Senior investigator at the CHU de Québec-Laval University Research Center, Dr. Côté is also full professor at the department of Réadaptation/Rehabiliatiton and has been a member of the School of medicine’s executive committee as associate dean for the rehabilitation programs since 2010.

For over 20 years, he has been conducting research work focussing on the pathophysiology of musculoskeletal trauma and injuries. More specifically, he is interested in elucidating the cellular and molecular mechanisms involved in the cascades behind the coordinated actions leading to the degeneration and regeneration of muscle tissue following acute trauma or injury, mainly using animal and cellular models.

His most recent work aims at understanding the importance of the inflammatory reaction for the healing and regenerative processes in skeletal muscle; one goal is to identify the specific roles assumed by the various cells implicated during an innate inflammatory reaction like the one triggered in injured skeletal muscle; specifically, one objective is to determine how mast cells can modulate such a process and the prostaglandins involved. Lastly, we also conduct work whose goal is to determine how pharmacological anti-inflammatory strategies can interfere with degenerative and regenerative processes.

CHUL
2705, boulevard Laurier
RC-9500
Québec, Québec
Canada G1V 4G2

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Côté CH, Bouchard P, Duchesne E

Identification of New Targets Used by 15-deoxy-delta-12,14-Prostaglandin J2 to Stimulate Skeletal

Journal Article

Ann Sports Med Res, 2 (4), pp. 1027, 2015.

Cote CH, Bouchard P, van Rooijen N, Marsolais D, Duchesne E

Monocyte depletion increases local proliferation of macrophage subsets after skeletal muscle injury.

Journal Article

BMC Musculoskelet Disord, 14 , pp. 359, 2013.

Abstract | Links:

Duchesne E, Bouchard P, Roussel MP, Cote CH

Mast cells can regulate skeletal muscle cell proliferation by multiple mechanisms.

Journal Article

Muscle Nerve, 48 (3), pp. 403-14, 2013, ISSN: 0148-639X.

Abstract | Links:

Dort J, Leblanc N, Maltais-Giguere J, Liaset B, Cote CH, Jacques H

Beneficial effects of cod protein on inflammatory cell accumulation in rat skeletal muscle after injury are driven by its high levels of arginine, glycine, taurine and lysine.

Journal Article

PLoS ONE, 8 (10), pp. e77274, 2013.

Abstract | Links:

Lemire BB, Debigare R, Dube A, Theriault ME, Cote CH, Maltais F

MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease.

Journal Article

J Appl Physiol, 113 (1), pp. 159-66, 2012, ISSN: 8750-7587.

Abstract | Links:

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Active projects

  • Centre hospitalier universitaire de Québec - CHU de Québec-Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31

Recently finished projects

  • Skeletal muscle endurance and wasting in COPD, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2011-01-10 to 2016-09-30
Data provided by the Université Laval research projects registery