Dr. Eric Boilard, PhD, is a recipient of a CIHR award, Associate Professor in the Department of Microbiology and Immunology at the Laval University School of Medicine, and a researcher at the CHU de Québec Research Center. He is also a researcher with the Canadian National Transplant Research Program (CNTRP), where he is co-leader and consulting member of the international group Systemic Lupus Collaborating Clinics (SLICC).

He obtained his PhD in Microbiology and Immunology from Laval University (2003) and pursued postdoctoral trainings at the Université de Nice-Sophia-Antipolis (2003-2006) and at Harvard University at Brigham and Women’s Hospital (2006-2010). It was during his studies at Harvard that Dr. Boilard highlighted the role of platelets in rheumatoid arthritis (Boilard et al., Science 2010).

His research aims to better understand the pathogenesis of rheumatic diseases, and to improve the success of blood transplants and transfusions to develop new therapeutics and biomarkers. He investigates how platelets and the small extracellular vesicles they produce, called microparticles, contribute to the inflammatory responses in place in rheumatoid arthritis, lupus, and the cases of immune responses involved in transplant rejection and adverse reactions related to transfusions. He conducts clinical research with patients and mouse models of disease.

He is an internationally renowned scientist and lecturer recognized by his peers. He won the Radio-Canada Award for the greatest medical discovery of the year (2011 and 2013), the Radio-Canada and Le Soleil Award of the Scientist of the Year (2011), and is the recipient of the André Dupont Award for Quebec’s most prolific young researcher (2017). His work is in part funded by the CIHR Foundation Program (Platelets and their microparticles: versatile players of inflammation) and NSERC.

CHUL
2705, boulevard Laurier
T1-49
Québec, Québec
Canada G1V 4G2
106 entries « 1 of 11 »

Puhm F, Flamand L, Boilard E

Platelet extracellular vesicles in COVID-19: Potential markers and makers.

Journal Article

J Leukoc Biol, 2021.

Abstract | Links:

Mazilescu LI, Urbanellis P, Kaths MJ, Ganesh S, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli DJ, Turgeon J, Karakeusian Rimbaud A, Hébert MJ, Dieudé M, Alleys I, Dore E, Boilard E, Overkleeft HS, Willems LI, Robinson LA, Selzner M

Prolonged Normothermic Ex Vivo Kidney Perfusion Is Superior to Cold Nonoxygenated and Oxygenated Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts.

Journal Article

Transplant Direct, 7 (10), 2021.

Abstract | Links:

Hasse S, Duchez AC, Fortin P, Boilard E, Bourgoin SG

Interplay between LPA2 and LPA3 in LPA-mediated phosphatidylserine cell surface exposure and extracellular vesicles release by erythrocytes.

Journal Article

Biochem Pharmacol, 192 , 2021.

Abstract | Links:

Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hebert MJ, Pirenne F, Overkleeft H, Florea B, Dieude M, Vingert B, Boilard E

Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules.

Journal Article

Blood, 2021.

Abstract | Links:

Zaid Y, Guessous F, Puhm F, Elhamdani W, Chentoufi L, Morris AC, Cheikh A, Jalali F, Boilard E, Flamand L

Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19.

Journal Article

Blood Adv, 5 (3), 2021.

| Links:

Melki I, Allaeys I, Tessandier N, Levesque T, Cloutier N, Laroche A, Vernoux N, Becker Y, Benk-Fortin H, Zufferey A, Rollet-Labelle E, Pouliot M, Poirier G, Patey N, Belleannee C, Soulet D, McKenzie SE, Brisson A, Tremblay ME, Lood C, Fortin PR, Boilard E

Platelets release mitochondrial antigens in systemic lupus erythematosus.

Journal Article

Sci Transl Med, 13 (581), 2021.

Abstract | Links:

Campbell RA, Boilard E, Rondina MT

Is there a role for the ACE2 receptor in SARS-CoV-2 interactions with platelets?

Journal Article

J Thromb Haemost, 19 (1), 2021.

Abstract | Links:

Marcoux G, Laroche A, Espinoza Romero J, Boilard E

Role of platelets and megakaryocytes in adaptive immunity.

Journal Article

Platelets, 32 (3), 2021.

Abstract | Links:

Puhm F, Boilard E, Machlus KR

Platelet Extracellular Vesicles: Beyond the Blood.

Journal Article

Arterioscler Thromb Vasc Biol, 41 (1), 2021.

Abstract | Links:

Zaid Y, Dore E, Dubuc I, Archambault AS, Flamand O, Laviolette M, Flamand N, Boilard E, Flamand L

Chemokines and eicosanoids fuel the hyperinflammation within the lungs of patients with severe COVID-19.

Journal Article

J Allergy Clin Immunol, 148 (2), 2021.

Abstract | Links:

106 entries « 1 of 11 »
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Active projects

  • Centre de recherche en arthrite (ARThrite), from 2020-11-03 to 2026-04-30
  • Computer-Aided Sperm Analysis (CASA) of sperm motility and hyperactivation, from 2021-04-01 to 2022-03-31
  • Contribution of phospholipase A2 enzymes in the homeostasis of the immune system., from 2016-04-01 to 2023-03-31
  • Mapping anti-mitochondrial antibodies in systemic lupus erythematosus, from 2019-04-01 to 2022-03-31
  • Pathogenesis and immune escape potential of SARS-CoV-2 variants of concern, from 2021-06-01 to 2022-05-31
  • Pathogenic roles of platelets in sepsis, from 2020-03-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-04-01 to 2025-03-31
  • Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis, from 2020-01-01 to 2022-12-31
  • Rôle des plaquettes et de leurs microparticules dans l'inflammation, from 2019-08-01 to 2023-07-31
  • Role of antibodies in platelet response to SARS-CoV-2 and its variants, from 2021-06-01 to 2022-05-31
  • Role of platelets and their mother cell, the megakaryocyte, in COVID-19, from 2021-03-01 to 2022-02-28
  • The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes, from 2013-04-01 to 2022-03-31
  • The impact of antimalarial drugs in arthritis patients exposed to SARS-CoV-2- the CoVIRAL project, from 2020-04-01 to 2023-03-31

Recently finished projects

  • Centre de recherche en arthrite de l'Université Laval, from 2019-01-01 to 2020-01-31
  • COVID-19 trilogy: ARDS, inflammation and coagulopathy, from 2020-06-01 to 2021-05-31
  • Pathogenic roles of platelets in sepsis, from 2019-04-01 to 2020-03-31
  • Platelets and their microparticles: versatile players of inflammation., from 2015-07-01 to 2020-06-30
  • Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis., from 2015-07-01 to 2021-06-30
  • The role of platelets in rheumatoid arthritis- an animated journey in the arthritic joint, from 2019-05-01 to 2020-04-30
  • Understanding the pathogenesis of COVID-19, from 2020-03-01 to 2021-02-28
Data provided by the Université Laval research projects registery