Dr. Eric Boilard, PhD, is a recipient of a CIHR award, Associate Professor in the Department of Microbiology and Immunology at the Laval University School of Medicine, and a researcher at the CHU de Québec Research Center. He is also a researcher with the Canadian National Transplant Research Program (CNTRP), where he is co-leader and consulting member of the international group Systemic Lupus Collaborating Clinics (SLICC).

He obtained his PhD in Microbiology and Immunology from Laval University (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard highlighted the role of platelets in rheumatoid arthritis (Boilard et al., Science 2010).

His research aims to better understand the pathogenesis of rheumatic diseases, and to improve the success of blood transplants and transfusions to develop new therapeutics and biomarkers. He investigates how platelets and the small extracellular vesicles they produce, called microparticles, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and the cases of immune responses involved in transplant rejection and adverse reactions related to transfusions. He conducts clinical research with patients and mouse models of disease.

He is an internationally renowned scientist and lecturer recognized by his peers. He won the Radio-Canada Award for the greatest medical discovery of the year (2011 and 2013), the Radio-Canada and Le Soleil Award of the Scientist of the Year (2011), and is the recipient of the André Dupont Award for Quebec’s most prolific young researcher (2017). His work is in part funded by the CIHR Foundation Program (Platelets and their microparticles: versatile players of inflammation) and NSERC.

CHUL
2705, boulevard Laurier
T-1-49
Québec, Québec
Canada G1V 4G2
86 entries « 2 of 9 »

Lamontagne-Proulx J, St-Amour I, Labib R, Pilon J, Denis HL, Cloutier N, Roux-Dalvai F, Vincent AT, Mason SL, Duchez AC, Droit A, Lacroix S, Dupre N, Langlois M, Chouinard S, Panisset M, Barker RA, Boilard E, Cicchetti F

Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.

Journal Article

Neurobiol Dis, 124 , pp. 163-175, 2019, ISSN: 0969-9961.

Abstract | Links:

Denis HL, Lamontagne-Proulx J, St-Amour I, Mason SL, Rowley JW, Cloutier N, Tremblay ME, Vincent AT, Gould PV, Chouinard S, Weyrich AS, Rondina MT, Barker RA, Boilard E, Cicchetti F

Platelet abnormalities in Huntington's disease.

Journal Article

J Neurol Neurosurg Psychiatry, 90 (3), pp. 272-283, 2019, ISSN: 0022-3050.

Abstract | Links:

Becker Y, Marcoux G, Allaeys I, Julien AS, Loignon RC, Benk-Fortin H, Rollet-Labelle E, Rauch J, Fortin PR, Boilard E

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA.

Journal Article

Front Immunol, 10 , pp. 1026, 2019, ISSN: 1664-3224.

Abstract | Links:

Duchez AC, Boudreau LH, Naika GS, Rousseau M, Cloutier N, Levesque T, Gelb MH, Boilard E

Respective contribution of cytosolic phospholipase A2α and secreted phospholipase A2 IIA to inflammation and eicosanoid production in arthritis.

Journal Article

Prostaglandins Other Lipid Mediat, 143 , pp. 106340, 2019, ISSN: 1098-8823.

Abstract | Links:

Clayton A, Boilard E, Buzas EI, Cheng L, Falcon-Perez JM, Gardiner C, Gustafson D, Gualerzi A, Hendrix A, Hoffman A, Jones J, Lasser C, Lawson C, Lenassi M, Nazarenko I, O'Driscoll L, Pink R, Siljander PR, Soekmadji C, Wauben M, Welsh JA, Witwer K, Zheng L, Nieuwland R

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles.

Journal Article

J Extracell Vesicles, 8 (1), pp. 1647027, 2019, ISSN: 2001-3078.

Abstract | Links:

Denis HL, Lamontagne-Proulx J, St-Amour I, Mason SL, Weiss A, Chouinard S, Barker RA, Boilard E, Cicchetti F

Platelet-derived extracellular vesicles in Huntington's disease.

Journal Article

J Neurol, 265 (11), pp. 2704-2712, 2018, ISSN: 0340-5354.

Abstract | Links:

Linge P, Fortin PR, Lood C, Bengtsson AA, Boilard E

The non-haemostatic role of platelets in systemic lupus erythematosus.

Journal Article

Nat Rev Rheumatol, 14 (4), pp. 195-213, 2018.

Abstract | Links:

Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

Journal Article

Proc Natl Acad Sci U S A, 115 (7), pp. E1550-E1559, 2018, ISSN: 0027-8424.

Abstract | Links:

Magron A, Laugier J, Provost P, Boilard E

Pathogen reduction technologies: The pros and cons for platelet transfusion.

Journal Article

Platelets, 29 (1), pp. 2-8, 2018, ISSN: 0953-7104.

Abstract | Links:

Rozmus J, Ivison S, Kariminia A, Leung VM, Sung S, Subrt P, Lee SJ, Boilard E, Walker I, Foley R, Lipton J, Gallagher G, Couban S, Schultz KR

Higher levels of free plasma mitochondrial DNA are associated with the onset of chronic GvHD.

Journal Article

Bone Marrow Transplant, 53 (10), pp. 1263-1269, 2018, ISSN: 0268-3369.

Abstract | Links:

86 entries « 2 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2023-03-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2022-03-31
  • Pathogenic roles of platelets in sepsis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2020-03-31
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Rôle des plaquettes et de leurs microparticules dans l'inflammation, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2019-08-01 to 2023-07-31
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2020-06-30
  • The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, Subvention, Instituts de recherche en santé du Canada, Autre : Recherche sur la transplantation, from 2013-04-01 to 2022-03-31
  • The role of platelets in rheumatoid arthritis- an animated journey in the arthritic joint, Subvention, Instituts de recherche en santé du Canada, Subventions de planification et dissémination – Programme d’appui communautaire des instituts, from 2019-05-01 to 2020-04-30

Recently finished projects

  • Erythrocyte-derived extracellular vesicles: A biomarker of Parkinson's disease progression, Subvention, Weston Brain institute, Rapid Response, from 2017-03-01 to 2018-11-28
  • Études des vésicules extracellulaires de plaquettes contenant des organelles dans un contexte de transfusion, Partenariat, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-03-18 to 2019-08-15
  • Functions of platelets and microparticles in inflammation., Subvention, Instituts de recherche en santé du Canada, Bourse salariale pour nouveau chercheur, from 2014-08-01 to 2019-07-31
  • Propriétés immunomodulatrices de l'activité bactéricide de la phospholipase A2-IIA sécrétée sur le microbiote, Subvention, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-03-18 to 2019-08-14
Data provided by the Université Laval research projects registery