Caroline Diorio has a PhD in epidemiology (2005). Following her studies in bioinformatics and molecular oncology (2005-2008), she set up her research laboratory at Saint-Sacrement Hospital, which is part of the CHU de Québec-Laval University network, where she oversees the storage of breast cancer samples for the Tissue and Data Bank Axis of the Cancer Research Network. She holds a senior research grant and is also an associate professor and the director of epidemiology programs in Laval University’s Department of Social and Preventive Medicine. Dr Diorio is also part of the research group from the Centre des maladies du sein du CHU de Québec-Université Laval. She is the author or co-author of over 80 peer-reviewed publications in scientific journals, one third of these publications focusing on breast tissue density:  a well-established and intermediary risk factor for breast cancer.

Her most recent research projects aim at a more personalized approach to the prevention and treatment of breast cancer. On one hand, her work aims at understanding how our lifestyle can influence the onset, evolution and treatment of breast cancer, to develop personalized prevention and treatment strategies for this type of cancer. Among the different life habits studied, she is mainly interested in obesity, physical activity, and nutrition. On the other hand, the heart of her work focuses on the identification of molecular risk and prognosis markers for breast cancer that can be modulated through changes in our lifestyle habits or can be targeted by preventive and therapeutic agents. Among others, she studies inflammatory, hormonal, metabolic, genetic and epigenetic markers in the blood, and the various components of breast tissue, as well as breast lesions of varying degrees of severity. Her laboratory is funded by the Canadian Institutes of Health Research, theFondation du cancer du sein du Québec, and the Fonds de recherche du Québec-santé.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
J0-16
Québec, Québec
Canada G1S 4L8
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Perron L, Chang SL, Daigle JM, Vandal N, Theberge I, Diorio C, Lemieux J, Pelletier E, Brisson J

Breast cancer subtype and screening sensitivity in the Quebec Mammography Screening Program.

Journal Article

J Med Screen, 26 (3), pp. 154-161, 2019, ISSN: 0969-1413.

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Ennour-Idrissi K, Ayotte P, Diorio C

Persistent Organic Pollutants and Breast Cancer: A Systematic Review and Critical Appraisal of the Literature.

Journal Article

Cancers (Basel), 11 (8), 2019, ISSN: 2072-6694.

Abstract | Links:

Moussa H, Nguile-Makao M, Robitaille K, Guertin MH, Allaire J, Pelletier JF, Moreel X, Gevariya N, Diorio C, Desmeules P, Tetu B, Lamarche B, Julien P, Fradet V

Omega-3 Fatty Acids Survey in Men under Active Surveillance for Prostate Cancer: from Intake to Prostate Tissue Level.

Journal Article

Nutrients, 11 (7), 2019, ISSN: 2072-6643.

Abstract | Links:

Brochu F, Plante PL, Drouin A, Gagnon D, Richard D, Durocher F, Diorio C, Marchand M, Corbeil J, Laviolette F

Mass spectra alignment using virtual lock-masses.

Journal Article

Sci Rep, 9 (1), pp. 8469, 2019, ISSN: 2045-2322.

Abstract | Links:

Kothari C, Ouellette G, Labrie Y, Jacob S, Diorio C, Durocher F

Identification of a gene signature for different stages of breast cancer development that could be used for early diagnosis and specific therapy.

Journal Article

Oncotarget, 9 (100), pp. 37407-37420, 2018, ISSN: 1949-2553.

Abstract | Links:

Nabi H, Provencher L, Diorio C

RE: Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424).

Journal Article

J Natl Cancer Inst, 110 (12), pp. 1422-1423, 2018, ISSN: 0027-8874.

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Poirier E, Desbiens C, Poirier B, Boudreau D, Jacob S, Lemieux J, Doyle C, Diorio C, Hogue JC, Provencher L

Characteristics and long-term survival of patients diagnosed with pure tubular carcinoma of the breast.

Journal Article

J Surg Oncol, 117 (6), pp. 1137-1143, 2018, ISSN: 0022-4790.

Abstract | Links:

Trudel X, Gilbert-Ouimet M, Milot A, Duchaine CS, Vezina M, Laurin D, Sultan-Taieb H, Brisson C, The PROspective Québec (PROQ) Study on Work, Health: Investigators, collaborators

Cohort Profile: The PROspective Québec (PROQ) Study on Work and Health.

Journal Article

Int J Epidemiol, 2018, ISSN: 0300-5771.

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Hanna M, Dumas I, Orain M, Jacob S, Tetu B, Diorio C

Association between physical activity and the expression of mediators of inflammation in normal breast tissue among premenopausal and postmenopausal women.

Journal Article

Cytokine, 102 , pp. 151-160, 2018, ISSN: 1043-4666.

Abstract | Links:

Furrer D, Jacob S, Michaud A, Provencher L, Lemieux J, Diorio C

Association of Tobacco Use, Alcohol Consumption and HER2 Polymorphisms With Response to Trastuzumab in HER2-Positive Breast Cancer Patients.

Journal Article

Clin Breast Cancer, 18 (4), pp. e687-e694, 2018, ISSN: 1526-8209.

Abstract | Links:

64 entries « 1 of 7 »
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Active projects

  • Centre de recherche sur le cancer, Subvention, Institutionnel - BDR, BDR - Centres de recherche reconnus, from 1996-05-01 to 2023-04-30
  • Centres hospitaliers universitaires de Québec - Université Laval, Subvention, Centre hospitalier universitaire de Québec - Université Laval, Centres de recherche affiliés, from 2017-01-01 to 2099-12-31
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2020-06-30
  • Design for Better Health: User-Centred Design and Evaluation of Interactive Media for Health Education, Communication and Decision-Making, Subvention, Instituts de recherche en santé du Canada, Subventions Fondation, from 2016-07-01 to 2021-06-30
  • Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer, Subvention, Instituts de recherche en santé du Canada, Volet Projet: Concours pilotes, from 2016-07-01 to 2020-06-30
  • Omega-3 fatty acids in the prevention of breast cancer: role of obesity-related markers in breast tissues, Subvention, Instituts de recherche en santé du Canada, Subvention Projet, from 2018-10-01 to 2022-09-30
  • Une approche personnalisée pour la prévention et le traitement du cancer du sein, Subvention, Fonds de recherche du Québec - Santé, Chercheur-boursier Juniors 1 et 2, Seniors, from 2017-08-01 to 2020-07-31

Recently finished projects

  • Axe banque de tissus et de données BTD, Subvention, Fondation du cancer du sein du Québec, from 2011-04-01 to 2019-03-31
  • Exposition cumulée aux stresseurs psychosociaux, marqueurs inflammatoires, télomères et fonction cognitive : une étude prospective de 20 ans, Subvention, Instituts de recherche en santé du Canada, Subvention de fonctionnement, from 2014-07-01 to 2019-06-30
  • Infrastructure for a breast cancer prevention personalized approach, Partenariat, Fondation Canadienne pour l'innovation (La), Fonds des leaders John-R.-Evans (FLJR), from 2016-09-01 to 2019-03-31
Data provided by the Université Laval research projects registery