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Jacques-P. Tremblay

PhD Neurosciences UCSD

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Principal area
Centre Hospitalier de l'Université Laval (CHUL)
2705, boulevard Laurier, P-0-9300
Québec (Québec)

+1 418-525-4444, poste 42186
+1 418-654-2207

Research project(s) recognized by Université Laval (in French)

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Recent publications (see all publication from this researcher)

Duchene B, Iyombe-Engembe JP, Rousseau J, Tremblay JP, Ouellet DL. From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method. Methods in molecular biology (Clifton, N.J.) ,  2018. 1687: 267-283
Skuk D, Tremblay JP. Cell Therapy in Myology: Dynamics of Muscle Precursor Cell Death after Intramuscular Administration in Non-human Primates. Molecular therapy. Methods & clinical development,  2017. 5: 232-240
Perrin A, Rousseau J, Tremblay JP. Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160. Molecular therapy. Nucleic acids,  2017. 6: 68-79
Iyombe-Engembe JP, Tremblay JP. The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy Journal of Genetic Medicine and Gene Therapy,  2017. 1: 19-36
Ouellet DL, Duchêne B, Iyombe-Engembe JP, Tremblay JP. Advances & challenges of using CRISPR-Cas9 gene editing for treating Duchenne muscular dystrophy Cell & gene therapy insights,  2017. 3: 53-58
Ouellet DL, Cherif K, Rousseau J, Tremblay JP. Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich ataxia. Gene therapy,  2017. 24: 265-274
Skuk D, Tremblay JP. CD56+ Muscle Derived Cells but Not Retinal NG2+ Perivascular Cells of Nonhuman Primates are Myogenic after Intramuscular Transplantation in Immunodeficient Mice Journal of stem cell research & therapy [electronic resource],  2017. 7: 
Sanchez N, Chapdelaine P, Rousseau J, Raymond F, Corbeil J, Tremblay JP. Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique. Mitochondrion,  2016. 30: 59-66
Tremblay JP, Iyombe-Engembe JP, Duchene B, Ouellet DL. Gene Editing for Duchenne Muscular Dystrophy Using the CRISPR/Cas9 Technology: The Importance of Fine-tuning the Approach. Molecular therapy : the journal of the American Society of Gene Therapy,  2016. 24: 1888-1889
Iyombe-Engembe JP, Ouellet DL, Barbeau X, Rousseau J, Chapdelaine P, Lague P, Tremblay JP. Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method. Molecular therapy. Nucleic acids,  2016. 5: e283
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