Caroline Diorio has a PhD in epidemiology (2005). Following her studies in bioinformatics and molecular oncology (2005-2008), she set up her research laboratory at Saint-Sacrement Hospital, which is part of the CHU de Québec-Laval University network, where she oversees the storage of breast cancer samples for the Tissue and Data Bank Axis of the Cancer Research Network. She holds a senior research grant and is also an associate professor and the director of epidemiology programs in Laval University’s Department of Social and Preventive Medicine. Dr Diorio is also part of the research group from the Centre des maladies du sein du CHU de Québec-Université Laval. She is the author or co-author of over 80 peer-reviewed publications in scientific journals, one third of these publications focusing on breast tissue density:  a well-established and intermediary risk factor for breast cancer.

Her most recent research projects aim at a more personalized approach to the prevention and treatment of breast cancer. On one hand, her work aims at understanding how our lifestyle can influence the onset, evolution and treatment of breast cancer, to develop personalized prevention and treatment strategies for this type of cancer. Among the different life habits studied, she is mainly interested in obesity, physical activity, and nutrition. On the other hand, the heart of her work focuses on the identification of molecular risk and prognosis markers for breast cancer that can be modulated through changes in our lifestyle habits or can be targeted by preventive and therapeutic agents. Among others, she studies inflammatory, hormonal, metabolic, genetic and epigenetic markers in the blood, and the various components of breast tissue, as well as breast lesions of varying degrees of severity. Her laboratory is funded by the Canadian Institutes of Health Research, theFondation du cancer du sein du Québec, and the Fonds de recherche du Québec-santé.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
Québec, Québec
Canada G1S 4L8

Latest news

Data not available

58 entries « 1 of 12 »

Furrer D, Jacob S, Michaud A, Provencher L, Lemieux J, Diorio C

Association of Tobacco Use, Alcohol Consumption and HER2 Polymorphisms With Response to Trastuzumab in HER2-Positive Breast Cancer Patients.

Journal Article

Clin Breast Cancer, 18 (4), pp. e687-e694, 2018, ISSN: 1526-8209.

Abstract | Links:

Nabi H, Diorio C

Body mass index and clinical outcomes in trastuzumab-treated metastatic breast cancer patients: An alternative explanation for the lack of association.

Journal Article

Breast, 39 , pp. 150-151, 2018, ISSN: 0960-9776.

| Links:

Poirier E, Desbiens C, Poirier B, Boudreau D, Jacob S, Lemieux J, Doyle C, Diorio C, Hogue JC, Provencher L

In response to: Long-term overall survival of patients diagnosed with pure tubular carcinoma of the breast might be affected by increased co-morbidities.

Journal Article

J Surg Oncol, 117 (7), pp. 1615, 2018, ISSN: 0022-4790.

| Links:

Poirier E, Desbiens C, Poirier B, Boudreau D, Jacob S, Lemieux J, Doyle C, Diorio C, Hogue JC, Provencher L

Characteristics and long-term survival of patients diagnosed with pure tubular carcinoma of the breast.

Journal Article

J Surg Oncol, 117 (6), pp. 1137-1143, 2018, ISSN: 0022-4790.

Abstract | Links:

Nabi H, Guertin JR, Talbot D, Diorio C

Body-mass index and metastatic melanoma outcomes.

Journal Article

Lancet Oncol, 19 (5), pp. e226, 2018, ISSN: 1470-2045.

| Links:

58 entries « 1 of 12 »

Active projects

  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Centre hospitalier universitaire de Québec - CHU de Québec-Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2020-06-30
  • Design for Better Health: User-Centred Design and Evaluation of Interactive Media for Health Education, Communication and Decision-Making, Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2016-07-01 to 2021-06-30
  • Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2020-06-30
  • Exposition cumulée aux stresseurs psychosociaux, marqueurs inflammatoires, télomères et fonction cognitive : une étude prospective de 20 ans, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2019-06-30
  • Une approche personnalisée pour la prévention et le traitement du cancer du sein, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2017-08-01 to 2020-07-31

Recently finished projects

  • Axe banque de tissus et de données BTD, Subvention, Fondation du cancer du sein du Québec, from 2011-04-01 to 2016-06-30
  • Banque de tissu Sein-Ovaire, Subvention, Fonds de recherche du Québec - Santé, Réseaux thématiques de recherche, from 2000-01-01 to 2016-06-30
  • DNA methylation in normal breast tissue associated to risk of second contralateral breast cancer., Subvention, L'Institut de recherche de la Société canadienne du cancer, Subventions pour l'innovation, from 2014-02-01 to 2018-01-30
  • Impact of obesity and epigenetic markers on the efficacy of aromatase inhibitors treatments.(FONDS 0493), Subvention, Fondation de l'Université Laval, from 2014-11-05 to 2016-11-04
  • Impact of obesity and epigenetic markers on the efficacy of aromatase inhibitors treatments., Subvention, Fondation du CHU de Québec, from 2015-06-26 to 2016-06-25
  • Infrastructure for a breast cancer prevention personalized approach, Partenariat, Fondation Canadienne pour l'innovation (La), Fonds des leaders John-R.-Evans (FLJR), from 2016-09-01 to 2017-12-31
  • Omega-3 fatty acids and the obesity-related markers in breast tissues: A personalized approach to breast cancer prevention., Subvention, L'Institut de recherche de la Société canadienne du cancer, Bourse de développement de capacité en prévention, from 2014-08-01 to 2017-07-31
  • Quebec Breast Cancer foundation Tissue Microarray Consortium for biomarker, Subvention, Fondation du cancer du sein du Québec, from 2016-01-27 to 2017-03-31
  • Une approche personnalisée pour la prévention du cancer du sein., Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2014-07-01 to 2016-06-30
Data provided by the Université Laval research projects registery