Dr. Gagnon is an adult endocrinologist. She has completed a 3-year research fellowship in metabolic bone diseases and phosphocalcic metabolism disorders. She is a clinician researcher at the CHU de Québec-Laval University Research Centre and a Professor at Laval University’s School of Medicine. She is also an associate researcher at Laval University’s Institute of Nutrition and Functional Foods. Her research focusses on the impact of obesity and type 2 diabetes treatments on bone health (including bariatric surgery and medical treatments). She also works on the effects of vitamin D and other nutrients on the prevention of type 2 diabetes and, finally, on phosphocalcic metabolism disorders. Her research is financed by Diabète Québec, Diabetes Canada, and the Canadian Institutes of Health Research.

Dr. Gagnon has received several prizes and honours, including the 2017 research prize from the Fédération des médecins spécialistes du Québec, a 2015 young investigator award from the American Society for Bone and Mineral Research, and an award at the 2015 International Symposium on the Nutritional Aspects of Osteoporosis.

To evaluate the impact of bariatric surgery and other obesity treatments on bone health

Bariatric surgery is associated with clear benefits on reducing obesity-related diseases. However, data cumulated over the last few years suggest that certain types of bariatric procedures have adverse effects on bone health. Moreover, the effect of medical weight loss on bone health is not well studied. Dr. Gagnon’s research aims at evaluating the impact of different types of bariatric procedures and obesity treatments on bone markers, and to determine the mechanisms by which they influence bone health.

To evaluate the effects of vitamin D and other nutrients on the risk of developing type 2 diabetes

Certain nutrients hold promise to decrease the risk of diabetes in people at high risk. Dr. Gagnon’s expertise is to perform clinical trials to evaluate whether these nutrients are effective.

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Del Degan S, Dube F, Gagnon C, Boulet G

Risk Factors for Recurrent Diabetic Ketoacidosis in Adults With Type 1 Diabetes.

Journal Article

Can J Diab, 43 (7), pp. 472-476.e1, 2019, ISSN: 1499-2671.

Abstract | Links:

O'Connor S, Greffard K, Leclercq M, Julien P, Weisnagel SJ, Gagnon C, Droit A, Bilodeau JF, Rudkowska I

Increased Dairy Product Intake Alters Serum Metabolite Profiles in Subjects at Risk of Developing Type 2 Diabetes.

Journal Article

Mol Nutr Food Res, 63 (19), pp. e1900126, 2019, ISSN: 1613-4125.

Abstract | Links:

O'Connor S, Julien P, Weisnagel SJ, Gagnon C, Rudkowska I

Impact of a High Intake of Dairy Product on Insulin Sensitivity in Hyperinsulinemic Adults: A Crossover Randomized Controlled Trial.

Journal Article

Curr Dev Nutr, 3 (8), pp. nzz083, 2019, ISSN: 2475-2991.

Abstract | Links:

Lemieux P, Weisnagel JS, Caron AZ, Julien AS, Morisset AS, Carreau AM, Poirier J, Tchernof A, Robitaille J, Bergeron J, Marette A, Vohl MC, Gagnon C

Effects of 6-month vitamin D supplementation on insulin sensitivity and secretion: a randomized, placebo-controlled trial.

Journal Article

Eur J Endocrinol, 2019, ISSN: 0804-4643.

Abstract | Links:

Guenard F, Jacques H, Gagnon C, Marette A, Vohl MC

Acute Effects of Single Doses of Bonito Fish Peptides and Vitamin D on Whole Blood Gene Expression Levels: A Randomized Controlled Trial.

Journal Article

Int J Mol Sci, 20 (8), 2019.

Abstract | Links:

Turcotte AF, Grenier-Larouche T, Ung RV, Simonyan D, Carreau AM, Carpentier AC, Mac-Way F, Michou L, Tchernof A, Biertho L, Lebel S, Marceau S, Gagnon C

Effects of Biliopancreatic Diversion on Bone Turnover Markers and Association with Hormonal Factors in Patients with Severe Obesity.

Journal Article

Obes Surg, 29 (3), pp. 990-998, 2019, ISSN: 0960-8923.

Abstract | Links:

O'Connor S, Turcotte AF, Gagnon C, Rudkowska I

Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal Article

Adv Nutr, 10 (2), pp. 262-279, 2019, ISSN: 2161-8313.

Abstract | Links:

Savard C, Lemieux S, Carbonneau E, Provencher V, Gagnon C, Robitaille J, Morisset AS

Trimester-Specific Assessment of Diet Quality in a Sample of Canadian Pregnant Women.

Journal Article

Int J Environ Res Public Health, 16 (3), 2019, ISSN: 1661-7827.

Abstract | Links:

Savard C, Lemieux S, Weisnagel SJ, Fontaine-Bisson B, Gagnon C, Robitaille J, Morisset AS

Correction: Savard et al. Trimester-Specific Dietary Intakes in a Sample of French-Canadian Pregnant Women in Comparison with National Nutritional Guidelines. Nutrients 2018, 10, 768.

Journal Article

Nutrients, 11 (1), 2019, ISSN: 2072-6643.

Abstract | Links:

Turcotte AF, Gagnon C

Obésité, diabète de type 2 et chirurgie bariatrique : quels sont leurs effets sur la santé des os ?

Journal Article

Nutr sci évol, 17 (1), pp. 20-24, 2019, ISSN: 1708-0452.

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Active projects

  • Bone health after bariatric surgery in patient with type 2 diabetes, Subvention, Association canadienne du diabète, Compétition de recherche 2017, from 2017-07-01 to 2020-06-30
  • Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Subvention, Institut universitaire de cardiologie et de pneumologie de Québec, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Facteurs de risque et impacts de la carence en vitamine D chez les victimes de traumatisme craniocérébral modéré et grave: une étude rétrospective multicentrique., Subvention, Fonds de recherche du Québec - Santé, Consortium pour le développement de la recherche en traumatologie, from 2018-04-01 to 2020-03-31
  • Institut sur la nutrition et les aliments fonctionnels (INAF), Subvention, Fonds de recherche du Québec - Nature et technologies, Regroupements stratégiques NT, from 2017-04-01 to 2023-03-31
  • Insulinorésistance et santé osseuse chez l’obèse : rôle des nutriments et des facteurs hormonaux, Subvention, Fonds de recherche du Québec - Santé, Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, from 2017-10-01 to 2021-09-30
  • Perinatal research unit for a sustainable health of mother and child, Partenariat, Fondation Canadienne pour l'innovation (La), Fonds d'innovation (FI), from 2018-03-01 to 2020-03-31

Recently finished projects

  • Analyse de spécimens congelés pour recherche clinique, Subvention, Fondation du CHU de Québec, from 2018-04-17 to 2019-03-31
  • Centre de recherche en endocrinologie, métabolisme et inflammation, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-06-01 to 2018-04-30
  • Clinical outcomes and predictors of PITuitary disorders in patients with moderate and severe Traumatic Brain Injury: the PIT-TBI prospective multicenter pilot cohort study., Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-04-01 to 2019-03-31
  • Explorations clinique et moléculaire des fractures de stress d'origine génétique, incluant les fractures atypiques des fémurs, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-08-01 to 2019-03-31
  • Prix Jeune chercheur Jean-Davignon 2019 du Réseau CMDO, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-10-03 to 2019-03-31
  • Stage étudiant intercentre financé (concours 2018-2019), Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2018-11-30 to 2019-03-31
  • Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects, Subvention, Instituts de recherche en santé du Canada, Subventions de recherche programmatique sur l’alimentation et la santé, from 2013-06-01 to 2018-05-31
Data provided by the Université Laval research projects registery