Dr. Éric Vigneault is a radiation oncologist-clinician in the Department of Radiation Oncology at CHUQ, and a researcher in the oncology axis of the CHU Research Centre of Laval University-Quebec, affiliated with the Centre for Cancer Research at Laval University.
He is also Associate Clinical Professor in the Department of Medicine of the Faculty of Medicine at Laval University. Dr. Vigneault has been actively involved in the development of the first Iodine-125 prostate brachytherapy program in Canada, and is the pioneer of high dose-rate, non-permanent brachytherapy in Canada. He is the principal investigator of randomized phase II CCTG studies, comparing HDR brachytherapy with conventional radiotherapy in the treatment of intermediate-risk prostatic cancers (PR15), and comparing HDR brachytherapy with LDR monotherapy (PR19).
Dr. Vigneault is deeply involved at the national level, including as the former President of the Canadian Association of Radiation Oncologists, as a member of the Steering Committee of the Canadian Urologic Oncology Group (CUOG), as well as internationally as the Associate Editor of the Brachytherapy journal.
Since 2015, he holds the Research Chair in Image-guided Brachytherapy, whose mission is to integrate technological advances in the field of imaging, computer science, dosimetry optimization, radioactive source implantation systems, as well as clinical expertise to improve brachytherapy treatments for solid tumors, thereby promoting a better therapeutic ratio – i.e., an increase in tumor control and a decrease in toxicity. This research Chair is part of Laval University’s Program for the Advancement of Innovation, Research and Teaching, which aims to create a research environment that stimulates innovation, inventiveness and creativity among research professors.
The objectives of the Chair are:
- Improve the integration of real-time imaging, implantation and dosimetry systems to improve the quality and accuracy of radioactive material implantation in cancers.
- Develop protocols for treating tumor sites by brachytherapy.
- Promote clinical research to evaluate and compare tumor controls, toxicities, and quality of life assessment with conventional treatment, including dissemination of results and knowledge transfer;
- Promote the education and training of graduate students and fellows in the field of brachytherapy;
- Develop clinical databases of tissue banks collected to support translational research.
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DNA repair gene polymorphisms, tumor control, and treatment toxicity in prostate cancer patients treated with permanent implant prostate brachytherapy.Journal Article
Prostate, 2020, ISSN: 0270-4137.
Canadian Urological Association-Canadian Urologic Oncology Group guideline on metastatic castration-naive and castration-sensitive prostate cancer.Journal Article
Can Urol Assoc J, 14 (2), pp. 17-23, 2020, ISSN: 1911-6470.
The association of intraprostatic calcifications and dosimetry parameters with biochemical control after permanent prostate implant.Journal Article
Brachytherapy, 18 (6), pp. 787-792, 2019, ISSN: 1538-4721.
2019 Canadian Urological Association (CUA)-Canadian Uro Oncology Group (CUOG) guideline: Management of castration-resistant prostate cancer (CRPC).Journal Article
Can Urol Assoc J, 13 (10), pp. 307-314, 2019, ISSN: 1911-6470.
A Phase 2 Randomized Pilot Study Comparing High-Dose-Rate Brachytherapy and Low-Dose-Rate Brachytherapy as Monotherapy in Localized Prostate Cancer.Journal Article
Adv Radiat Oncol, 4 (4), pp. 631-640, 2019, ISSN: 2452-1094.
National Trends and Dynamic Responses in the Canadian Radiation Oncology Workforce From 1990 to 2018.Journal Article
Int J Radiat Oncol Biol Phys, 105 (1), pp. 31-41, 2019, ISSN: 0360-3016.
MRI-based interstitial brachytherapy for vaginal tumors: A multi-institutional study on practice patterns, contouring, and consensus definitions of target volumes.Journal Article
Brachytherapy, 18 (5), pp. 598-605, 2019, ISSN: 1538-4721.
2019 Canadian Urological Association (CUA)-Canadian Uro Oncology Group (CUOG) guidelines for the management of castration-resistant prostate cancer (CRPC).Journal Article
Can Urol Assoc J, 2019, ISSN: 1911-6470.
A Prospective Phase 2 Trial of Transperineal Ultrasound-Guided Brachytherapy for Locally Recurrent Prostate Cancer After External Beam Radiation Therapy (NRG Oncology/RTOG-0526).Journal Article
Int J Radiat Oncol Biol Phys, 103 (2), pp. 335-343, 2019, ISSN: 0360-3016.
Impact of a dominant intraprostatic lesion (DIL) boost defined by sextant biopsy in permanent I-125 prostate implants on biochemical disease free survival (bDFS) and toxicity outcomes.Journal Article
Radiother Oncol, 133 , pp. 62-67, 2019, ISSN: 0167-8140.
- Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
- Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
- Chaire de recherche sur la curiethérapie guidée par imagerie, Subvention, Fondation de l'Université Laval, Chaires de recherche sans organismes subventionnaires, from 2015-05-01 to 2022-03-31
Recently finished projects
- (FRSQ 78415)Evaluation of sphingolipid cermide and intracellular signaling markers of prostate ... prostate cancer receiving a hypofractionation regimen treatment combined with a high dose rate brachytherapy boost., Subvention, Canadian Urologic Oncology Group, from 2017-08-22 to 2018-08-21
- (FRSQ 84704)Projet de recherche avec étudiant post-doctoral en curiethérapie, Subvention, Fondation du CHU de Québec, from 2017-10-05 to 2018-10-04
- Détresse et satisfactions face au processus informationnel et décisionnel lors d'un cancer de la prostate localisé, Subvention, Fondation de l'Université Laval, from 2017-02-01 to 2020-03-31