Dr. Eric Boilard, PhD, is a recipient of a CIHR award, Associate Professor in the Department of Microbiology and Immunology at the Laval University School of Medicine, and a researcher at the CHU de Québec Research Center. He is also a researcher with the Canadian National Transplant Research Program (CNTRP), where he is co-leader and consulting member of the international group Systemic Lupus Collaborating Clinics (SLICC).

He obtained his PhD in Microbiology and Immunology from Laval University (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard highlighted the role of platelets in rheumatoid arthritis (Boilard et al., Science 2010).

His research aims to better understand the pathogenesis of rheumatic diseases, and to improve the success of blood transplants and transfusions to develop new therapeutics and biomarkers. He investigates how platelets and the small extracellular vesicles they produce, called microparticles, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and the cases of immune responses involved in transplant rejection and adverse reactions related to transfusions. He conducts clinical research with patients and mouse models of disease.

He is an internationally renowned scientist and lecturer recognized by his peers. He won the Radio-Canada Award for the greatest medical discovery of the year (2011 and 2013), the Radio-Canada and Le Soleil Award of the Scientist of the Year (2011), and is the recipient of the André Dupont Award for Quebec’s most prolific young researcher (2017). His work is in part funded by the CIHR Foundation Program (Platelets and their microparticles: versatile players of inflammation) and NSERC.

CHUL
2705, boulevard Laurier
T-1-49
Québec, Québec
Canada G1V 4G2
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Huot S, Laflamme C, Fortin PR, Boilard E, Pouliot M

IgG-aggregates rapidly upregulate FcgRI expression at the surface of human neutrophils in a FcgRII-dependent fashion: A crucial role for FcgRI in the generation of reactive oxygen species.

Journal Article

FASEB J, 2020, ISSN: 0892-6638.

Abstract | Links:

Zaid Y, Puhm F, Allaeys I, Naya A, Oudghiri M, Khalki L, Limami Y, Zaid N, Sadki K, Ben El Haj R, Mahir W, Belayachi L, Belefquih B, Benouda A, Cheikh A, Langlois MA, Cherrah Y, Flamand L, Guessous F, Boilard E

Platelets Can Associate with SARS-Cov-2 RNA and Are Hyperactivated in COVID-19.

Journal Article

Circ Res, 2020, ISSN: 0009-7330.

Abstract | Links:

Mailhot B, Christin M, Tessandier N, Sotoudeh C, Bretheau F, Turmel R, Pellerin E, Wang F, Bories C, Joly-Beauparlant C, De Koninck Y, Droit A, Cicchetti F, Scherrer G, Boilard E, Sharif-Naeini R, Lacroix S

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases.

Journal Article

J Exp Med, 217 (9), 2020, ISSN: 0022-1007.

Abstract | Links:

Becker YL, Julien AS, Godbout A, Boilard E, Fortin PR

Pilot study of anti-mitochondrial antibodies in antiphospholipid syndrome.

Journal Article

Lupus, pp. 961203320944481, 2020, ISSN: 0961-2033.

Abstract | Links:

Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell RA, Rowley JW, Salem D, Zufferey A, Laroche A, Levesque T, Patey N, Rauch J, Lood C, Droit A, McKenzie SE, Machlus KR, Rondina MT, Lacroix S, Fortin P, Boilard E

FcγRIIA expression aggravates nephritis and increases platelet activation in systemic lupus erythematosus in mice.

Journal Article

Blood, 2020, ISSN: 0006-4971.

Abstract | Links:

French SL, Butov KR, Allaeys I, Canas J, Morad G, Davenport P, Laroche A, Trubina NM, Italiano JE, Moses MA, Sola-Visner M, Boilard E, Panteleev MA, Machlus KR

Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation.

Journal Article

Blood Adv, 4 (13), pp. 3011-3023, 2020, ISSN: 2473-9529.

Abstract | Links:

Marcoux G, Laroche A, Espinoza Romero J, Boilard E

Role of platelets and megakaryocytes in adaptive immunity.

Journal Article

Platelets, pp. 1-12, 2020, ISSN: 0953-7104.

