Dr. Dimcho Bachvarov received his B.Sc. and M.Sc. degrees from the University of Sofia in 1975-1978. He obtained his Ph.D. degree in 1986 from the Institute of Molecular Biology at the Bulgarian Academy of Science. In 1994, he was appointed as Adjunct Professor at Laval University’s department of Pharmacology. Consecutively, Dr. Bachvarov was promoted to Assistant Professor (1997), Associate Professor (2002), and since 2005 he has been a Full Professor at Laval University’s Department of Molecular Medicine. During his academic career, Dr. Bachvarov has received different Scholarship Awards, with the most representative being the Ernest J.B. Tomlinson Scholarship Award from the Kidney Foundation of Canada and other Scholarship Awards (Junior and Senior) from Fonds de recherche du Québec – Santé (FRQ-S).

His research interests are focused on studying the initiation and progression mechanisms of epithelial ovarian cancer (EOC) and improving treatment for this deadly disease, including the identification of early diagnostic or prognostic EOC markers. Dr. Bachvarov has published over 80 papers, predominantly in the EOC research field, and has received funding from CIHR, NSERC, CFI, FRQ-S, CRS and the Terry-Fox Research Institute (TFRI). He has been a co-founder and an active member of the provincial Réseau de Recherche en Cancer (RRCancer, established in 2000; see http://www.rrcancer.ca/), and since then, he has been a co-Chair of the Research Committee of the RRCancer axis entitled “Research and Solid State Tumour Biobank”. Following the establishment of RRCancer, Dr. Bachvarov was also in charge of the organization for the RRCancer-supported ovarian tumor bank in the Centre de recherche sur le cancer de l’Université Laval and the Hôtel-Dieu de Québec Hospital (the bank currently contains EOC specimens from about 3,000 patients). He is also the Head of the RRCancer Core Genomic Facility in Québec city. This facility is based on the Agilent dual channel detection microarray platform and has all the necessary equipment, complementary software and expertise required to perform different microarray experiments, including global gene expression and microRNA expression analyses, methylation DNA microarray-based analyses, array-CGH/CNV and Chip-on-CHIP analyses. The Core Genomic Facility in Québec city is providing a genomics and bioinformatics service to Canadian and foreign scientists who implement genomics approaches in their research (see: https://www.crc.ulaval.ca/la-recherche/plateformes/).

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4657
Québec, Québec
Canada G1R 2J6

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89 entries « 8 of 9 »

Marceau F, Hess JF, Bachvarov DR

The B1 receptors for kinins.

Journal Article

Pharmacol Rev, 50 (3), pp. 357-86, 1998, ISSN: 0031-6997.

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Bachvarov DR, Landry M, Pelletier I, Chevrette M, Betard C, Houde I, Bergeron J, Lebel M, Marceau F

Characterization of two polymorphic sites in the human kinin B1 receptor gene: altered frequency of an allele in patients with a history of end-stage renal failure.

Journal Article

J Am Soc Nephrol, 9 (4), pp. 598-604, 1998, ISSN: 1046-6673.

Abstract | Links:

Larrivée JF, Bachvarov DR, Houle F, Landry J, Huot J, Marceau F

Role of the mitogen-activated protein kinases in the expression of the kinin B1 receptors induced by tissue injury.

Journal Article

J Immunol, 160 (3), pp. 1419-26, 1998, ISSN: 0022-1767.

Abstract | Links:

Marceau F, Bachvarov DR

Kinin receptors.

Journal Article

Clin Rev Allergy Immunol, 16 (4), pp. 385-401, 1998, ISSN: 1080-0549.

Abstract | Links:

Marceau F, Larrivée JF, Saint-Jacques E, Bachvarov DR

The kinin B1 receptor: an inducible G protein coupled receptor.

Journal Article

Can J Physiol Pharmacol, 75 (6), pp. 725-30, 1997, ISSN: 0008-4212.

Abstract | Links:

Bachvarov DR, Hess JF, Menke JG, Larrivée JF, Marceau F

Structure and genomic organization of the human B1 receptor gene for kinins (BDKRB1).

Journal Article

Genomics, 33 (3), pp. 374-81, 1996, ISSN: 0888-7543.

Abstract | Links:

Bachvarov DR, Saint-Jacques E, Larrivée JF, Levesque L, Rioux F, Drapeau G, Marceau F

Cloning and pharmacological characterization of the rabbit bradykinin B2 receptor.

Journal Article

J Pharmacol Exp Ther, 275 (3), pp. 1623-30, 1995, ISSN: 0022-3565.

Abstract | Links:

Levesque L, Larrivée JF, Bachvarov DR, Rioux F, Drapeau G, Marceau F

Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta.

Journal Article

Br J Pharmacol, 116 (1), pp. 1673-9, 1995, ISSN: 0007-1188.

Abstract | Links:

Dimitrov SI, Bachvarov D, Moss T

Mapping of a sequence essential for the nuclear transport of the Xenopus ribosomal transcription factor xUBF using a simple coupled translation-transport and acid extraction approach.

Journal Article

DNA Cell Biol, 12 (3), pp. 275-81, 1993, ISSN: 1044-5498.

Abstract | Links:

Labrie F, Sugimoto Y, Luu-The V, Simard J, Lachance Y, Bachvarov D, Leblanc G, Durocher F, Paquet N

Structure of human type II 5 alpha-reductase gene.

Journal Article

Endocrinology, 131 (3), pp. 1571-3, 1992, ISSN: 0013-7227.

Abstract | Links:

89 entries « 8 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
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