Dr. Dimcho Bachvarov received his B.Sc. and M.Sc. degrees from the University of Sofia in 1975-1978. He obtained his Ph.D. degree in 1986 from the Institute of Molecular Biology at the Bulgarian Academy of Science. In 1994, he was appointed as Adjunct Professor at Laval University’s department of Pharmacology. Consecutively, Dr. Bachvarov was promoted to Assistant Professor (1997), Associate Professor (2002), and since 2005 he has been a Full Professor at Laval University’s Department of Molecular Medicine. During his academic career, Dr. Bachvarov has received different Scholarship Awards, with the most representative being the Ernest J.B. Tomlinson Scholarship Award from the Kidney Foundation of Canada and other Scholarship Awards (Junior and Senior) from Fonds de recherche du Québec – Santé (FRQ-S).

His research interests are focused on studying the initiation and progression mechanisms of epithelial ovarian cancer (EOC) and improving treatment for this deadly disease, including the identification of early diagnostic or prognostic EOC markers. Dr. Bachvarov has published over 80 papers, predominantly in the EOC research field, and has received funding from CIHR, NSERC, CFI, FRQ-S, CRS and the Terry-Fox Research Institute (TFRI). He has been a co-founder and an active member of the provincial Réseau de Recherche en Cancer (RRCancer, established in 2000; see http://www.rrcancer.ca/), and since then, he has been a co-Chair of the Research Committee of the RRCancer axis entitled “Research and Solid State Tumour Biobank”. Following the establishment of RRCancer, Dr. Bachvarov was also in charge of the organization for the RRCancer-supported ovarian tumor bank in the Centre de recherche sur le cancer de l’Université Laval and the Hôtel-Dieu de Québec Hospital (the bank currently contains EOC specimens from about 3,000 patients). He is also the Head of the RRCancer Core Genomic Facility in Québec city. This facility is based on the Agilent dual channel detection microarray platform and has all the necessary equipment, complementary software and expertise required to perform different microarray experiments, including global gene expression and microRNA expression analyses, methylation DNA microarray-based analyses, array-CGH/CNV and Chip-on-CHIP analyses. The Core Genomic Facility in Québec city is providing a genomics and bioinformatics service to Canadian and foreign scientists who implement genomics approaches in their research (see: https://www.crc.ulaval.ca/la-recherche/plateformes/).

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90 entries « 9 of 9 »

Labrie F, Sugimoto Y, Luu-The V, Simard J, Lachance Y, Bachvarov D, Leblanc G, Durocher F, Paquet N

Structure of human type II 5 alpha-reductase gene.

Journal Article

Endocrinology, 131 (3), pp. 1571-3, 1992, ISSN: 0013-7227.

Abstract | Links:

Bachvarov D, Normandeau M, Moss T

Heterogeneity in the Xenopus ribosomal transcription factor xUBF has a molecular basis distinct from that in mammals.

Journal Article

FEBS Lett, 288 (1-2), pp. 55-9, 1991, ISSN: 0014-5793.

Abstract | Links:

Bachvarov D, Moss T

The RNA polymerase I transcription factor xUBF contains 5 tandemly repeated HMG homology boxes.

Journal Article

Nucleic Acids Res, 19 (9), pp. 2331-5, 1991, ISSN: 0305-1048.

Abstract | Links:

Mincheva A, Shindarov L, Karageosov I, Slavchev B, Bachvarov D, Vasilev N, Makaveeva V

Detection of human papillomavirus DNA in gynaecological swabs by filter in situ hybridization.

Journal Article

Acta Virol, 35 (3), pp. 209-17, 1991, ISSN: 0001-723X.

Abstract | Links:

Bachvarov D, Jay E, Ivanov I

Construction of a Co1E1 plasmid bearing inducible high-copy-number phenotype.

Journal Article

Folia Microbiol (Praha), 35 (3), pp. 177-82, 1990, ISSN: 0015-5632.

Abstract | Links:

Ivanov I, Markova N, Bachvarov D, Alexciev K, Saraffova A, Maximova V, Tsaneva I, Markov G

Constitutive expression of a native human interferon-alpha 1 gene in Escherichia coli.

Journal Article

Int J Biochem, 21 (9), pp. 983-5, 1989, ISSN: 0020-711X.

Abstract | Links:

Ivanov IG, Bachvarov DR

Determination of plasmid copy number by the "boiling" method.

Journal Article

Anal Biochem, 165 (1), pp. 137-41, 1987, ISSN: 0003-2697.

Abstract | Links:

Bachvarov DR, Markov GG, Ivanov IG

Sequence heterogeneity of the human alphoid satellite DNA and thermal stability of mismatched alphoid DNA duplexes.

Journal Article

Int J Biochem, 19 (10), pp. 963-71, 1987, ISSN: 0020-711X.

Abstract | Links:

Bachvarov DR, Ivanov IG, Markov GG

Does the concentration of DNA (Co) and the time of incubation (t) as parameters of Cot influence the thermal stability of the DNA duplexes?

Journal Article

Mol Biol Rep, 9 (4), pp. 223-6, 1984, ISSN: 0301-4851.

Abstract | Links:

Bachvarov DR, Ivanov IG

Large scale purification of plasmid DNA.

Journal Article

Prep Biochem, 13 (2), pp. 161-6, 1983, ISSN: 0032-7484.

Abstract | Links:

90 entries « 9 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
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