Dr. Eric Boilard, PhD, is a recipient of a CIHR award, Associate Professor in the Department of Microbiology and Immunology at the Laval University School of Medicine, and a researcher at the CHU de Québec Research Center. He is also a researcher with the Canadian National Transplant Research Program (CNTRP), where he is co-leader and consulting member of the international group Systemic Lupus Collaborating Clinics (SLICC).

He obtained his PhD in Microbiology and Immunology from Laval University (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard highlighted the role of platelets in rheumatoid arthritis (Boilard et al., Science 2010).

His research aims to better understand the pathogenesis of rheumatic diseases, and to improve the success of blood transplants and transfusions to develop new therapeutics and biomarkers. He investigates how platelets and the small extracellular vesicles they produce, called microparticles, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and the cases of immune responses involved in transplant rejection and adverse reactions related to transfusions. He conducts clinical research with patients and mouse models of disease.

He is an internationally renowned scientist and lecturer recognized by his peers. He won the Radio-Canada Award for the greatest medical discovery of the year (2011 and 2013), the Radio-Canada and Le Soleil Award of the Scientist of the Year (2011), and is the recipient of the André Dupont Award for Quebec’s most prolific young researcher (2017). His work is in part funded by the CIHR Foundation Program (Platelets and their microparticles: versatile players of inflammation) and NSERC.

CHUL
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Québec, Québec
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83 entries « 2 of 9 »

Becker Y, Marcoux G, Allaeys I, Julien AS, Loignon RC, Benk-Fortin H, Rollet-Labelle E, Rauch J, Fortin PR, Boilard E

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA.

Journal Article

Front Immunol, 10 , pp. 1026, 2019, ISSN: 1664-3224.

Abstract | Links:

Denis HL, Lamontagne-Proulx J, St-Amour I, Mason SL, Weiss A, Chouinard S, Barker RA, Boilard E, Cicchetti F

Platelet-derived extracellular vesicles in Huntington's disease.

Journal Article

J Neurol, 265 (11), pp. 2704-2712, 2018, ISSN: 0340-5354.

Abstract | Links:

Linge P, Fortin PR, Lood C, Bengtsson AA, Boilard E

The non-haemostatic role of platelets in systemic lupus erythematosus.

Journal Article

Nat Rev Rheumatol, 14 (4), pp. 195-213, 2018.

Abstract | Links:

Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

Journal Article

Proc Natl Acad Sci U S A, 115 (7), pp. E1550-E1559, 2018, ISSN: 0027-8424.

Abstract | Links:

Magron A, Laugier J, Provost P, Boilard E

Pathogen reduction technologies: The pros and cons for platelet transfusion.

Journal Article

Platelets, 29 (1), pp. 2-8, 2018, ISSN: 0953-7104.

Abstract | Links:

Rozmus J, Ivison S, Kariminia A, Leung VM, Sung S, Subrt P, Lee SJ, Boilard E, Walker I, Foley R, Lipton J, Gallagher G, Couban S, Schultz KR

Higher levels of free plasma mitochondrial DNA are associated with the onset of chronic GvHD.

Journal Article

Bone Marrow Transplant, 53 (10), pp. 1263-1269, 2018, ISSN: 0268-3369.

Abstract | Links:

Boilard E

Extracellular vesicles and their content in bioactive lipid mediators: more than a sack of microRNA.

Journal Article

J Lipid Res, 59 (11), pp. 2037-2046, 2018, ISSN: 0022-2275.

Abstract | Links:

Robichaud PP, Munganyiki JE, Boilard E, Surette ME

Polyunsaturated fatty acid elongation and desaturation in activated human T-cells: ELOVL5 is the key elongase.

Journal Article

J Lipid Res, 59 (12), pp. 2383-2396, 2018, ISSN: 0022-2275.

Abstract | Links:

Nieuwland R, Falcon-Perez JM, Soekmadji C, Boilard E, Carter D, Buzas EI

Essentials of extracellular vesicles: posters on basic and clinical aspects of extracellular vesicles.

Journal Article

J Extracell Vesicles, 7 (1), pp. 1548234, 2018, ISSN: 2001-3078.

Abstract | Links:

Thery C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borras FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MA, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Gorecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzas EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekstrom K, El Andaloussi S, Elie-Caille C, Erdbrugger U, Falcon-Perez JM, Fatima F, Fish JE, Flores-Bellver M, Forsonits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gamez-Valero A, Gardiner C, Gartner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Gorgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ 2nd, Kornek M, Kosanovic MM, Kovacs AF, Kramer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lasser C, Laurent LC, Lavieu G, Lazaro-Ibanez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Line A, Linnemannstons K, Llorente A, Lombard CA

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Journal Article

J Extracell Vesicles, 7 (1), pp. 1535750, 2018, ISSN: 2001-3078.

Abstract | Links:

83 entries « 2 of 9 »
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Active projects

  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Centre hospitalier universitaire de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2021-03-31
  • Functions of platelets and microparticles in inflammation., Subvention, Instituts de recherche en santé du Canada, Bourse salariale pour nouveau chercheur, from 2014-08-01 to 2019-07-31
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2020-06-30

Recently finished projects

  • Erythrocyte-derived extracellular vesicles: A biomarker of Parkinson's disease progression, Subvention, Weston Brain institute, Rapid Response, from 2017-03-01 to 2018-11-28
  • Release, delivery and cell programming effects of platelet microparticles and microRNAs., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-10-01 to 2018-03-31
  • Role of extracellular mitochondria in adverse transfusion reaction, Partenariat, MITACS Inc., Accélération Québec (MITACS/FQRNT), from 2015-05-21 to 2017-11-30
  • Role of extracellular mitochondria in adverse transfusion reactions- A prospective study. (FONDS 0493), Subvention, Fondation de l'Université Laval, from 2014-11-05 to 2017-10-31
  • The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, Subvention, Instituts de recherche en santé du Canada, Autre : Recherche sur la transplantation, from 2013-04-01 to 2018-03-31
Data provided by the Université Laval research projects registery