Dr. Eric Boilard, PhD, is a recipient of a CIHR award, Associate Professor in the Department of Microbiology and Immunology at the Laval University School of Medicine, and a researcher at the CHU de Québec Research Center. He is also a researcher with the Canadian National Transplant Research Program (CNTRP), where he is co-leader and consulting member of the international group Systemic Lupus Collaborating Clinics (SLICC).

He obtained his PhD in Microbiology and Immunology from Laval University (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard highlighted the role of platelets in rheumatoid arthritis (Boilard et al., Science 2010).

His research aims to better understand the pathogenesis of rheumatic diseases, and to improve the success of blood transplants and transfusions to develop new therapeutics and biomarkers. He investigates how platelets and the small extracellular vesicles they produce, called microparticles, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and the cases of immune responses involved in transplant rejection and adverse reactions related to transfusions. He conducts clinical research with patients and mouse models of disease.

He is an internationally renowned scientist and lecturer recognized by his peers. He won the Radio-Canada Award for the greatest medical discovery of the year (2011 and 2013), the Radio-Canada and Le Soleil Award of the Scientist of the Year (2011), and is the recipient of the André Dupont Award for Quebec’s most prolific young researcher (2017). His work is in part funded by the CIHR Foundation Program (Platelets and their microparticles: versatile players of inflammation) and NSERC.

CHUL
2705, boulevard Laurier
T-1-49
Québec, Québec
Canada G1V 4G2
85 entries « 9 of 9 »

Rouault M, Rash LD, Escoubas P, Boilard E, Bollinger J, Lomonte B, Maurin T, Guillaume C, Canaan S, Deregnaucourt C, Schrevel J, Doglio A, Gutierrez JM, Lazdunski M, Gelb MH, Lambeau G

Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity.

Journal Article

Biochemistry, 45 (18), pp. 5800-16, 2006, ISSN: 0006-2960.

Abstract | Links:

Granata F, Petraroli A, Boilard E, Bezzine S, Bollinger J, Del Vecchio L, Gelb MH, Lambeau G, Marone G, Triggiani M

Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor.

Journal Article

J Immunol, 174 (1), pp. 464-74, 2005, ISSN: 0022-1767.

Abstract | Links:

Boilard E, Bourgoin SG, Bernatchez C, Surette ME

Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2.

Journal Article

Blood, 102 (8), pp. 2901-9, 2003, ISSN: 0006-4971.

Abstract | Links:

Boilard E, Bourgoin SG, Bernatchez C, Poubelle PE, Surette ME

Interaction of low molecular weight group IIA phospholipase A2 with apoptotic human T cells: role of heparan sulfate proteoglycans.

Journal Article

FASEB J, 17 (9), pp. 1068-80, 2003, ISSN: 0892-6638.

Abstract | Links:

Boilard E, Surette ME

Anti-CD3 and concanavalin A-induced human T cell proliferation is associated with an increased rate of arachidonate-phospholipid remodeling. Lack of involvement of group IV and group VI phospholipase A2 in remodeling and increased susceptibility of proliferating T cells to CoA-independent transacyclase inhibitor-induced apoptosis.

Journal Article

J Biol Chem, 276 (20), pp. 17568-75, 2001, ISSN: 0021-9258.

Abstract | Links:

85 entries « 9 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2023-03-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2022-03-31
  • Pathogenic roles of platelets in sepsis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2020-03-31
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Rôle des plaquettes et de leurs microparticules dans l'inflammation, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2019-08-01 to 2023-07-31
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2020-06-30
  • The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, Subvention, Instituts de recherche en santé du Canada, Autre : Recherche sur la transplantation, from 2013-04-01 to 2022-03-31
  • The role of platelets in rheumatoid arthritis- an animated journey in the arthritic joint, Subvention, Instituts de recherche en santé du Canada, Subventions de planification et dissémination – Programme d’appui communautaire des instituts, from 2019-05-01 to 2020-04-30

Recently finished projects

  • Erythrocyte-derived extracellular vesicles: A biomarker of Parkinson's disease progression, Subvention, Weston Brain institute, Rapid Response, from 2017-03-01 to 2018-11-28
  • Études des vésicules extracellulaires de plaquettes contenant des organelles dans un contexte de transfusion, Partenariat, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-03-18 to 2019-08-15
  • Functions of platelets and microparticles in inflammation., Subvention, Instituts de recherche en santé du Canada, Bourse salariale pour nouveau chercheur, from 2014-08-01 to 2019-07-31
  • Propriétés immunomodulatrices de l'activité bactéricide de la phospholipase A2-IIA sécrétée sur le microbiote, Subvention, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-03-18 to 2019-08-14
Data provided by the Université Laval research projects registery