Dr. Pouliot obtained doctorates in medicine (M.D.) and in Physiology-Endocrinology (Ph.D.) from Laval University. After completing a residency in Urology (F.R.C.S.C.), he did a post-doctoral fellowship in Urologic Oncology and molecular imaging at the University of California, Los Angeles (UCLA). Since 2010, he has practiced as a urologist-oncologist in the Quebec City University Hospital Center. He is also an associate professor in Laval University’s Department of surgery. He oversees the CHU de Québec multidisciplinary clinic in castration-resistant prostate cancer. In 2014, he was the recipient of the Prostate Cancer Canada/Movember Rising Star Award. He is also the recipient of the FRQS Clinical Research Scholars Junior 1 and 2 and Senior. His clinical and preclinical research interests include the detection and characterization of high risk, advanced and metastatic prostate cancers using transcriptional amplification systems or positron emission tomography (PET) with tracers such as fluoro-deoxyglucose or PSMA ligands (PyL, MP-1404).  He is also involved in the development of new radioligand therapeutics.

His research program has four aims: 1) To develop a dynamic imaging method based on a transcriptional amplification system allowing the sensitive detection of a luminescent reporter gene under the control of prostate cancer specific promoters. This microscopy method will allow predicting the patient’s response to antiandrogen treatments. 2) Use positron emission tomography imaging (PET/CT) as a quantitative method to identify the very high risk prostate cancer and to assess metastasis individual response, in addition to global response to systemic treatment. 3) Develop a prostate cancer immunotherapy based on a transcriptional amplification system specific to prostate cancer. This vaccine vector will allow the introduction of recombinant genes in patient’s prostate cancer cells to induce an efficient immune response against cancer cells.  4) Characterize the androgen receptor (AR) activation in castration resistant prostate cancer patients. This project aims to determine which steroids activate the AR under chemical castration and to identify new AR interacting partners using proteomics.

L'Hôtel-Dieu de Québec
6, rue McMahon
0624
Québec, Québec
Canada G1R 2J6
72 entries « 7 of 8 »

Pouliot F, Pantuck A, Imbeault A, Shuch B, Calimlim B, Audet JF, Finley DS, Dujardin T

Multivariate analysis of the factors involved in loss of renal differential function after laparoscopic partial nephrectomy: a role for warm ischemia time.

Journal Article

Can Urol Assoc J, 5 (2), pp. 89-95, 2011, ISSN: 1911-6470.

Abstract | Links:

Shuch B, Crispen PL, Leibovich BC, Larochelle JC, Pouliot F, Pantuck AJ, Liu W, Crepel M, Schuckman A, Rigaud J, Bouchot O, Patard JJ, Skinner D, Belldegrun AS, Blute ML

Cardiopulmonary bypass and renal cell carcinoma with level IV tumour thrombus: can deep hypothermic circulatory arrest limit perioperative mortality?

Journal Article

BJU Int, 107 (5), pp. 724-728, 2011, ISSN: 1464-4096.

Abstract | Links:

Finley DS, Pouliot F, Chin AI, Shuch B, Pantuck AJ, Belldegrun AS, Dekernion JB

Immunological therapy in urological malignancy: novel combination strategies.

Journal Article

Int J Urol, 18 (2), pp. 94-101, 2011, ISSN: 0919-8172.

Abstract | Links:

Pouliot F, Wu L

Cardiac glycosides may affect prostate specific antigen levels.

Journal Article

J Urol, 184 (5), pp. 1831-2, 2010, ISSN: 0022-5347.

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Pouliot F, Shuch B, Larochelle JC, Pantuck A, Belldegrun AS

Contemporary management of renal tumors with venous tumor thrombus.

Journal Article

J Urol, 184 (3), pp. 833-41; quiz 1235, 2010, ISSN: 0022-5347.

Abstract | Links:

Pouliot F, Lebel MH, Audet JF, Dujardin T

Determination of success by objective scintigraphic criteria after laparoscopic pyeloplasty.

Journal Article

J Endourol, 24 (2), pp. 299-304, 2010, ISSN: 0892-7790.

Abstract | Links:

Finley DS, Pouliot F, Miller DC, Belldegrun AS

Primary and salvage cryotherapy for prostate cancer.

Journal Article

Urol Clin North Am, 37 (1), pp. 67-82, Table of Contents, 2010, ISSN: 0094-0143.

Abstract | Links:

Shuch B, Said J, LaRochelle JC, Zhou Y, Li G, Klatte T, Pouliot F, Kabbinavar FF, Belldegrun AS, Pantuck AJ

Histologic evaluation of metastases in renal cell carcinoma with sarcomatoid transformation and its implications for systemic therapy.

Journal Article

Cancer, 116 (3), pp. 616-24, 2010, ISSN: 0008-543X.

Abstract | Links:

Caumartin Y, Pouliot F, Sabbagh R, Dujardin T

Chylous ascites as a complication of laparoscopic donor nephrectomy.

Journal Article

Transpl Int, 18 (12), pp. 1378-81, 2005, ISSN: 0934-0874.

Abstract | Links:

Pouliot F, Labrie C

Expression profile of agonistic Smads in human breast cancer cells: absence of regulation by estrogens.

Journal Article

Int J Cancer, 81 (1), pp. 98-103, 1999, ISSN: 0020-7136.

Abstract | Links:

72 entries « 7 of 8 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
  • Modeling Prostate Cancer in 30 using tissue engineering , Subvention, Association canadienne d'urologie, from 2019-09-11 to 2020-09-10
  • National Program on Radioligand Therapy for Prostate Cancer, Subvention, Cancer de la prostate Canada, from 2018-01-01 to 2022-12-31
  • Optimiser les soins des patients atteints du cancer de la prostate résistant à la castration en utilisant une stratégie de triple traceur en imagerie moléculaire et en radiothérapie ciblée, Subvention, Fonds de recherche du Québec - Santé, ONCOPOLE EMC2: Équipes multi-institutionnelles contre le cancer, from 2018-04-01 to 2021-03-31
  • Surveillance of Complex Renal Cysts: The SOCRATIC study, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-10-01 to 2028-09-30
  • Utilisation de l’imagerie moléculaire par microscopie à bioluminescence ou par tomographie par émission de positrons afin d’optimiser les stratégies thérapeutiques des patients atteints de cancers urologiques, Subvention, Fonds de recherche du Québec - Santé, Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, from 2019-07-01 to 2023-06-30

Recently finished projects

  • Développement et utilisation de systèmes d’amplification transcriptionnelle multigéniques à des fins diagnostiques et thérapeutiques pour améliorer la prise en charge du cancer de la prostate., Subvention, Fonds de recherche du Québec - Santé, Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, from 2017-07-01 to 2019-06-30
  • Support statistique pour la recherche en Urologie-oncologie, Subvention, Fondation du CHU de Québec, from 2019-03-25 to 2020-03-24
Data provided by the Université Laval research projects registery