Dr. Têtu is professor emeritus at the Faculty of Medicine of Laval University and a regular researcher in the Oncology axis of the CHU Research Centre of Quebec since 1986. Since the beginning of his career, in addition to his clinical practice and research activities, particularly as a FRSQ senior clinical researcher grant holder, he held various executive positions such as head of the Division of Pathology in the Department of Molecular Biology, Medical Biochemistry and Pathology, Director of the Clinician-Scientist Residency Program and Graduate Program in Clinical Epidemiology, Medical Director of RUIS Telepathology Project at Laval University, Chief of Pathology Services at CHUQ and CHA, Assistant Director of Clinical Research at CHUQ Research Centre, Chair of the Advisory Committee on Anatomical Pathology at the Quebec Cancer Board (Ministry of Health) and Chair of the membership committee of the Canadian Association of Pathologists.

His research themes are:

Clinical validation of new tumor markers

His studies aim to validate tumor markers identified as potentially interesting for predicting the evolution of cancers. These studies are applied to cohorts of patients using histopathological approaches, and therefore involve expertise in cellular and molecular biology, pathology and epidemiology. Several studies use samples from a tumor bank that he has been developing for over 20 years.

Studying the benefits and challenges of using telepathology

Telepathology is a technology that Dr. Têtu has helped to introduce in eastern Quebec, and allows the pathologist to establish remote diagnostics, mainly in oncology. Collaborations with experts in information technology assessment, applied in telemedicine, help identify the socio-political, organizational, clinical, professional, legal and technological benefits and challenges related to the introduction of telepathology.

Hôpital Saint-Sacrement
1050, chemin Sainte-Foy
Service d'anatomopathologie et de cytologie
Québec, Québec
Canada G1S 4L8
153 entries « 3 of 16 »

Chen H, Li C, Peng X, Zhou Z, Weinstein JN, Cancer Genome Atlas Research Network, Liang H

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.

Journal Article

Cell, 173 (2), pp. 386-399.e12, 2018, ISSN: 0092-8674.

Abstract | Links:

Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortes-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, MC3 Working Group, Cancer Genome Atlas Research Network, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L

Comprehensive Characterization of Cancer Driver Genes and Mutations.

Journal Article

Cell, 173 (2), pp. 371-385.e18, 2018, ISSN: 0092-8674.

Abstract | Links:

Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Cancer Genome Atlas Research Network, Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L

Pathogenic Germline Variants in 10,389 Adult Cancers.

Journal Article

Cell, 173 (2), pp. 355-370.e14, 2018, ISSN: 0092-8674.

Abstract | Links:

Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kaminska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwinska P, Mazurek S, Mishra L, Heyn H, Krasnitz A, Godwin AK, Lazar AJ, Cancer Genome Atlas Research Network, Stuart JM, Hoadley KA, Laird PW, Noushmehr H, Wiznerowicz M

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.

Journal Article

Cell, 173 (2), pp. 338-354.e15, 2018, ISSN: 0092-8674.

Abstract | Links:

Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ, Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Cancer Genome Atlas Research Network, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N

Oncogenic Signaling Pathways in The Cancer Genome Atlas.

Journal Article

Cell, 173 (2), pp. 321-337.e10, 2018, ISSN: 0092-8674.

Abstract | Links:

Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortes-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, Olsen C, Kim J, Taylor AM, Cherniack AD, Akbani R, Suphavilai C, Nagarajan N, Stuart JM, Mills GB, Wyczalkowski MA, Vincent BG, Hutter CM, Zenklusen JC, Hoadley KA, Wendl MC, Shmulevich L, Lazar AJ, Wheeler DA, Getz G, Cancer Genome Atlas Research Network

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.

Journal Article

Cell, 173 (2), pp. 305-320.e10, 2018, ISSN: 0092-8674.

Abstract | Links:

Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM, Cancer Genome Atlas Network, Stuart JM, Benz CC, Laird PW

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Journal Article

Cell, 173 (2), pp. 291-304.e6, 2018, ISSN: 0092-8674.

Abstract | Links:

Way GP, Sanchez-Vega F, La K, Armenia J, Chatila WK, Luna A, Sander C, Cherniack AD, Mina M, Ciriello G, Schultz N, Cancer Genome Atlas Research Network, Sanchez Y, Greene CS

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Journal Article

Cell Rep, 23 (1), pp. 172-180.e3, 2018.

Abstract | Links:

Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J, Cancer Genome Atlas Research Network, Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.

Journal Article

Cell Rep, 23 (1), pp. 181-193.e7, 2018.

Abstract | Links:

Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W, Sumazin P, Chiu HS, Chen TW, Gunaratne P, Donehower L, Rader JS, Zuna R, Al-Ahmadie H, Lazar AJ, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK, Cancer Genome Atlas Research Network, Stuart JM, Laird PW, Hoadley KA, Weinstein JN, Peto M, Pickering CR, Chen Z, Van Waes C

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.

Journal Article

Cell Rep, 23 (1), pp. 194-212.e6, 2018.

Abstract | Links:

153 entries « 3 of 16 »
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