Caroline Diorio has a PhD in epidemiology (2005). Following her studies in bioinformatics and molecular oncology (2005-2008), she set up her research laboratory at Saint-Sacrement Hospital, which is part of the CHU de Québec-Laval University network, where she oversees the storage of breast cancer samples for the Tissue and Data Bank Axis of the Cancer Research Network. She holds a senior research grant and is also an associate professor and the director of epidemiology programs in Laval University’s Department of Social and Preventive Medicine. Dr Diorio is also part of the research group from the Centre des maladies du sein du CHU de Québec-Université Laval. She is the author or co-author of over 80 peer-reviewed publications in scientific journals, one third of these publications focusing on breast tissue density:  a well-established and intermediary risk factor for breast cancer.

Her most recent research projects aim at a more personalized approach to the prevention and treatment of breast cancer. On one hand, her work aims at understanding how our lifestyle can influence the onset, evolution and treatment of breast cancer, to develop personalized prevention and treatment strategies for this type of cancer. Among the different life habits studied, she is mainly interested in obesity, physical activity, and nutrition. On the other hand, the heart of her work focuses on the identification of molecular risk and prognosis markers for breast cancer that can be modulated through changes in our lifestyle habits or can be targeted by preventive and therapeutic agents. Among others, she studies inflammatory, hormonal, metabolic, genetic and epigenetic markers in the blood, and the various components of breast tissue, as well as breast lesions of varying degrees of severity. Her laboratory is funded by the Canadian Institutes of Health Research, theFondation du cancer du sein du Québec, and the Fonds de recherche du Québec-santé.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
J0-16
Québec, Québec
Canada G1S 4L8
81 entries « 7 of 9 »

Diorio C, Dumas I

Relations of omega-3 and omega-6 intake with mammographic breast density.

Journal Article

Cancer Causes Control, 25 (3), pp. 339-51, 2014, ISSN: 0957-5243.

Abstract | Links:

Hogue JC, Morais L, Provencher L, Desbiens C, Poirier B, Poirier E, Jacob S, Diorio C

Characteristics associated with upgrading to invasiveness after surgery of a DCIS diagnosed using percutaneous biopsy.

Journal Article

Anticancer Res, 34 (3), pp. 1183-91, 2014, ISSN: 0250-7005.

Abstract | Links:

Diorio C, Dumas I, Sandanger TM, Ayotte P

Levels of circulating polychlorinated biphenyls and mammographic breast density.

Journal Article

Anticancer Res, 33 (12), pp. 5483-9, 2013, ISSN: 0250-7005.

Abstract | Links:

Hanna M, Diorio C

Does mammographic density reflect the expression of breast cancer markers?

Journal Article

Climacteric, 16 (4), pp. 407-16, 2013, ISSN: 1369-7137.

Abstract | Links:

Lemieux J, Diorio C, Cote MA, Provencher L, Barabe F, Jacob S, St-Pierre C, Demers E, Tremblay-Lemay R, Nadeau-Larochelle C, Michaud A, Laflamme C

Alcohol and HER2 polymorphisms as risk factor for cardiotoxicity in breast cancer treated with trastuzumab.

Journal Article

Anticancer Res, 33 (6), pp. 2569-76, 2013, ISSN: 0250-7005.

Abstract | Links:

Furrer D, Jacob S, Caron C, Sanschagrin F, Provencher L, Diorio C

Validation of a new classifier for the automated analysis of the human epidermal growth factor receptor 2 (HER2) gene amplification in breast cancer specimens.

Journal Article

Diagn Pathol, 8 , pp. 17, 2013.

Abstract | Links:

Diorio C, Lemieux J, Provencher L, Hogue JC, Vachon E

Aromatase inhibitors in obese breast cancer patients are not associated with increased plasma estradiol levels.

Journal Article

Breast Cancer Res Treat, 136 (2), pp. 573-9, 2012, ISSN: 0167-6806.

Abstract | Links:

Provencher L, Diorio C, Hogue JC, Doyle C, Jacob S

Does breast cancer tumor size really matter that much?

Journal Article

Breast, 21 (5), pp. 682-5, 2012, ISSN: 0960-9776.

Abstract | Links:

Mouriaux F, Diorio C, Bergeron D, Berchi C, Rousseau A

Liver function testing is not helpful for early diagnosis of metastatic uveal melanoma.

Journal Article

Ophthalmology, 119 (8), pp. 1590-5, 2012, ISSN: 0161-6420.

Abstract | Links:

Provencher L, Jacob S, Cote G, Hogue JC, Desbiens C, Poirier B, Raiche I, Le Regent L, Diorio C

Low frequency of cancer occurrence in same breast quadrant diagnosed with lobular neoplasia at percutaneous needle biopsy.

Journal Article

Radiology, 263 (1), pp. 43-52, 2012, ISSN: 0033-8419.

Abstract | Links:

81 entries « 7 of 9 »
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Active projects

  • Centre de recherche du CHU de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2022-06-13
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2021-03-31
  • Design for Better Health: User-Centred Design and Evaluation of Interactive Media for Health Education, Communication and Decision-Making, Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2016-07-01 to 2021-06-30
  • Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2024-09-30
  • Omega-3 fatty acids in the prevention of breast cancer: role of obesity-related markers in breast tissues, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2018-10-01 to 2026-09-30

Recently finished projects

  • Banque de tissu Sein-Ovaire, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2000-01-01 to 2019-06-30
  • Exposition cumulée aux stresseurs psychosociaux, marqueurs inflammatoires, télomères et fonction cognitive : une étude prospective de 20 ans, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2019-06-30
  • Une approche personnalisée pour la prévention et le traitement du cancer du sein, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2017-08-01 to 2020-07-31
Data provided by the Université Laval research projects registery