Dr. Gagnon is an adult endocrinologist. She has completed a 3-year research fellowship in metabolic bone diseases and phosphocalcic metabolism disorders. She is a clinician researcher at the CHU de Québec-Laval University Research Centre and a Professor at Laval University’s School of Medicine. She is also an associate researcher at Laval University’s Institute of Nutrition and Functional Foods. Her research focusses on the impact of obesity and type 2 diabetes treatments on bone health (including bariatric surgery and medical treatments). She also works on the effects of vitamin D and other nutrients on the prevention of type 2 diabetes and, finally, on phosphocalcic metabolism disorders. Her research is financed by Diabète Québec, Diabetes Canada, and the Canadian Institutes of Health Research.

Dr. Gagnon has received several prizes and honours, including the 2017 research prize from the Fédération des médecins spécialistes du Québec, a 2015 young investigator award from the American Society for Bone and Mineral Research, an award at the 2015 International Symposium on the Nutritional Aspects of Osteoporosis, and a 2019 Jean-Davignon young investigator award from the FRQ-S cardiometabolic, diabetes and obesity network.

To evaluate the impact of bariatric surgery and other obesity treatments on bone health

Bariatric surgery is associated with clear benefits on reducing obesity-related diseases. However, data cumulated over the last few years suggest that certain types of bariatric procedures have adverse effects on bone health. Moreover, the effect of medical weight loss on bone health is not well studied. Dr. Gagnon’s research aims at evaluating the impact of different types of bariatric procedures and obesity treatments on bone markers, and to determine the mechanisms by which they influence bone health.

To evaluate the effects of vitamin D and other nutrients on the risk of developing type 2 diabetes

Certain nutrients hold promise to decrease the risk of diabetes in people at high risk. Dr. Gagnon’s expertise is to perform clinical trials to evaluate whether these nutrients are effective.

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Turcotte AF, Kukuljan S, Dalla Via J, Gagnon C, Abbott G, Daly RM

Changes in spinal bone density, back muscle size, and visceral adipose tissue and their interaction following a multi-component exercise program in older men: secondary analysis of an 18-month randomized controlled trial.

Journal Article

Osteoporos Int, 31 (10), pp. 2025-2035, 2020, ISSN: 0937-941X.

Abstract | Links:

Savard C, Plante AS, Carbonneau E, Gagnon C, Robitaille J, Lamarche B, Lemieux S, Morisset AS

Do pregnant women eat healthier than non-pregnant women of childbearing age?

Journal Article

Int J Food Sci Nutr, 71 (6), pp. 757-768, 2020, ISSN: 0963-7486.

Abstract | Links:

Turcotte AF, Grenier-Larouche T, Lacombe J, Carreau AM, Carpentier AC, Mac-Way F, Tchernof A, Richard D, Biertho L, Lebel S, Marceau S, Ferron M, Gagnon C

Association between changes in bioactive osteocalcin and glucose homeostasis after biliopancreatic diversion.

Journal Article

Endocrine, 69 (3), pp. 526-535, 2020, ISSN: 0969-711X.

Abstract | Links:

Khorraminezhad L, Leclercq M, O'Connor S, Julien P, Weisnagel SJ, Gagnon C, Droit A, Rudkowska I

Dairy product intake modifies gut microbiota composition among hyperinsulinemic individuals.

Journal Article

Eur J Nutr, 2020, ISSN: 1436-6207.

Abstract | Links:

Lacombe J, Al Rifai O, Loter L, Moran T, Turcotte AF, Grenier-Larouche T, Tchernof A, Biertho L, Carpentier AC, Prud'homme D, Rabasa-Lhoret R, Karsenty G, Gagnon C, Jiang W, Ferron M

Measurement of bioactive osteocalcin in humans using a novel immunoassay reveals association with glucose metabolism and β-cell function.

Journal Article

Am J Physiol Endocrinol Metab, 318 (3), pp. E381-E391, 2020, ISSN: 0193-1849.

Abstract | Links:

Del Degan S, Dube F, Gagnon C, Boulet G

Risk Factors for Recurrent Diabetic Ketoacidosis in Adults With Type 1 Diabetes.

Journal Article

Can J Diab, 43 (7), pp. 472-476.e1, 2019, ISSN: 1499-2671.

Abstract | Links:

Lemieux P, Weisnagel JS, Caron AZ, Julien AS, Morisset AS, Carreau AM, Poirier J, Tchernof A, Robitaille J, Bergeron J, Marette A, Vohl MC, Gagnon C

Effects of 6-month vitamin D supplementation on insulin sensitivity and secretion: a randomised, placebo-controlled trial.

Journal Article

Eur J Endocrinol, 181 (3), pp. 287-299, 2019, ISSN: 0804-4643.

Abstract | Links:

O'Connor S, Julien P, Weisnagel SJ, Gagnon C, Rudkowska I

Impact of a High Intake of Dairy Product on Insulin Sensitivity in Hyperinsulinemic Adults: A Crossover Randomized Controlled Trial.

Journal Article

Curr Dev Nutr, 3 (8), pp. nzz083, 2019, ISSN: 2475-2991.

Abstract | Links:

Guenard F, Jacques H, Gagnon C, Marette A, Vohl MC

Acute Effects of Single Doses of Bonito Fish Peptides and Vitamin D on Whole Blood Gene Expression Levels: A Randomized Controlled Trial.

Journal Article

Int J Mol Sci, 20 (8), 2019.

Abstract | Links:

O'Connor S, Turcotte AF, Gagnon C, Rudkowska I

Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal Article

Adv Nutr, 10 (2), pp. 262-279, 2019, ISSN: 2161-8313.

Abstract | Links:

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Active projects

  • BEhaviors, Therapies, TEchnologies and hypoglycemic Risk in Type 1 diabetes: The BETTER study, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2018-04-01 to 2022-03-31
  • Bone health after bariatric surgery in patient with type 2 diabetes, Subvention, Association canadienne du diabète, Compétition de recherche 2017, from 2017-07-01 to 2021-12-31
  • Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Subvention, Institut universitaire de cardiologie et de pneumologie de Québec, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Demonstration of the prebiotic-like effects of camu-camu consumption against obesity-related disorders in humans, Subvention, The W. Garfield Weston Foundation, from 2019-07-01 to 2021-06-30
  • Determinants of bone and muscle quality and function in obesity with and without diabetes - BODI 2, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2019-12-18 to 2021-03-31
  • Institut sur la nutrition et les aliments fonctionnels (INAF), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2024-03-31
  • Insulinorésistance et santé osseuse chez l’obèse : rôle des nutriments et des facteurs hormonaux, Subvention, Fonds de recherche du Québec - Santé, Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, from 2017-10-01 to 2021-09-30
  • Perinatal research unit for a sustainable health of mother and child, Partenariat, Fondation Canadienne pour l'innovation (La), Fonds d'innovation (FI), from 2018-03-01 to 2020-09-30
  • Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects, Subvention, Instituts de recherche en santé du Canada, Subventions de recherche programmatique sur l’alimentation et la santé, from 2013-06-01 to 2021-03-31

Recently finished projects

  • Facteurs de risque et impacts de la carence en vitamine D chez les victimes de traumatisme craniocérébral modéré et grave: une étude rétrospective multicentrique., Subvention, Fonds de recherche du Québec - Santé, Consortium pour le développement de la recherche en traumatologie, from 2018-04-01 to 2020-03-31
Data provided by the Université Laval research projects registery