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Dimcho Bachvarov


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Principal area
Hôtel-Dieu de Québec
6, rue McMahon, 4657
Québec (Québec)

+1 418-525-4444, poste 15590
+1 418-691-2954

My research interests are focused on two major directions:

  1. Identification and characterization of cellular factors with prognostic importance for ovarian tumorigenesis and response to treatment (mechanisms of ovarian cancer chemoresistance);
  2. Studies on the, function and genetics of kinin receptors and their implications in cardiovascular and renal diseases and cancer.

Research project(s) recognized by Université Laval (in French)

Other active research project(s)

No active project

Recent publications (see all publication from this researcher)

Faddaoui A, Sheta R, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Ghani K, Bachvarov D. Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells. Cell cycle (Georgetown, Tex.) ,  2017. Epub
Papadopoulos T, Casemayou A, Neau E, Breuil B, Caubet C, Calise D, Thornhill BA, Bachvarova M, Belliere J, Chevalier RL, Moulos P, Bachvarov D, Buffin-Meyer B, Decramer S, Auriol FC, Bascands JL, Schanstra JP, Klein J. Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction. BMC systems biology,  2017. Epub
Bondi ML, Emma MR, Botto C, Augello G, Azzolina A, DI Gaudio F, Craparo EF, Cavallaro G, Bachvarov D, Cervello M. Biocompatible Lipid Nanoparticles as Carriers to Improve Curcumin Efficacy in Ovarian Cancer Treatment. Journal of agricultural and food chemistry,  2017. Epub
Faddaoui A, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Macdonald E, Vanderhyden B, Bachvarov D. The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells. Oncotarget,  2016. 7: 14125-42
Emma MR, Iovanna JL, Bachvarov D, Puleio R, Loria GR, Augello G, Candido S, Libra M, Gulino A, Cancila V, McCubrey JA, Montalto G, Cervello M. NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance. Cell death & disease,  2016. Epub
Sheta R, Woo CM, Roux-Dalvai F, Fournier F, Bourassa S, Droit A, Bertozzi CR, Bachvarov D. A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells. Journal of proteomics,  2016. 145: 91-102
Sheta R, Roux-Dalvai F, Woo CM, Fournier F, Bourassa S, Bertozzi CR, Droit A, Bachvarov D. Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells. Data in brief,  2016. 8: 342-9
Wang ZQ, Faddaoui A, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Guillemette C, Gobeil S, Macdonald E, Vanderhyden B, Bachvarov D. BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism. Oncotarget,  2015. 6: 31522-43
Ali AY, Kim JY, Pelletier JF, Vanderhyden BC, Bachvarov DR, Tsang BK. Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability. Molecular carcinogenesis,  2015. 54: 1301-14
Chen S, Yao X, Li Y, Saifudeen Z, Bachvarov D, El-Dahr SS. Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium. Development (Cambridge, England) ,  2015. 142: 1180-92
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