplement - Innovative therapeutic approaches for the 2019-novel coronavirus, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Financement supplémentaire pour l’intégration du sexe comme variable biologique dans l’intervention de recherche rapide contre la COVID-19, from 2020-05-01 to 2021-03-31

Recently finished projects

  • Chaire de recherche du Canada sur les virus en émergence et la résistance aux antiviraux, Subvention, Secrétariat des Chaires de recherche du Canada, Chaires de recherche du Canada - Fonctionnement, from 2013-07-01 to 2020-06-30
Data provided by the Université Laval research projects registery