Senior investigator at the CHU de Québec-Laval University Research Center, Dr. Côté is also full professor at the department of Réadaptation/Rehabiliatiton and has been a member of the School of medicine’s executive committee as associate dean for the rehabilitation programs since 2010.

For over 20 years, he has been conducting research work focussing on the pathophysiology of musculoskeletal trauma and injuries. More specifically, he is interested in elucidating the cellular and molecular mechanisms involved in the cascades behind the coordinated actions leading to the degeneration and regeneration of muscle tissue following acute trauma or injury, mainly using animal and cellular models.

His most recent work aims at understanding the importance of the inflammatory reaction for the healing and regenerative processes in skeletal muscle; one goal is to identify the specific roles assumed by the various cells implicated during an innate inflammatory reaction like the one triggered in injured skeletal muscle; specifically, one objective is to determine how mast cells can modulate such a process and the prostaglandins involved. Lastly, we also conduct work whose goal is to determine how pharmacological anti-inflammatory strategies can interfere with degenerative and regenerative processes.

CHUL
2705, boulevard Laurier
P-09641
Québec, Québec
Canada G1V 4G2

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Rousseau J, Dumont N, Lebel C, Quenneville SP, Cote CH, Frenette J, Tremblay JP

Dystrophin expression following the transplantation of normal muscle precursor cells protects mdx muscle from contraction-induced damage.

Journal Article

Cell Transplant, 19 (5), pp. 589-96, 2010, ISSN: 0963-6897.

Abstract | Links:

Houngbedji GM, Cote CH, Small PL, Frenette J

Limited repair and structural damages displayed by skeletal muscles loaded with mycolactone.

Journal Article

Microbes Infect, 11 (2), pp. 238-44, 2009, ISSN: 1286-4579.

Abstract | Links:

Pérez HM, Janssoone X, Côté C, Guderley H

Comparison between in vivo force recordings during escape responses and in vitro contractile capacities in the sea scallop Placopecten magellanicus

Journal Article

Journal of Shellfish Research, 28 (3), pp. 491-495, 2009, ISSN: 0730-8000.

Lefort N, St-Amand E, Morasse S, Cote CH, Marette A

The alpha-subunit of AMPK is essential for submaximal contraction-mediated glucose transport in skeletal muscle in vitro.

Journal Article

Am J Physiol Endocrinol Metab, 295 (6), pp. E1447-54, 2008, ISSN: 0193-1849.

Abstract | Links:

Cote CH, Tremblay MH, Duchesne E, Lapointe BM

Inflammation-induced leukocyte accumulation in injured skeletal muscle: role of mast cells.

Journal Article

Muscle Nerve, 37 (6), pp. 754-63, 2008, ISSN: 0148-639X.

Abstract | Links:

Debigare R, Maltais F, Cote CH, Michaud A, Caron MA, Mofarrahi M, Leblanc P, Hussain SN

Profiling of mRNA expression in quadriceps of patients with COPD and muscle wasting.

Journal Article

COPD, 5 (2), pp. 75-84, 2008, ISSN: 1541-2555.

Abstract | Links:

Dumont N, Lepage K, Cote CH, Frenette J

Mast cells can modulate leukocyte accumulation and skeletal muscle function following hindlimb unloading.

Journal Article

J Appl Physiol, 103 (1), pp. 97-104, 2007, ISSN: 8750-7587.

Abstract | Links:

Marsolais D, Côté CH, Frenette J

Pifithrin-alpha, an inhibitor of p53 transactivation, alters the inflammatory process and delays tendon healing following acute injury.

Journal Article

Am J Physiol Regul Integr Comp Physiol, 292 (1), pp. R321-7, 2007, ISSN: 0363-6119.

Abstract | Links:

Marsolais D, Duchesne E, Cote CH, Frenette J

Inflammatory cells do not decrease the ultimate tensile strength of intact tendons in vivo and in vitro: protective role of mechanical loading.

Journal Article

J Appl Physiol, 102 (1), pp. 11-7, 2007, ISSN: 8750-7587.

Abstract | Links:

Skuk D, Goulet M, Roy B, Piette V, Cote CH, Chapdelaine P, Hogrel JY, Paradis M, Bouchard JP, Sylvain M, Lachance JG, Tremblay JP

First test of a "high-density injection" protocol for myogenic cell transplantation throughout large volumes of muscles in a Duchenne muscular dystrophy patient: eighteen months follow-up.

Journal Article

Neuromuscul Disord, 17 (1), pp. 38-46, 2007, ISSN: 0960-8966.

Abstract | Links:

45 entries « 2 of 5 »
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  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
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