Gaétan Laroche is a professor at the Department of Materials Engineering of the Faculty of Science and Engineering at Laval University. He is a member of the Centre de Recherche sur les Matériaux Avancés (CERMA) at Laval University and of Quebec Center on Advanced Materials (QCAM). His research focuses on the surface modification of biomedical materials to improve their biocompatibility. Dr. Laroche is internationally renowned for his work on surface modification of materials that make use of the use of gaseous plasmas. More specifically, he is developing surface modification strategies for vascular and orthopedic biomaterials to improve their biocompatibility. Dr. Laroche was awarded the title of Fellow of Biomaterials Science and Engineering (FBSE) from the International Union of Societies of Biomaterials Science and Engineering. Engaged both academically and scientifically, Dr. Laroche sat on several scientific research evaluation committees and was a member of the executive committee responsible for organizing the prestigious World Biomaterials Congress held in Montreal in May 2016. He was also awarded the joint prize given by the Club des Ambassadeurs of the Palais des congrès de Montréal and the Fonds de recherche du Québec and was chosen as the personality of the week by Le Soleil / Radio-Canada.

Towards materials with better blood compatibility
Today, cardiovascular disease is one of the leading causes of death in the world, killing 17 million people a year. For about 1.5 million patients, the best solution is to use a vascular substitute to replace obstructed blood vessels. In this context, Dr. Laroche’s team seeks to develop surface modification strategies for synthetic materials to allow better integration with the physiological medium.

Fighting against infection of orthopedic prostheses infection
Infection is one of the main problems when implanting orthopedic prostheses. The modification of the chemical composition of orthopedic materials makes it possible to improve their interactions with cells of the human body and to actively combat any bacterial colonization.

Hôpital Saint-François d'Assise
10, rue de l'Espinay
E0-175
Québec, Québec
Canada G1L 3L5
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Bashth OS, Elkhodiry MA, Laroche G, Hoesli CA

Surface grafting of Fc-binding peptides as a simple platform to immobilize and identify antibodies that selectively capture circulating endothelial progenitor cells.

Journal Article

Biomater Sci, 2020, ISSN: 2047-4830.

Abstract | Links:

Duran IR, Vanslambrouck S, Chevallier P, Hoesli CA, Laroche G

Atmospheric pressure cold plasma versus wet-chemical surface treatments for carboxyl functionalization of polylactic acid: A first step toward covalent immobilization of bioactive molecules.

Journal Article

Colloids Surf B Biointerfaces, 189 , pp. 110847, 2020, ISSN: 0927-7765.

Abstract | Links:

Royer C, Guay-Begin AA, Chanseau C, Chevallier P, Bordenave L, Laroche G, Durrieu MC

Bioactive micropatterning of biomaterials for induction of endothelial progenitor cell differentiation: Acceleration of in situ endothelialization.

Journal Article

J Biomed Mater Res A, 108 (7), pp. 1479-1492, 2020, ISSN: 1549-3296.

Abstract | Links:

Padiolleau L, Chanseau C, Durrieu S, Ayela C, Laroche G, Durrieu MC

Directing hMSCs fate through geometrical cues and mimetics peptides.

Journal Article

J Biomed Mater Res A, 108 (2), pp. 201-211, 2020, ISSN: 1549-3296.

Abstract | Links:

Vanslambrouck S, Chevallier P, Guay-Begin AA, Laroche G

Effect of linking arm hydrophilic/hydrophobic nature, length and end-group on the conformation and the RGD accessibility of surface-immobilized fibronectin.

Journal Article

Mater Sci Eng C Mater Biol Appl, 107 , pp. 110335, 2020, ISSN: 0928-4931.

Abstract | Links:

Rodríguez Durán I, Durocher-Jean A, Profili J, Stafford L, Laroche G

Atmospheric pressure Townsend discharges as a promising tool for the one-step deposition of antifogging coatings from N2O/TMCTS mixtures

Journal Article

Plasma Process Polym, pp. e1900186 (15 pages), 2020, ISSN: 1612-8850.

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Rodríguez Durán I, Profili J, Stafford L, Laroche G

Beyond microelectronics with 1,3,5,7-tetramethylcyclotetrasiloxane: A promising molecule for anti-fogging coatings

Journal Article

Mater Chem Phys, 242 , pp. 122508 (12 pages), 2020, ISSN: 0254-0584.

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Duran IR, Laroche G

Water drop-surface interactions as the basis for the design of anti-fogging surfaces: Theory, practice, and applications trends.

Journal Article

Adv Colloid Interface Sci, 263 , pp. 68-94, 2019, ISSN: 0001-8686.

Abstract | Links:

Elkhodiry MA, Boulanger MD, Bashth O, Tanguay JF, Laroche G, Hoesli CA

Isolating and expanding endothelial progenitor cells from peripheral blood on peptide-functionalized polystyrene surfaces.

Journal Article

Biotechnol Bioeng, 116 (10), pp. 2598-2609, 2019, ISSN: 0006-3592.

Abstract | Links:

Barrak H, Ahmedi R, Chevallier P, M'nif A, Laroche G, Hamzaoui AH

Highly efficient extraction of rare earth elements and others ions from green phosphoric acid medium using TMSEDTA@GO@Fe3O4 core-shell

Journal Article

Sep Purif Technol, 222 , pp. 145-151, 2019, ISSN: 1383-5866.

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89 entries « 1 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur les matériaux avancés, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2025-04-30
  • Centre Québécois sur les Matériaux Fonctionnels (CQMF), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2023-03-31
  • Characterization of an industrial plasma process to treat fluoropolymers and polyethylene terephthalate for the solar energy industry, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2018-01-01 to 2022-12-31
  • Conjugaison de molécules antivirales à la surface des matériaux: une solution pour limiter la transmission de la COVID-19, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions Alliance du CRSNG relatives à la COVID-19, from 2020-07-01 to 2021-06-30
  • Development of an intraosseous transcutaneous orthopaedic implant (ITAP) resistant to bacteria infections through the combination of passive and active strategies, Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2016-08-01 to 2021-07-31
  • Modification and characterisation or surfaces and plasma processes for biotechnological applications, Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2021-03-31
  • Prothèse orthopédique antibactérienne, Partenariat, Ministère de l'Économie et de l'Innovation, Programme de soutien aux organismes de recherche et d’innovation (PSO) - Volet 1 : Soutien au fonctionnement d'organisme (Ancien PSVT), from 2020-08-03 to 2021-02-28
  • Replacement of lead-silver anodes with Ti-based anodes in zinc electrowinning process: (feasibility, coating developement, side effects, performance and energy efficiency), Partenariat, Conseil de recherches en sciences naturelles et génie Canada, Subventions de recherche et développement coopérative (RDC), from 2019-01-01 to 2023-03-31

Recently finished projects

  • Development of a new high efficiency method for drug delivery using nanoparticles and liquid precursor in ..., Subvention, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-01-03 to 2019-07-02
  • Endothelial progenitor cell adhesion to biomimetic vascular substitutes, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Concours transitoire de subvention de fonctionnement : 2014-2015, from 2015-07-01 to 2020-06-30
Data provided by the Université Laval research projects registery