Abstract | Links:

Dieude M, Turgeon J, Karakeussian Rimbaud A, Beillevaire D, Qi S, Patey N, Gaboury LA, Boilard E, Hebert MJ

Extracellular vesicles derived from injured vascular tissue promote the formation of tertiary lymphoid structures in vascular allografts.

Journal Article

Am J Transplant, 20 (3), pp. 726-738, 2020, ISSN: 1600-6135.

Abstract | Links:

Tessandier N, Melki I, Cloutier N, Allaeys I, Miszta A, Tan S, Milasan A, Michel S, Benmoussa A, Levesque T, Cote F, McKenzie SE, Gilbert C, Provost P, Brisson AR, Wolberg AS, Fortin PR, Martel C, Boilard E

Platelets Disseminate Extracellular Vesicles in Lymph in Rheumatoid Arthritis.

Journal Article

Arterioscler Thromb Vasc Biol, 40 (4), pp. 929-942, 2020, ISSN: 1079-5642.

Abstract | Links:

Kollmann D, Linares-Cervantes I, Ganesh S, Rosales R, Hamar M, Goto T, Urbanellis P, Tessandier N, Boilard E, Bruguera C, Wiebe A, Bartczak A, Yip P, Adeyi O, Selzner M, Selzner N

Normothermic Ex Vivo Liver Perfusion Prevents Intrahepatic Platelet Sequestration After Liver Transplantation.

Journal Article

Transplantation, 104 (6), pp. 1177-1186, 2020, ISSN: 0041-1337.

Abstract | Links:

95 entries « 1 of 10 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., Subvention, Conseil de recherches en sciences naturelles et génie Canada, Subventions à la découverte SD (individuelles et d'équipe), from 2016-04-01 to 2023-03-31
  • COVID-19 trilogy: ARDS, inflammation and coagulopathy, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Possibilité de financement pour une intervention de recherche rapide contre la COVID-19, from 2020-06-01 to 2021-05-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2022-03-31
  • Pathogenic roles of platelets in sepsis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2020-03-01 to 2021-02-28
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2020-04-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, Subvention, La société d'arthrite, from 2020-01-01 to 2022-12-31
  • Rôle des plaquettes et de leurs microparticules dans l'inflammation, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2019-08-01 to 2023-07-31
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2015-07-01 to 2021-06-30
  • The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, Subvention, Instituts de recherche en santé du Canada, Autre : Recherche sur la transplantation, from 2013-04-01 to 2022-03-31
  • The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, Subvention, La société d'arthrite, from 2020-04-01 to 2023-03-31
  • Understanding the pathogenesis of COVID-19, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement : Possibilité de financement canadienne pour une intervention de recherche rapide contre la maladie à coronavirus 2019 (COVID-19), from 2020-03-01 to 2021-02-28

Recently finished projects

  • Centre de recherche en arthrite de l'Université Laval, Subvention, Institutionnel - BDR, BDR - Entités de recherche en émergence, from 2019-01-01 to 2020-01-31
  • Études des vésicules extracellulaires de plaquettes contenant des organelles dans un contexte de transfusion, Partenariat, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-03-18 to 2019-08-15
  • Functions of platelets and microparticles in inflammation., Subvention, Instituts de recherche en santé du Canada, Bourse salariale pour nouveau chercheur, from 2014-08-01 to 2019-07-31
  • Pathogenic roles of platelets in sepsis, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2019-04-01 to 2020-03-31
  • Platelets and their microparticles: versatile players of inflammation., Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2015-07-01 to 2020-06-30
  • Propriétés immunomodulatrices de l'activité bactéricide de la phospholipase A2-IIA sécrétée sur le microbiote, Subvention, MITACS Inc., Bourse de recherche Mitacs Globalink, from 2019-03-18 to 2019-08-14
  • The role of platelets in rheumatoid arthritis- an animated journey in the arthritic joint, Subvention, Instituts de recherche en santé du Canada, Subventions de planification et dissémination – Programme d’appui communautaire des instituts, from 2019-05-01 to 2020-04-30
Data provided by the Université Laval research projects registery