Gaétan Laroche is a professor at the Department of Materials Engineering of the Faculty of Science and Engineering at Laval University. He is a member of the Centre de Recherche sur les Matériaux Avancés (CERMA) at Laval University and of Quebec Center on Advanced Materials (QCAM). His research focuses on the surface modification of biomedical materials to improve their biocompatibility. Dr. Laroche is internationally renowned for his work on surface modification of materials that make use of the use of gaseous plasmas. More specifically, he is developing surface modification strategies for vascular and orthopedic biomaterials to improve their biocompatibility. Dr. Laroche was awarded the title of Fellow of Biomaterials Science and Engineering (FBSE) from the International Union of Societies of Biomaterials Science and Engineering. Engaged both academically and scientifically, Dr. Laroche sat on several scientific research evaluation committees and was a member of the executive committee responsible for organizing the prestigious World Biomaterials Congress held in Montreal in May 2016. He was also awarded the joint prize given by the Club des Ambassadeurs of the Palais des congrès de Montréal and the Fonds de recherche du Québec and was chosen as the personality of the week by Le Soleil / Radio-Canada.

Towards materials with better blood compatibility
Today, cardiovascular disease is one of the leading causes of death in the world, killing 17 million people a year. For about 1.5 million patients, the best solution is to use a vascular substitute to replace obstructed blood vessels. In this context, Dr. Laroche’s team seeks to develop surface modification strategies for synthetic materials to allow better integration with the physiological medium.

Fighting against infection of orthopedic prostheses infection
Infection is one of the main problems when implanting orthopedic prostheses. The modification of the chemical composition of orthopedic materials makes it possible to improve their interactions with cells of the human body and to actively combat any bacterial colonization.

Hôpital Saint-François d'Assise
10, rue de l'Espinay
E0-175
Québec, Québec
Canada G1L 3L5
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Elkhodiry MA, Boulanger MD, Bashth O, Tanguay JF, Laroche G, Hoesli CA

Isolating and expanding endothelial progenitor cells from peripheral blood on peptide-functionalized polystyrene surfaces.

Journal Article

Biotechnol Bioeng, 2019, ISSN: 0006-3592.

Abstract | Links:

Duran IR, Laroche G

Water drop-surface interactions as the basis for the design of anti-fogging surfaces: Theory, practice, and applications trends.

Journal Article

Adv Colloid Interface Sci, 263 , pp. 68-94, 2019, ISSN: 0001-8686.

Abstract | Links:

Royer C, Begin AG, Plawinski L, Levesque L, Durrieu MC, Laroche G

Validation of reference genes for real-time PCR of cord blood mononuclear cells, differentiating endothelial progenitor cells, and mature endothelial cells.

Journal Article

Exp Cell Res, 370 (2), pp. 389-398, 2018, ISSN: 0014-4827.

Abstract | Links:

Amri A, Laroche G, Chakfe N, Heim F

Fibrous composite material for textile heart valve design: in vitro assessment.

Journal Article

Biomed Tech (Berl), 63 (3), pp. 221-230, 2018, ISSN: 0013-5585.

Abstract | Links:

Bilem I, Plawinski L, Chevallier P, Ayela C, Sone ED, Laroche G, Durrieu MC

The spatial patterning of RGD and BMP-2 mimetic peptides at the subcellular scale modulates human mesenchymal stem cells osteogenesis.

Journal Article

J Biomed Mater Res A, 106 (4), pp. 959-970, 2018, ISSN: 1549-3296.

Abstract | Links:

Le QC, Lefevre T, C-Gaudreault R, Laroche G, Auger M

Transdermal diffusion, spatial distribution and physical state of a potential anticancer drug in mouse skin as studied by diffusion and spectroscopic techniques

Journal Article

Biomed Spectrosc Imaging, 7 (1-2), pp. 47-61, 2018, ISSN: 2212-8794.

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Anooshehpoura F, Turgeon S, Cloutier M, Mantovani D, Laroche G

Optical emission spectroscopy as a process-monitoring tool in plasma enhanced chemical vapor deposition of amorphous carbon coatings - multivariate statistical modelling

Journal Article

Thin Solid Films, 649 , pp. 106-114, 2018, ISSN: 0040-6090.

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Vallade J, Turgeon S, Laroche G

Partial Least-Squares Regression as a Tool To Predict Fluoropolymer Surface Modification by Dielectric Barrier Discharge in a Corona Process Configuration in a Nitrogen-Organic Gaseous Precursor Environment

Journal Article

Ind Eng Chem Res, 57 (22), pp. 7476-7485, 2018, ISSN: 0888-5885.

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Laurent M, Desjardins E, Meichelboeck M, Belinger A, Naudé N, Stafford L, Gherardi N, Laroche G

Influence of a square pulse voltage on argon-ethyl lactate discharges and their plasma-deposited coatings using time-resolved spectroscopy and surface characterization

Journal Article

Phys Plasmas, 25 (10), pp. 103504, 2018, ISSN: 1070-664X.

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Astruc J, Nagalakshmaiah M, Laroche G, Grandbois M, Elkoun S, Robert M

Isolation of cellulose-II nanospheres from flax stems and their physical and morphological properties.

Journal Article

Carbohydr Polym, 178 , pp. 352-359, 2017, ISSN: 0144-8617.

Abstract | Links:

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Active projects

  • Centre de recherche sur les matériaux avancés, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2020-04-30
  • Centres hospitaliers universitaires de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Characterization of an industrial plasma process to treat fluoropolymers and polyethylene terephthalate for the solar energy industry, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2018-01-01 to 2022-12-31
  • Development of an intraosseous transcutaneous orthopaedic implant (ITAP) resistant to bacteria infections through the combination of passive and active strategies, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2016-08-01 to 2021-07-31
  • Endothelial progenitor cell adhesion to biomimetic vascular substitutes, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Concours transitoire de subvention de fonctionnement : 2014-2015, from 2015-07-01 to 2020-06-30
  • Fusion /Centre Québécois sur les Matériaux Fonctionnels (CQMF/QCAM), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2023-03-31
  • Modification and characterisation or surfaces and plasma processes for biotechnological applications, Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2021-03-31
  • Replacement of lead-silver anodes with Ti-based anodes in zinc electrowinning process: (feasibility, coating developement, side effects, performance and energy efficiency), Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2019-01-01 to 2023-03-31

Recently finished projects

  • Development of a new high efficiency method for drug delivery using nanoparticles and liquid precursor in ..., Subvention, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-01-03 to 2019-07-02
Data provided by the Université Laval research projects registery