CHU de Québec Tissue Engineering Platform offers a customized and experienced service of cell culture, production of reconstructed tissues and analysis of derived samples.
About the platform
- More than thirty years of experience in tissue engineering.
- Modern facilities of 4700 m2.
- One of the most recognized center in tissue and organ reconstruction in Canada.
- Clean rooms (class B, ISO 7) equipped for cell culture and used for clinical studies.
The advantages ot tissue engineering
Many in vitro models are available on the market, but those offered by our platform have the advantages of being produced in a controlled environment, to be of human origin, to be entirely biological (no exogenous materials) and to respond to their environment. Because of these features, our models present the advantage of being much more alike in vivo reality. Those models can be employed at different stages of research (fundamental or preclinical) in order to study different parameters such as toxicity, efficacy or mechanism of action of a treatment.
Some of our achievements
Effects of radiofrequency or light treatment on skin:
Kim, D. H., Lavoie, A., Ratté, G., Beaumont, C., Germain, L., & Larouche, D. (2015). Effect of 27-MHz radiofrequency on hair follicles: histological evaluation of skin treated ex vivo. Dermatologic Surgery, 41(4), 466-472.
Studies on wound healing mechanisms:
Couture, C., Zaniolo, K., Carrier, P., Lake, J., Patenaude, J., Germain, L., & Guérin, S. L. (2016). The tissue-engineered human cornea as a model to study expression of matrix metalloproteinases during corneal wound healing. Biomaterials, 78, 86-101.
Effects of molecules on cancer cells:
Gibot, L., Chabaud, S., Bouhout, S., Bolduc, S., Auger, F. A., & Moulin, V. J. (2015). Anticancer properties of chitosan on human melanoma are cell line dependent. International journal of biological macromolecules, 72, 370-379.
Our facilities are located on the site of the Hôpital de l’Enfant-Jésus in Québec City (Canada).
See our location.
For more information or to submit a project, please contact us.