Gaétan Laroche is a professor at the Department of Materials Engineering of the Faculty of Science and Engineering at Laval University. He is a member of the Centre de Recherche sur les Matériaux Avancés (CERMA) at Laval University and of Quebec Center on Advanced Materials (QCAM). His research focuses on the surface modification of biomedical materials to improve their biocompatibility. Dr. Laroche is internationally renowned for his work on surface modification of materials that make use of the use of gaseous plasmas. More specifically, he is developing surface modification strategies for vascular and orthopedic biomaterials to improve their biocompatibility. Dr. Laroche was awarded the title of Fellow of Biomaterials Science and Engineering (FBSE) from the International Union of Societies of Biomaterials Science and Engineering. Engaged both academically and scientifically, Dr. Laroche sat on several scientific research evaluation committees and was a member of the executive committee responsible for organizing the prestigious World Biomaterials Congress held in Montreal in May 2016. He was also awarded the joint prize given by the Club des Ambassadeurs of the Palais des congrès de Montréal and the Fonds de recherche du Québec and was chosen as the personality of the week by Le Soleil / Radio-Canada.

Towards materials with better blood compatibility
Today, cardiovascular disease is one of the leading causes of death in the world, killing 17 million people a year. For about 1.5 million patients, the best solution is to use a vascular substitute to replace obstructed blood vessels. In this context, Dr. Laroche’s team seeks to develop surface modification strategies for synthetic materials to allow better integration with the physiological medium.

Fighting against infection of orthopedic prostheses infection
Infection is one of the main problems when implanting orthopedic prostheses. The modification of the chemical composition of orthopedic materials makes it possible to improve their interactions with cells of the human body and to actively combat any bacterial colonization.

Hôpital Saint-François d'Assise
10, rue de l'Espinay
Québec, Québec
Canada G1L 3L5
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François S, Chakfé N, Durand B, Laroche G

Effect of polyester prothesis micro-texture on endothelial cell adhesion and proliferation

Journal Article

Trends Biomater Artif Organs, 22 , pp. 89-99, 2008, ISSN: 0971-1198.

Touzin M, Chevallier P, Lewis F, Turgeon S, Holvoet S, Laroche G, Mantovani D

Study on the stability of plasma-polymerized fluorocarbon ultra-thin coatings on stainless steel in water

Journal Article

Surf Coat Tech, 23 , pp. 4884-4891, 2008, ISSN: 0257-8972.

Vallieres K, Chevallier P, Sarra-Bournet C, Turgeon S, Laroche G

AFM imaging of immobilized fibronectin: does the surface conjugation scheme affect the protein orientation/conformation?

Journal Article

Langmuir, 23 (19), pp. 9745-51, 2007, ISSN: 0743-7463.

Abstract | Links:

Vallieres K, Petitclerc E, Laroche G

Covalent grafting of fibronectin onto plasma-treated PTFE: influence of the conjugation strategy on fibronectin biological activity.

Journal Article

Macromol Biosci, 7 (5), pp. 738-45, 2007, ISSN: 1616-5187.

Abstract | Links:

Gagné L, Laroche G

Engineering biomaterials surfaces using micropatterning

Journal Article

Adv Mater Res, 15-17 (THERMEC 2006 Supplement), pp. 77-82, 2007, ISSN: 1435-1889.

François S, Vallières K, Laroche G

Does the Luminal Surface of a Biomaterial Modifies its Healing Characteristics and Endothelialization

Book Chapter

N, Chakfé; B, Durand; JG, Kretz (Ed.): New Technologies in Vascular Biomaterials-Fundamental about Stents II, pp. 71-92, Strasbourg, Europrot, 2007, ISBN: 2952395918.

Gagne L, Rivera G, Laroche G

Micropatterning with aerosols: application for biomaterials.

Journal Article

Biomaterials, 27 (31), pp. 5430-9, 2006, ISSN: 0142-9612.

Abstract | Links:

Haidopoulos M, Turgeon S, Sarra-Bournet C, Laroche G, Mantovani D

Development of an optimized electrochemical process for subsequent coating of 316 stainless steel for stent applications.

Journal Article

J Mater Sci Mater Med, 17 (7), pp. 647-57, 2006, ISSN: 0957-4530.

Abstract | Links:

Sarra-Bournet C, Turgeon S, Mantovani D, Laroche G

Comparison of atmospheric-pressure plasma versus low-pressure RF plasma for surface functionalization of PTFE for biomedical applications

Journal Article

Plasma Process Polym, 3 (6-7), pp. 506-515, 2006, ISSN: 1612-8850.

Sarra-Bournet C, Turgeon S, Mantovani D, Laroche G

A study of atmospheric pressure plasma discharges for surface functionalization of PTFE used in biomedical applications

Journal Article

J Phys D Appl Phys, 39 (16), pp. 3461-3469, 2006, ISSN: 0022-3727.

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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur les matériaux avancés, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2020-04-30
  • Centre Québécois sur les Matériaux Fonctionnels (CQMF), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2023-03-31
  • Characterization of an industrial plasma process to treat fluoropolymers and polyethylene terephthalate for the solar energy industry, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2018-01-01 to 2022-12-31
  • Development of an intraosseous transcutaneous orthopaedic implant (ITAP) resistant to bacteria infections through the combination of passive and active strategies, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2016-08-01 to 2021-07-31
  • Endothelial progenitor cell adhesion to biomimetic vascular substitutes, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Concours transitoire de subvention de fonctionnement : 2014-2015, from 2015-07-01 to 2020-06-30
  • Modification and characterisation or surfaces and plasma processes for biotechnological applications, Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2021-03-31
  • Replacement of lead-silver anodes with Ti-based anodes in zinc electrowinning process: (feasibility, coating developement, side effects, performance and energy efficiency), Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2019-01-01 to 2023-03-31

Recently finished projects

  • Development of a new high efficiency method for drug delivery using nanoparticles and liquid precursor in ..., Subvention, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-01-03 to 2019-07-02
  • Subvention pour création d'une bourse pour étudiant., Subvention, Fondation du CHU de Québec, from 2018-05-01 to 2019-04-26
  • Subvention pour la création d'une bourse, Subvention, Fondation du CHU de Québec, from 2018-04-09 to 2019-03-31
Data provided by the Université Laval research projects registery